recent publications

• academic article

  • Perry, J. J. P., Hearn, A. S., Cabelli, D. E., Nick, H. S., Tainer, J. A., Silverman, D. N. Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis Biochemistry  2009 48:3417-3424  DOI:10.1021/bi8023288  PMID:19265433  PMCID:PMC2756076
  • Greenleaf, W. B., Jefferson, J., Perry, P., Hearn, A. S., Cabelli, D. E., Lepock, J. R., Stroupe, M. E., Tainer, J. A., Nick, H. S., Silverman, D. N. Role of hydrogen bonding in the active site of human manganese superoxide dismutase Biochemistry  2004 43:7038-7045  DOI:10.1021/bi049888k  PMID:15170341
  • Hearn, A. S., Fan, L., Lepock, J. R., Luba, J. P., Greenleaf, W. B., Cabelli, D. E., Tainer, J. A., Nick, H. S., Silverman, D. N. Amino acid substitution at the dimeric interface of human manganese superoxide dismutase Journal of Biological Chemistry  2004 279:5861-5866  DOI:10.1074/jbc.M311310200  PMID:14638684
  • Hearn, A. S., Stroupe, M. E., Cabelli, D. E., Ramilo, C. A., Luba, J. P., Tainer, J. A., Nick, H. S., Silverman, D. N. Catalytic and structural effects of amino acid substitution at histidine 30 in human manganese superoxide dismutase: Insertion of valine Cγ into the substrate access channel Biochemistry  2003 42:2781-2789  DOI:10.1021/bi0266481  PMID:12627943
  • Hearn, A. S., Stroupe, M. E., Cabelli, D. E., Lepock, J. R., Tainer, J. A., Nick, H. S., Silverman, D. N. Kinetic analysis of product inhibition in human manganese superoxide dismutase Biochemistry  2001 40:12051-12058  DOI:10.1021/bi011047f  PMID:11580280
  • Cabelli, D. E., Guan, Y., Leveque, V., Hearn, A. S., Tainer, J. A., Nick, H. S., Silverman, D. N. Role of tryptophan 161 in catalysis by human manganese superoxide dismutase Biochemistry  1999 38:11686-11692  DOI:10.1021/bi9909142  PMID:10512624