recent publications

• academic article

  • Chen, R. Q., Yang, Q. K., Chen, Y. L., Oliveira, V. A., Dalton, W. S., Fearns, C., Lee, J. D. Kinome siRNA screen identifies SMG-1 as a negative regulator of hypoxia-inducible factor-1alpha in hypoxia Journal of Biological Chemistry  2009 284:16752-16758  DOI:10.1074/jbc.M109.014316  PMID:19406746  PMCID:PMC2719310
  • Chen, Y. L., Lu, B. W., Yang, Q. K., Fearns, C., Yates, J. R., Lee, J. D. Combined integrin phosphoproteomic analyses and small interfering RNA-based functional screening identify key regulators for cancer cell adhesion and migration Cancer Research  2009 69:3713-3720  DOI:10.1158/0008-5472.can-08-2515  PMID:19351860  PMCID:PMC2669841
  • Chen, R. Q., Yang, Q. K., Lu, B. W., Yi, W., Cantin, G., Chen, Y. L., Fearns, C., Yates, J. R., Lee, J. D. CDC25B mediates rapamycin-induced oncogenic responses in cancer cells Cancer Research  2009 69:2663-2668  DOI:10.1158/0008-5472.can-08-3222  PMID:19276368  PMCID:PMC2697620
  • Elbrecht, A., Chen, Y. L., Adams, A., Berger, J., Griffin, P., Klatt, T., Zhang, B., Menke, J., Zhou, G. C., Smith, R. G., Moller, D. E. L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma. The role of Cys313 in ligand binding Journal of Biological Chemistry  1999 274:7913-7922  DOI:10.1074/jbc.274.12.7913  PMID:10075686