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DNA-induced alpha-helix capping in conserved linker sequences is a determinant of binding affinity in Cys(2)-His(2) zinc fingers

Academic Article
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Overview

authors

  • Laity, J. H.
  • Dyson, Jane
  • Wright, Peter

publication date

  • January 2000

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Amino Acid Sequence
  • Binding Sites
  • Conserved Sequence
  • Crystallography, X-Ray
  • Cysteine
  • DNA
  • DNA-Binding Proteins
  • Histidine
  • Models, Molecular
  • Molecular Sequence Data
  • Nuclear Magnetic Resonance, Biomolecular
  • Protein Structure, Secondary
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Transcription Factor TFIIIA
  • Transcription Factors
  • WT1 Proteins
  • Zinc Fingers
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Research

keywords

  • DNA binding
  • NMR
  • TFIIIA
  • Wilms' tumor
  • conserved TGEKP linker
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1006/jmbi.1999.3406

PubMed ID

  • 10656784
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Additional Document Info

start page

  • 719

end page

  • 727

volume

  • 295

issue

  • 4

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