recent publications

• academic article

  • Yang, W. Y., Wilson, H. D., Velagapudi, S. P., Disney, M. D. Inhibition of non-ATG translational events in cells via covalent small molecules targeting RNA Journal of the American Chemical Society  2015 137:5336-5345  DOI:10.1021/ja507448y  PMID:25825793  PMCID:PMC4856029
  • Velagapudi, S. P., Vummidi, B. R., Disney, M. D. Small molecule chemical probes of microRNA function Current Opinion in Chemical Biology  2015 24:97-103  DOI:10.1016/j.cbpa.2014.10.024  PMID:25500006  PMCID:PMC4382669
  • Velagapudi, S. P., Gallo, S. M., Disney, M. D. Sequence-based design of bioactive small molecules that target precursor microRNAs Nature Chemical Biology  2014 10:291-297  DOI:10.1038/nchembio.1452  PMID:24509821  PMCID:PMC3962094
  • Velagapudi, S. P., Disney, M. D. Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor Chemical Communications  2014 50:3027-3029  DOI:10.1039/c3cc00173c  PMID:24503738  PMCID:PMC4040211
  • Velagapudi, S. P., Disney, M. D. Defining RNA motif-aminoglycoside interactions via two-dimensional combinatorial screening and structure-activity relationships through sequencing Bioorganic & Medicinal Chemistry  2013 21:6132-6138  DOI:10.1016/j.bmc.2013.04.072  PMID:23719281  PMCID:PMC3789863
  • Velagapudi, S. P., Pushechnikov, A., Labuda, L. P., French, J. M., Disney, M. D. Probing a 2-aminobenzimidazole library for binding to RNA internal loops via two-dimensional combinatorial screening ACS Chemical Biology  2012 7:1902-1909  DOI:10.1021/cb300213g  PMID:22958065  PMCID:PMC3500435
  • Velagapudi, S. P., Seedhouse, S. J., French, J., Disney, M. D. Defining the rna internal loops preferred by benzimidazole derivatives via 2D combinatorial screening and computational analysis Journal of the American Chemical Society  2011 133:10111-10118  DOI:10.1021/ja200212b  PMID:21604752  PMCID:PMC3126894
  • Velagapudi, S. P., Seedhouse, S. J., Disney, M. D. Structure-activity relationships through sequencing (stARTS) defines optimal and suboptimal RNA motif targets for small molecules Angewandte Chemie-International Edition  2010 49:3816-3818  DOI:10.1002/anie.200907257  PMID:20397174  PMCID:PMC3021749
  • Disney, M. D., Labuda, L. P., Paul, D. J., Poplawski, S. G., Pushechnikov, A., Tran, T., Velagapudi, S. P., Wu, M., Childs-Disney, J. L. Two-dimensional combinatorial screening identifies specific aminoglycoside - RNA internal loop partners Journal of the American Chemical Society  2008 130:11185-11194  DOI:10.1021/ja803234t  PMID:18652457