recent publications
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academic article
- Tang, B., Becanovic, K., Desplats, P. A., Spencer, B., Hill, A. M., Connolly, C., Masliah, E., Leavitt, B. R., Thomas, E. A. Forkhead box protein p1 is a transcriptional repressor of immune signaling in the cns: Implications for transcriptional dysregulation in huntington disease Human Molecular Genetics 2012 21:3097-3111 DOI:10.1093/hmg/dds132 PMID:22492998 PMCID:PMC3384380
- Denny, C. A., Desplats, P. A., Thomas, E. A., Seyfried, T. N. Cerebellar lipid differences between r6/1 transgenic mice and humans with huntington's disease Journal of Neurochemistry 2010 115:748-758 DOI:10.1111/j.1471-4159.2010.06964.x PMID:20731757
- Thomas, E. A., Coppola, G., Desplats, P. A., Tang, B., Soragni, E., Burnett, R., Gao, F. Y., Fitzgerald, K. M., Borok, J. F., Herman, D., Geschwind, D. H., Gottesfeld, J. M. The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice Proceedings of the National Academy of Sciences of the United States of America 2008 105:15564-15569 DOI:10.1073/pnas.0804249105 PMID:18829438 PMCID:PMC2563081
- Desplats, P. A., Lambert, J. R., Thomas, E. A. Functional roles for the striatal-enriched transcription factor, bcl11b, in the control of striatal gene expression and transcriptional dysregulation in huntington's disease Neurobiology of Disease 2008 31:298-308 DOI:10.1016/j.nbd.2008.05.005 PMID:18595722 PMCID:PMC2569875
- Desplats, P. A., Denny, C. A., Kass, K. E., Gilmartin, T., Head, S. R., Sutcliffe, J. G., Seyffied, T. N., Thomas, E. A. Glycolipid and ganglioside metabolism imbalances in huntington's disease Neurobiology of Disease 2007 27:265-277 DOI:10.1016/j.nbd.2007.05.003 PMID:17600724 PMCID:PMC2082128
- Desplats, P. A., Kass, K. E., Gilmartin, T., Stanwood, G. D., Woodward, E. L., Head, S. R., Sutcliffe, J. G., Thomas, E. A. Selective deficits in the expression of striatal-enriched mrnas in huntington's disease Journal of Neurochemistry 2006 96:743-757 DOI:10.1111/j.1471-4159.2005.03588.x PMID:16405510