recent publications

• academic article

  • Tang, B., Becanovic, K., Desplats, P. A., Spencer, B., Hill, A. M., Connolly, C., Masliah, E., Leavitt, B. R., Thomas, E. A. Forkhead box protein p1 is a transcriptional repressor of immune signaling in the cns: Implications for transcriptional dysregulation in huntington disease Human Molecular Genetics  2012 21:3097-3111  DOI:10.1093/hmg/dds132  PMID:22492998  PMCID:PMC3384380
  • Denny, C. A., Desplats, P. A., Thomas, E. A., Seyfried, T. N. Cerebellar lipid differences between r6/1 transgenic mice and humans with huntington's disease Journal of Neurochemistry  2010 115:748-758  DOI:10.1111/j.1471-4159.2010.06964.x  PMID:20731757
  • Thomas, E. A., Coppola, G., Desplats, P. A., Tang, B., Soragni, E., Burnett, R., Gao, F. Y., Fitzgerald, K. M., Borok, J. F., Herman, D., Geschwind, D. H., Gottesfeld, J. M. The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice Proceedings of the National Academy of Sciences of the United States of America  2008 105:15564-15569  DOI:10.1073/pnas.0804249105  PMID:18829438  PMCID:PMC2563081
  • Desplats, P. A., Lambert, J. R., Thomas, E. A. Functional roles for the striatal-enriched transcription factor, bcl11b, in the control of striatal gene expression and transcriptional dysregulation in huntington's disease Neurobiology of Disease  2008 31:298-308  DOI:10.1016/j.nbd.2008.05.005  PMID:18595722  PMCID:PMC2569875
  • Desplats, P. A., Denny, C. A., Kass, K. E., Gilmartin, T., Head, S. R., Sutcliffe, J. G., Seyffied, T. N., Thomas, E. A. Glycolipid and ganglioside metabolism imbalances in huntington's disease Neurobiology of Disease  2007 27:265-277  DOI:10.1016/j.nbd.2007.05.003  PMID:17600724  PMCID:PMC2082128
  • Desplats, P. A., Kass, K. E., Gilmartin, T., Stanwood, G. D., Woodward, E. L., Head, S. R., Sutcliffe, J. G., Thomas, E. A. Selective deficits in the expression of striatal-enriched mrnas in huntington's disease Journal of Neurochemistry  2006 96:743-757  DOI:10.1111/j.1471-4159.2005.03588.x  PMID:16405510