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Grant, W.

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    • Rosenberg, L. H., Lafitte, M., Grant, W., Chen, W., Cleveland, J. L., Duckett, D. R. Development of an HTS-compatible assay for the discovery of Ulk1 inhibitors Journal of Biomolecular Screening  2015 20:913-920  DOI:10.1177/1087057115579391  PMID:25851035  PMCID:PMC4744088
    • Yin, Y., Lin, L., Ruiz, C., Khan, S., Cameron, M. D., Grant, W., Pocas, J., Eid, N., Park, H., Schroter, T., Lograsso, P. V., Feng, Y. Synthesis and biological evaluation of urea derivatives as highly potent and selective rho kinase inhibitors Journal of Medicinal Chemistry  2013 56:3568-3581  DOI:10.1021/jm400062r  PMID:23570561
    • Chowdhury, S., Chen, Y. T., Fang, X. G., Grant, W., Pocas, J., Cameron, M. D., Ruiz, C., Lin, L., Park, H., Schroter, T., Bannister, T. D., LoGrasso, P. V., et al. Amino acid derived quinazolines as Rock/PKA inhibitors Bioorganic & Medicinal Chemistry Letters  2013 23:1592-1599  DOI:10.1016/j.bmcl.2013.01.109  PMID:23416002
    • Sessions, E. H., Chowdhury, S., Yin, Y., Pocas, J. R., Grant, W., Schroter, T., Lin, L., Ruiz, C., Cameron, M. D., LoGrasso, P., Bannister, T. D., Feng, Y. B. Discovery and optimization of indole and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-II) Bioorganic & Medicinal Chemistry Letters  2011 21:7113-7118  DOI:10.1016/j.bmcl.2011.09.084  PMID:22018789
    • Chowdhury, S., Sessions, E. H., Pocas, J. R., Grant, W., Schroter, T., Lin, L., Ruiz, C., Cameron, M. D., Schurer, S., LoGrasso, P., Bannister, T. D., Feng, Y. B. Discovery and optimization of indoles and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-I) Bioorganic & Medicinal Chemistry Letters  2011 21:7107-7112  DOI:10.1016/j.bmcl.2011.09.083  PMID:22004718
    • Hara, M. R., Kovacs, J. J., Whalen, E. J., Rajagopal, S., Strachan, R. T., Grant, W., Towers, A. J., Williams, B., Lam, C. M., Xiao, K. H., Shenoy, S. K., Gregory, S. G., et al. A stress response pathway regulates DNA damage through beta(2)-adrenoreceptors and beta-arrestin-1 Nature  2011 477:349-353  DOI:10.1038/nature10368  PMID:21857681  PMCID:PMC3628753
    • Fang, X. A., Chen, Y. T., Sessions, E. H., Chowdhury, S., Vojkovsky, T., Yin, Y., Pocas, J. R., Grant, W., Schroter, T., Lin, L., Ruiz, C., Cameron, M. D., et al. Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors Bioorganic & Medicinal Chemistry Letters  2011 21:1844-1848  DOI:10.1016/j.bmcl.2011.01.039  PMID:21349713
    • Chen, Y. T., Vojkovsky, T., Fang, X. G., Pocas, J. R., Grant, W., Handy, A. M. W., Schroter, T., LoGrasso, P., Bannister, T. D., Fang, Y. B. Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors MedChemComm  2011 2:73-75  DOI:10.1039/c0md00194e
    • Fang, X. G., Yin, Y., Chen, Y. T., Yao, L., Wang, B., Cameron, M. D., Lin, L., Khan, S., Ruiz, C., Schroter, T., Grant, W., Weiser, A., et al. Tetrahydroisoquinoline derivatives as highly selective and potent Rho kinase inhibitors Journal of Medicinal Chemistry  2010 53:5727-5737  DOI:10.1021/jm100579r  PMID:20684608
    • Yin, Y., Cameron, M. D., Lin, L., Khan, S., Schroter, T., Grant, W., Pocas, J., Chen, Y. T., Schurer, S., Pachori, A., LoGrasso, P., Feng, Y. B. Discovery of potent and selective urea-based ROCK inhibitors and their effects on intraocular pressure in rats ACS Medicinal Chemistry Letters  2010 1:175-179  DOI:10.1021/ml1000382  PMID:24900192  PMCID:PMC4007833
    • Yin, Y., Lin, L., Ruiz, C., Cameron, M. D., Pocas, J., Grant, W., Schroter, T., Chen, W. M., Duckett, D., Schurer, S., LoGrasso, P., Feng, Y. B. Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors Bioorganic & Medicinal Chemistry Letters  2009 19:6686-6690  DOI:10.1016/j.bmcl.2009.09.115  PMID:19837589

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