recent publications

• academic article

  • Chowdhury, S., Ketcham, S. A., Schroer, T. A., Lander, G. C. Structural organization of the dynein-dynactin complex bound to microtubules Nature Structural & Molecular Biology  2015 22:345-347  DOI:10.1038/nsmb.2996  PMID:25751425  PMCID:PMC4385409
  • Gardner, B. M., Chowdhury, S., Lander, G. C., Martin, A. The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits Journal of Molecular Biology  2015 427:1375-1388  DOI:10.1016/j.jmb.2015.01.019  PMID:25659908  PMCID:PMC4355278
  • Yin, Z. J., Comellas-Aragones, M., Chowdhury, S., Bentley, P., Kaczanowska, K., BenMohamed, L., Gildersleeve, J. C., Finn, M. G., Huang, X. Boosting immunity to small tumor-associated carbohydrates with bacteriophage Qβ capsids ACS Chemical Biology  2013 8:1253-1262  DOI:10.1021/cb400060x  PMID:23505965  PMCID:PMC3735802
  • Chowdhury, S., Chen, Y. T., Fang, X. G., Grant, W., Pocas, J., Cameron, M. D., Ruiz, C., Lin, L., Park, H., Schroter, T., Bannister, T. D., LoGrasso, P. V., et al. Amino acid derived quinazolines as Rock/PKA inhibitors Bioorganic & Medicinal Chemistry Letters  2013 23:1592-1599  DOI:10.1016/j.bmcl.2013.01.109  PMID:23416002
  • Sessions, E. H., Chowdhury, S., Yin, Y., Pocas, J. R., Grant, W., Schroter, T., Lin, L., Ruiz, C., Cameron, M. D., LoGrasso, P., Bannister, T. D., Feng, Y. B. Discovery and optimization of indole and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-II) Bioorganic & Medicinal Chemistry Letters  2011 21:7113-7118  DOI:10.1016/j.bmcl.2011.09.084  PMID:22018789
  • Chowdhury, S., Sessions, E. H., Pocas, J. R., Grant, W., Schroter, T., Lin, L., Ruiz, C., Cameron, M. D., Schurer, S., LoGrasso, P., Bannister, T. D., Feng, Y. B. Discovery and optimization of indoles and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-I) Bioorganic & Medicinal Chemistry Letters  2011 21:7107-7112  DOI:10.1016/j.bmcl.2011.09.083  PMID:22004718
  • Bialkowska, A. B., Crisp, M., Bannister, T., He, Y. J., Chowdhury, S., Schurer, S., Chase, P., Spicer, T., Madoux, F., Tian, C. L., Hodder, P., Zaharevitz, D., et al. Identification of small-molecule inhibitors of the colorectal cancer oncogene Kruppel-like factor 5 expression by ultrahigh-throughput screening Molecular Cancer Therapeutics  2011 10:2043-2051  DOI:10.1158/1535-7163.mct-11-0550  PMID:21885866  PMCID:PMC3213326
  • Fang, X. A., Chen, Y. T., Sessions, E. H., Chowdhury, S., Vojkovsky, T., Yin, Y., Pocas, J. R., Grant, W., Schroter, T., Lin, L., Ruiz, C., Cameron, M. D., et al. Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors Bioorganic & Medicinal Chemistry Letters  2011 21:1844-1848  DOI:10.1016/j.bmcl.2011.01.039  PMID:21349713
  • Sessions, E. H., Smolinski, M., Wang, B., Frackowiak, B., Chowdhury, S., Yin, Y., Chen, Y. T., Ruiz, C., Lin, L., Pocas, J., Schroter, T., Cameron, M. D., et al. The development of benzimidazoles as selective Rho kinase inhibitors Bioorganic & Medicinal Chemistry Letters  2010 20:1939-1943  DOI:10.1016/j.bmcl.2010.01.124  PMID:20167489
  • Shepherd, J. D., Rumbaugh, G., Wu, J., Chowdhury, S., Plath, N., Kuhl, D., Huganir, R. L., Worley, P. F. Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors Neuron  2006 52:475-484  DOI:10.1016/j.neuron.2006.08.034  PMID:17088213  PMCID:PMC1764219

• report

  • Bialkowska, A., Crisp, M., Madoux, F., Spicer, T., Knapinska, A., Mercer, B., Bannister, T. D., He, Y., Chowdhury, S., Cameron, M., Yang, V. W., Hodder, P. ML264: An antitumor agent that potently and selectively inhibits kruppel-like factor five (KLF5) expression: a probe for studying colon cancer development and progression Probe Reports from the NIH Molecular Libraries Program. 2010  PMID:23762940