recent publications

• academic article

  • Schmitz, R. J., Schultz, M. D., Urich, M. A., Nery, J. R., Pelizzola, M., Libiger, O., Alix, A., McCosh, R. B., Chen, H. M., Schork, N. J., Ecker, J. R. Patterns of population epigenomic diversity Nature  2013 495:193-198  DOI:10.1038/nature11968  PMID:23467092  PMCID:PMC3798000
  • Hazen, S. P., Naef, F., Quisel, T., Gendron, J. M., Chen, H. M., Ecker, J. R., Borevitz, J. O., Kay, S. A. Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays Genome Biology  2009 10:R17  DOI:10.1186/gb-2009-10-2-r17  PMID:19210792  PMCID:PMC2688271
  • Aharoni, A., Thieme, K., Chiu, C. P. C., Buchini, S., Lairson, L. L., Chen, H. M., Strynadka, N. C. J., Wakarchuk, W. W., Withers, S. G. High-throughput screening methodology for the directed evolution of glycosyltransferases Nature Methods  2006 3:609-614  DOI:10.1038/nmeth899  PMID:16862135
  • Zhang, X. M., Odom, D. T., Koo, S. H., Conkright, M. D., Canettieri, G., Best, J., Chen, H. M., Jenner, R., Herbolsheimer, E., Jacobsen, E., Kadam, S., Ecker, J. R., et al. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues Proceedings of the National Academy of Sciences of the United States of America  2005 102:4459-4464  DOI:10.1073/pnas.0501076102  PMID:15753290  PMCID:PMC555478
  • Engelman, A., Liu, Y., Chen, H. M., Farzan, M., Dyda, F. Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase Journal of Virology  1997 71:3507-3514  PMID:9094622  PMCID:PMC191497
  • Chen, H. M., Li, Y. X., Panda, T., Buehler, F., Ford, C., Reilly, P. J. Effect of replacing helical glycine residues with alanines on reversible and irreversible stability and production of aspergillus awamori glucoamylase Protein Engineering  1996 9:499-505  DOI:10.1093/protein/9.6.499  PMID:8862550