recent publications

• academic article

  • McCoy, L. E., Falkowska, E., Doores, K. J., Le, K., Sok, D., van Gils, M. J., Euler, Z., Burger, J. A., Seaman, M. S., Sanders, R. W., Schuitemaker, H., Poignard, P., et al. Incomplete neutralization and deviation from sigmoidal neutralization curves for HIV broadly neutralizing monoclonal antibodies PLoS Pathogens  2015 11:e1005110  DOI:10.1371/journal.ppat.1005110  PMID:26267277  PMCID:PMC4534392
  • Falkowska, E., Le, K. M., Ramos, A., Doores, K. J., Lee, J. H., Blattner, C., Ramirez, A., Derking, R., van Gils, M. J., Liang, C. H., McBride, R., von Bredow, B., et al. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers Immunity  2014 40:657-668  DOI:10.1016/j.immuni.2014.04.009  PMID:24768347  PMCID:PMC4070425
  • Blattner, C., Lee, J. H., Sliepen, K., Derking, R., Falkowska, E., de la Pena, A. T., Cupo, A., Julien, J. P., van Gils, M., Lee, P. S., Peng, W., Paulson, J. C., et al. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers Immunity  2014 40:669-680  DOI:10.1016/j.immuni.2014.04.008  PMID:24768348  PMCID:PMC4057017
  • Ferguson, A. L., Falkowska, E., Walker, L. M., Seaman, M. S., Burton, D. R., Chakraborty, A. K. Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data PLoS One  2013 8:e80562  DOI:10.1371/journal.pone.0080562  PMID:24312481  PMCID:PMC3846483
  • Ota, T., Doyle-Cooper, C., Cooper, A. B., Huber, M., Falkowska, E., Doores, K. J., Hangartner, L., Le, K., Sok, D., Jardine, J., Lifson, J., Wu, X. L., et al. Anti-HIV B Cell lines as candidate vaccine biosensors Journal of Immunology  2012 189:4816-4824  DOI:10.4049/jimmunol.1202165  PMID:23066156  PMCID:PMC3626558
  • Falkowska, E., Ramos, A., Feng, Y., Zhou, T. Q., Moquin, S., Walker, L. M., Wu, X., Seaman, M. S., Wrin, T., Kwong, P. D., Wyatt, R. T., Mascola, J. R., et al. PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4 Journal of Virology  2012 86:4394-4403  DOI:10.1128/jvi.06973-11  PMID:22345481  PMCID:PMC3318667
  • Walker, L. M., Huber, M., Doores, K. J., Falkowska, E., Pejchal, R., Julien, J. P., Wang, S. K., Ramos, A., Chan-Hui, P. Y., Moyle, M., Mitcham, J. L., Hammond, P. W., et al. Broad neutralization coverage of HIV by multiple highly potent antibodies Nature  2011 477:466-470  DOI:10.1038/nature10373  PMID:21849977  PMCID:PMC3393110