recent publications

• academic article

  • Yuen, M., Sandaradura, S. A., Dowling, J. J., Kostyukova, A. S., Moroz, N., Quinlan, K. G., Lehtokari, V. L., Ravenscroft, G., Todd, E. J., Ceyhan-Birsoy, O., Gokhin, D. S., Maluenda, J., et al. Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy Journal of Clinical Investigation  2014 124:4693-4708  DOI:10.1172/jci75199  PMID:25250574
  • Fritz-Six, K. L., Cox, P. R., Fischer, R. S., Xu, B. S., Gregorio, C. C., Zoghbi, H. Y., Fowler, V. M. Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality Journal of Cell Biology  2003 163:1033-1044  DOI:10.1083/jcb.200308164  PMID:14657235  PMCID:PMC2173615
  • Mudry, R. E., Perry, C. N., Richards, M., Fowler, V. M., Gregorio, C. C. The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes Journal of Cell Biology  2003 162:1057-1068  DOI:10.1083/jcb.200305031  PMID:12975349  PMCID:PMC2172850
  • Knoll, R., Hoshijima, M., Hoffman, H. M., Person, V., Lorenzen-Schmidt, I., Bang, M. L., Hayashi, T., Shiga, N., Yasukawa, H., Schaper, W., McKenna, W., Yokoyama, M., et al. The cardiac mechanical stretch sensor machinery involves a z disc complex that is defective in a subset of human dilated cardiomyopathy Cell  2002 111:943-955  DOI:10.1016/s0092-8674(02)01226-6  PMID:12507422
  • McElhinny, A. S., Kolmerer, B., Fowler, V. M., Labeit, S., Gregorio, C. C. The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments Journal of Biological Chemistry  2001 276:583-592  PMID:11016930
  • Almenar-Queralt, A., Gregorio, C. C., Fowler, V. M. Tropomodulin assembles early in myofibrillogenesis in chick skeletal muscle: evidence that thin filaments rearrange to form striated myofibrils Journal of Cell Science  1999 112:1111-1123  PMID:10085247
  • Gregorio, C. C., Fowler, V. M. Tropomodulin function and thin filament assembly in cardiac myocytes Trends in Cardiovascular Medicine  1996 6:136-141  DOI:10.1016/1050-1738(96)00022-9  PMID:21232287
  • Gregorio, C. C., Fowler, V. M. Mechanisms of thin filament assembly in embryonic chick cardiac myocytes: tropomodulin requires tropomyosin for assembly Journal of Cell Biology  1995 129:683-695  DOI:10.1083/jcb.129.3.683  PMID:7730404  PMCID:PMC2120443
  • Gregorio, C. C., Weber, A., Bondad, M., Pennise, C. R., Fowler, V. M. Requirement of pointed-end capping by tropomodulin to maintain actin filament length in embryonic chick cardiac myocytes Nature  1995 377:83-86  DOI:10.1038/377083a0  PMID:7544875
  • Gregorio, C. C., Repasky, E. A., Fowler, V. M., Black, J. D. Dynamic properties of ankyrin in T lymphocytes: colocalization with spectrin and protein kinase C beta Journal of Cell Biology  1994 125:345-358  DOI:10.1083/jcb.125.2.345  PMID:8163551  PMCID:PMC2120020