recent publications
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academic article
- Wang, C., Wu, H., Evron, T., Vardy, E., Han, G. W., Huang, X. P., Hufeisen, S. J., Mangano, T. J., Urban, D. J., Katritch, V., Cherezov, V., Caron, M. G., et al. Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs Nature Communications 2014 5:4355 DOI:10.1038/ncomms5355 PMID:25008467 PMCID:PMC4198951
- Vardy, E., Mosier, P. D., Frankowski, K. J., Wu, H., Katritch, V., Westkaemper, R. B., Aube, J., Stevens, R. C., Roth, B. L. Chemotype-selective modes of action of κ-opioid receptor agonists Journal of Biological Chemistry 2013 288:34470-34483 DOI:10.1074/jbc.M113.515668 PMID:24121503 PMCID:PMC3843062
- Wang, C., Jiang, Y., Ma, J., Wu, H., Wacker, D., Katritch, V., Han, G. W., Liu, W., Huang, X. P., Vardy, E., McCorvy, J. D., Gao, X., et al. Structural basis for molecular recognition at serotonin receptors Science 2013 340:610-614 DOI:10.1126/science.1232807 PMID:23519210 PMCID:PMC3644373
- Wacker, D., Wang, C., Katritch, V., Han, G. W., Huang, X. P., Vardy, E., McCorvy, J. D., Jiang, Y., Chu, M., Siu, F. Y., Liu, W., Xu, H. E., et al. Structural features for functional selectivity at serotonin receptors Science 2013 340:615-619 DOI:10.1126/science.1232808 PMID:23519215 PMCID:PMC3644390
- Wu, H. X., Wacker, D., Mileni, M., Katritch, V., Han, G. W., Vardy, E., Liu, W., Thompson, A. A., Huang, X. P., Carroll, F. I., Mascarella, S. W., Westkaemper, R. B., et al. Structure of the human κ-opioid receptor in complex with JDTic Nature 2012 485:327-332 DOI:10.1038/nature10939 PMID:22437504 PMCID:PMC3356457
- Thompson, A. A., Liu, W., Chun, E., Katritch, V., Wu, H. X., Vardy, E., Huang, X. P., Trapella, C., Guerrini, R., Calo, G., Roth, B. L., Cherezov, V., et al. Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic Nature 2012 485:395-399 DOI:10.1038/nature11085 PMID:22596163 PMCID:PMC3356928