recent publications

• academic article

  • Cai, G., Chaban, Y. L., Imasaki, T., Kovacs, J. A., Calero, G., Penczek, P. A., Takagi, Y., Asturias, F. J. Interaction of the mediator head module with RNA polymerase II Structure  2012 20:899-910  DOI:10.1016/j.str.2012.02.023  PMID:22579255  PMCID:PMC3383055
  • Imasaki, T., Calero, G., Cai, G., Tsai, K. L., Yamada, K., Cardelli, F., Erdjument-Bromage, H., Tempst, P., Berger, I., Kornberg, G. L., Asturias, F. J., Kornberg, R. D., et al. Architecture of the mediator head module Nature  2011 475:240-243  DOI:10.1038/nature10162  PMID:21725323  PMCID:PMC4109712
  • Cai, G., Imasaki, T., Yamada, K., Cardelli, F., Takagi, Y., Asturias, F. J. Mediator head module structure and functional interactions Nature Structural & Molecular Biology  2010 17:273-279  DOI:10.1038/nsmb.1757  PMID:20154708  PMCID:PMC2925518
  • Cai, G., Imasaki, T., Takagi, Y., Asturias, F. J. Mediator structural conservation and implications for the regulation mechanism Structure  2009 17:559-567  DOI:10.1016/j.str.2009.01.016  PMID:19368889  PMCID:PMC2673807
  • Takagi, Y., Calero, G., Brown, J. A., Ehrensberger, A. H., Hudmon, A., Asturias, F., Kornberg, R. D. Head module control of mediator interactions Molecular Cell  2006 23:355-364  DOI:10.1016/j.molcel.2006.06.007  PMID:16885025
  • Takagi, Y., Chadick, J. Z., Davis, J. A., Asturias, F. J. Preponderance of free mediator in the yeast Saccharomyces cerevisiae Journal of Biological Chemistry  2005 280:31200-31207  DOI:10.1074/jbc.C500150200  PMID:16002404
  • Takagi, Y., Masuda, C. A., Chang, W. H., Komori, H., Wang, D., Hunter, T., Joazeiro, C. A. P., Kornberg, R. D. Ubiquitin ligase activity of tfiih and the transcriptional response to DNA damage Molecular Cell  2005 18:237-243  DOI:10.1016/j.molcel.2005.03.007  PMID:15837426
  • Davis, J. A., Takagi, Y., Kornberg, R. D., Asturias, F. J. Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction Molecular Cell  2002 10:409-415  DOI:10.1016/s1097-2765(02)00598-1  PMID:12191485
  • Takagi, Y., Dyer, C. A., Curtiss, L. K. Platelet-enhanced apolipoprotein e production by human macrophages - a possible role in atherosclerosis Journal of Lipid Research  1988 29:859-867  PMID:3411246
  • Curtiss, L. K., Black, A. S., Takagi, Y., Plow, E. F. New mechanism for foam cell generation in atherosclerotic lesions Journal of Clinical Investigation  1987 80:367-373  DOI:10.1172/jci113081  PMID:2956278