recent publications

• academic article

  • Pepys, M. B., Herbert, J., Hutchinson, W. L., Tennent, G. A., Lachmann, H. J., Gallimore, J. R., Lovat, L. B., Bartfai, T., Alanine, A., Hertel, C., Hoffmann, T., Jakob-Roetne, R., et al. Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis Nature  2002 417:254-259  DOI:10.1038/417254a  PMID:12015594
  • Hoffmann, T., Zhong, G. F., List, B., Shabat, D., Anderson, J., Gramatikova, S., Lerner, R. A., Barbas, C. F. Aldolase antibodies of remarkable scope Journal of the American Chemical Society  1998 120:2768-2779  DOI:10.1021/ja973676b
  • Barbas, C. F., Heine, A., Zhong, G. F., Hoffmann, T., Gramatikova, S., Bjornestedt, R., List, B., Anderson, J., Stura, E. A., Wilson, I. A., Lerner, R. A. Immune versus natural selection: Antibody aldolases with enzymic rates but broader scope Science  1997 278:2085-2092  DOI:10.1126/science.278.5346.2085  PMID:9405338
  • Zhong, G. F., Hoffmann, T., Lerner, R. A., Danishefsky, S., Barbas, C. F. Antibody-catalyzed enantioselective robinson annulation Journal of the American Chemical Society  1997 119:8131-8132  DOI:10.1021/ja970944x
  • Weiss, H. J., Hoffmann, T., Yoshioka, A., Ruggeri, Z. M. Evidence that the Arg1744 Gly1745 Asp1746 sequence in the GPIIb-IIIa-binding domain of von Willebrand factor is involved in platelet adhesion and thrombus formation on subendothelium Journal of Laboratory and Clinical Medicine  1993 122:324-332  PMID:8409708
  • Weiss, H. J., Hawiger, J., Ruggeri, Z. M., Turitto, V. T., Thiagarajan, P., Hoffmann, T. Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate Journal of Clinical Investigation  1989 83:288-297  DOI:10.1172/jci113871  PMID:2910912  PMCID:PMC303673