recent publications

• academic article

  • Chen, L., Kwon, Y. D., Zhou, T. Q., Wu, X. L., O'Dell, S., Cavacini, L., Hessell, A. J., Pancera, M., Tang, M., Xu, L., Yang, Z. Y., Zhang, M. Y., et al. Structural basis of immune evasion at the site of cd4 attachment on hiv-1 gp120 Science  2009 326:1123-1127  DOI:10.1126/science.1175868  PMID:19965434  PMCID:PMC2862588
  • Zhou, T. Q., Xu, L., Dey, B., Hessell, A. J., Van Ryk, D., Xiang, S. H., Yang, X., Zhang, M. Y., Zwick, M. B., Arthos, J., Burton, D. R., Dimitrov, D. S., et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120 Nature  2007 445:732-737  DOI:10.1038/nature05580  PMID:17301785  PMCID:PMC2584968
  • Huang, C. C., Tang, M., Zhang, M. Y., Majeed, S., Montabana, E., Stanfield, R. L., Dimitrov, D. S., Korber, B., Sodroski, J., Wilson, I. A., Wyatt, R., Kwong, P. D. Structure of a v3-containing hiv-1 gp120 core Science  2005 310:1025-1028  DOI:10.1126/science.1118398  PMID:16284180  PMCID:PMC2408531
  • Darbha, R., Phogat, S., Labrijn, A. F., Shu, Y., Gu, Y. J., Andrykovitch, M., Zhang, M. Y., Pantophlet, R., Martin, L., Vita, C., Burton, D. R., Dimitrov, D. S., et al. Crystal structure of the broadly cross-reactive hiv-1-neutralizing fab x5 and fine mapping of its epitope Biochemistry  2004 43:1410-1417  DOI:10.1021/bi035323x  PMID:14769016
  • Zhang, M. Y., Xiao, X. D., Sidorov, I. A., Choudhry, V., Cham, F., Zhang, P. F., Bouma, P., Zwick, M., Choudhary, A., Montefiori, D. C., Broder, C. C., Burton, D. R., et al. Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody Journal of Virology  2004 78:9233-9242  DOI:10.1128/jvi.78.17.9233-9242.2004  PMID:15308718
  • Zhang, M. Y., Shu, Y. U., Rudolph, D., Prabakaran, P., Labrijn, A. F., Zwick, M. B., Lal, R. B., Dimitrov, D. S. Improved breadth and potency of an hiv-1-neutralizing human single-chain antibody by random mutagenesis and sequential antigen panning Journal of Molecular Biology  2004 335:209-219  DOI:10.1016/j.jmb.2003.09.055  PMID:14659751
  • Huang, C. C., Venturi, M., Majeed, S., Moore, M. J., Phogat, S., Zhang, M. Y., Dimitrov, D. S., Hendrickson, W. A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., et al. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proceedings of the National Academy of Sciences of the United States of America  2004 101:2706-2711  DOI:10.1073/pnas.0308527100  PMID:14981267  PMCID:PMC365685
  • Labrijn, A. F., Poignard, P., Raja, A., Zwick, M. B., Delgado, K., Franti, M., Binley, J., Vivona, V., Grundner, C., Huang, C. C., Venturi, M., Petropoulos, C. J., et al. Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gpl120 is sterically restricted on primary human immunodeficiency virus type 1 Journal of Virology  2003 77:10557-10565  DOI:10.1128/jvi.77.19.10557-10565.2003  PMID:12970440
  • Moulard, M., Phogat, S. K., Shu, Y., Labrijn, A. F., Xiao, X. D., Binley, J. M., Zhang, M. Y., Sidorov, I. A., Broder, C. C., Robinson, J., Parren, Pwhi, Burton, D. R., et al. Broadly cross-reactive hiv-1-neutralizing human monoclonal fab selected for binding to gp120-cd4-ccr5 complexes Proceedings of the National Academy of Sciences of the United States of America  2002 99:6913-6918  DOI:10.1073/pnas.102562599  PMID:11997472  PMCID:PMC124503