recent publications

• academic article

  • Leibowitz, M. D., Fievet, C., Hennuyer, N., Peinado-Onsurbe, J., Duez, H., Berger, J., Cullinan, C. A., Sparrow, C. P., Baffic, J., Berger, G. D., Santini, C., Marquis, R. W., et al. Activation of PPARdelta alters lipid metabolism in db/db mice FEBS Letters  2000 473:333-336  DOI:10.1016/s0014-5793(00)01554-4  PMID:10818235
  • Johnson, B. A., Wilson, E. M., Li, Y., Moller, D. E., Smith, R. G., Zhou, G. C. Ligand-induced stabilization of PPARgamma monitored by NMR spectroscopy: implications for nuclear receptor activation Journal of Molecular Biology  2000 298:187-194  DOI:10.1006/jmbi.2000.3636  PMID:10764590
  • Zhang, B., Salituro, G., Szalkowski, D., Li, Z. H., Zhang, Y., Royo, I., Vilella, D., Diez, M. T., Pelaez, F., Ruby, C., Kendall, R. L., Mao, X. Z., et al. Discovery of a small molecule insulin mimetic with antidiabetic activity in mice Science  1999 284:974-977  DOI:10.1126/science.284.5416.974  PMID:10320380
  • Elbrecht, A., Chen, Y. L., Adams, A., Berger, J., Griffin, P., Klatt, T., Zhang, B., Menke, J., Zhou, G. C., Smith, R. G., Moller, D. E. L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma. The role of Cys313 in ligand binding Journal of Biological Chemistry  1999 274:7913-7922  DOI:10.1074/jbc.274.12.7913  PMID:10075686
  • Berger, J., Leibowitz, M. D., Doebber, T. W., Elbrecht, A., Zhang, B., Zhou, G. C., Biswas, C., Cullinan, C. A., Hayes, N. S., Li, Y., Tanen, M., Ventre, J., et al. Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects Journal of Biological Chemistry  1999 274:6718-6725  DOI:10.1074/jbc.274.10.6718  PMID:10037770
  • Zhou, G. C., Cummings, R., Li, Y., Mitra, S., Wilkinson, H. A., Elbrecht, A., Hermes, J. D., Schaeffer, J. M., Smith, R. G., Moller, D. E. Nuclear receptors have distinct affinities for coactivators: characterization by fluorescence resonance energy transfer Molecular Endocrinology  1998 12:1594-1604  DOI:10.1210/me.12.10.1594  PMID:9773982
  • Ding, V. D. H., Moller, D. E., Feeney, W. P., Didolkar, V., Nakhla, A. M., Rhodes, L., Rosner, W., Smith, R. G. Sex hormone-binding globulin mediates prostate androgen receptor action via a novel signaling pathway Endocrinology  1998 139:213-218  DOI:10.1210/en.139.1.213  PMID:9421417