recent publications

• academic article

  • Schleicher, K. D., Sasaki, Y., Tam, A., Kato, D., Duncan, K. K., Boger, D. L. Total synthesis and evaluation of vinblastine analogues containing systematic deep-seated modifications in the vindoline subunit ring system: Core redesign Journal of Medicinal Chemistry  2013 56:483-495  DOI:10.1021/jm3014376  PMID:23252481  PMCID:PMC3554876
  • Tam, A., Gotoh, H., Robertson, W. M., Boger, D. L. Catharanthine C16 substituent effects on the biomimetic coupling with vindoline: preparation and evaluation of a key series of vinblastine analogues Bioorganic & Medicinal Chemistry Letters  2010 20:6408-6410  DOI:10.1016/j.bmcl.2010.09.091  PMID:20932748  PMCID:PMC2957881
  • Ishikawa, H., Colby, D. A., Seto, S., Va, P., Tam, A., Kakei, H., Rayl, T. J., Hwang, I., Boger, D. L. Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues Journal of the American Chemical Society  2009 131:4904-4916  DOI:10.1021/ja809842b  PMID:19292450  PMCID:PMC2727944