Evolutionary analysis of HIV-1 protease inhibitors: methods for design of inhibitors that evade resistance
Academic Article
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Overview
publication date
- 2002
journal
subject areas
- Acquired Immunodeficiency Syndrome
- Binding Sites
- Biological Evolution
- Computational Biology
- Computer Simulation
- Computer-Aided Design
- Drug Design
- Drug Resistance, Viral
- Drug Therapy, Combination
- HIV Protease
- HIV Protease Inhibitors
- HIV-1
- Humans
- Indinavir
- Models, Molecular
- Mutation
- Nelfinavir
- Ritonavir
- Saquinavir