recent publications
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academic article
- Zhou, T., Lynch, R. M., Chen, L., Acharya, P., Wu, X., Doria-Rose, N. A., Joyce, M. G., Lingwood, D., Soto, C., Bailer, R. T., Ernandes, M. J., Kong, R., et al. Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors Cell 2015 161:1280-1292 DOI:10.1016/j.cell.2015.05.007 PMID:26004070 PMCID:PMC4683157
- Asmal, M., Luedemann, C., Lavine, C. L., Mach, L. V., Balachandran, H., Brinkley, C., Denny, T. N., Lewis, M. G., Anderson, H., Pal, R., Sok, D., Le, K., et al. Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes Virology 2015 475:37-45 DOI:10.1016/j.virol.2014.10.032 PMID:25462344 PMCID:PMC4280322
- Huang, J., Kang, B. H., Pancera, M., Lee, J. H., Tong, T., Feng, Y., Imamichi, H., Georgiev, I. S., Chuang, G. Y., Druz, A., Doria-Rose, N. A., Laub, L., et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface Nature 2014 515:138-142 DOI:10.1038/nature13601 PMID:25186731 PMCID:PMC4224615
- Zhou, T., Zhu, J., Wu, X., Moquin, S., Zhang, B., Acharya, P., Georgiev, I. S., Altae-Tran, H. R., Chuang, G. Y., Joyce, M. G., Kwon, Y. D., Longo, N. S., et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies Immunity 2013 39:245-258 DOI:10.1016/j.immuni.2013.04.012 PMID:23911655 PMCID:PMC3985390
- Pancera, M., Shahzad-ul-Hussan, S., Doria-Rose, N. A., McLellan, J. S., Bailer, R. T., Dai, K., Loesgen, S., Louder, M. K., Staupe, R. P., Yang, Y., Zhang, B., Parks, R., et al. Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16 Nature Structural & Molecular Biology 2013 20:804-813 DOI:10.1038/nsmb.2600 PMID:23708607 PMCID:PMC4046252
- Liao, H. X., Lynch, R., Zhou, T., Gao, F., Alam, S. M., Boyd, S. D., Fire, A. Z., Roskin, K. M., Schramm, C. A., Zhang, Z., Zhu, J., Shapiro, L., et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Nature 2013 496:469-476 DOI:10.1038/nature12053 PMID:23552890 PMCID:PMC3637846
- Zhu, J., Ofek, G., Yang, Y. P., Zhang, B. S., Louder, M. K., Lu, G., McKee, K., Pancera, M., Skinner, J., Zhang, Z. H., Parks, R., Eudailey, J., et al. Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains Proceedings of the National Academy of Sciences of the United States of America 2013 110:6470-6475 DOI:10.1073/pnas.1219320110 PMID:23536288 PMCID:PMC3631616
- Huang, J. H., Ofek, G., Laub, L., Louder, M. K., Doria-Rose, N. A., Longo, N. S., Imamichi, H., Bailer, R. T., Chakrabarti, B., Sharma, S. K., Alam, S. M., Wang, T., et al. Broad and potent neutralization of hiv-1 by a gp41-specific human antibody Nature 2012 491:406-12 DOI:10.1038/nature11544 PMID:23151583 PMCID:PMC4854285
- Doria-Rose, N. A., Georgiev, I., O'Dell, S., Chuang, G. Y., Staupe, R. P., McLellan, J. S., Gorman, J., Pancera, M., Bonsignori, M., Haynes, B. F., Burton, D. R., Koff, W. C., et al. A short segment of the hiv-1 gp120 v1/v2 region is a major determinant of resistance to v1/v2 neutralizing antibodies Journal of Virology 2012 86:8319-8323 DOI:10.1128/jvi.00696-12 PMID:22623764 PMCID:PMC3421697
- McLellan, J. S., Pancera, M., Carrico, C., Gorman, J., Julien, J. P., Khayat, R., Louder, R., Pejchal, R., Sastry, M., Dai, K. F., O'Dell, S., Patel, N., et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 Nature 2011 480:336-343 DOI:10.1038/nature10696 PMID:22113616 PMCID:PMC3406929
- Bonsignori, M., Hwang, K. K., Chen, X., Tsao, C. Y., Morris, L., Gray, E., Marshall, D. J., Crump, J. A., Kapiga, S. H., Sam, N. E., Sinangil, F., Pancera, M., et al. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors Journal of Virology 2011 85:9998-10009 DOI:10.1128/jvi.05045-11 PMID:21795340 PMCID:PMC3196428
- Jiang, C. L., Parrish, N. F., Wilen, C. B., Li, H., Chen, Y., Pavlicek, J. W., Berg, A., Lu, X. Z., Song, H. S., Tilton, J. C., Pfaff, J. M., Henning, E. A., et al. Primary infection by a human immunodeficiency virus with atypical coreceptor tropism Journal of Virology 2011 85:10669-10681 DOI:10.1128/jvi.05249-11 PMID:21835785 PMCID:PMC3187499
- Wu, X. L., Zhou, T. Q., Zhu, J., Zhang, B. S., Georgiev, I., Wang, C., Chen, X. J., Longo, N. S., Louder, M., McKee, K., O'Dell, S., Perfetto, S., et al. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing Science 2011 333:1593-1602 DOI:10.1126/science.1207532 PMID:21835983 PMCID:PMC3516815
- Li, Y. X., O'Dell, S., Walker, L. M., Wu, X. L., Guenaga, J., Feng, Y., Schmidt, S. D., McKee, K., Louder, M. K., Ledgerwood, J. E., Graham, B. S., Haynes, B. F., et al. Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01 Journal of Virology 2011 85:8954-8967 DOI:10.1128/jvi.00754-11 PMID:21715490 PMCID:PMC3165784
- Gnanakaran, S., Bhattacharya, T., Daniels, M., Keele, B. F., Hraber, P. T., Lapedes, A. S., Shen, T. Y., Gaschen, B., Krishnamoorthy, M., Li, H., Decker, J. M., Salazar-Gonzalez, J. F., et al. Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections PLoS Pathogens 2011 7:e1002209 DOI:10.1371/journal.ppat.1002209 PMID:21980282 PMCID:PMC3182927