recent publications

• academic article

  • Zhou, T., Lynch, R. M., Chen, L., Acharya, P., Wu, X., Doria-Rose, N. A., Joyce, M. G., Lingwood, D., Soto, C., Bailer, R. T., Ernandes, M. J., Kong, R., et al. Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors Cell  2015 161:1280-1292  DOI:10.1016/j.cell.2015.05.007  PMID:26004070  PMCID:PMC4683157
  • Doria-Rose, N. A., Schramm, C. A., Gorman, J., Moore, P. L., Bhiman, J. N., DeKosky, B. J., Ernandes, M. J., Georgiev, I. S., Kim, H. J., Pancera, M., Staupe, R. P., Altae-Tran, H. R., et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies Nature  2014 509:55-62  DOI:10.1038/nature13036  PMID:24590074  PMCID:PMC4395007
  • Sundling, C., Zhang, Z., Phad, G. E., Sheng, Z., Wang, Y., Mascola, J. R., Li, Y., Wyatt, R. T., Shapiro, L., Hedestam, G. B. K. Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization Journal of Immunology  2014 192:3637-3644  DOI:10.4049/jimmunol.1303334  PMID:24623130  PMCID:PMC3993955
  • Zhu, J., Wu, X., Zhang, B., McKee, K., O'Dell, S., Soto, C., Zhou, T., Casazza, J. P., NISC Comparative Sequencing Program, Mullikin, J. C., Kwong, P. D., Mascola, J. R., et al. De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts Proceedings of the National Academy of Sciences of the United States of America  2013 110:E4088-E4097  DOI:10.1073/pnas.1306262110  PMID:24106303  PMCID:PMC3808619
  • Zhou, T., Zhu, J., Wu, X., Moquin, S., Zhang, B., Acharya, P., Georgiev, I. S., Altae-Tran, H. R., Chuang, G. Y., Joyce, M. G., Kwon, Y. D., Longo, N. S., et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies Immunity  2013 39:245-258  DOI:10.1016/j.immuni.2013.04.012  PMID:23911655  PMCID:PMC3985390
  • Liao, H. X., Lynch, R., Zhou, T., Gao, F., Alam, S. M., Boyd, S. D., Fire, A. Z., Roskin, K. M., Schramm, C. A., Zhang, Z., Zhu, J., Shapiro, L., et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Nature  2013 496:469-476  DOI:10.1038/nature12053  PMID:23552890  PMCID:PMC3637846
  • Zhu, J., Ofek, G., Yang, Y. P., Zhang, B. S., Louder, M. K., Lu, G., McKee, K., Pancera, M., Skinner, J., Zhang, Z. H., Parks, R., Eudailey, J., et al. Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains Proceedings of the National Academy of Sciences of the United States of America  2013 110:6470-6475  DOI:10.1073/pnas.1219320110  PMID:23536288  PMCID:PMC3631616
  • Xu, Q. P., Christen, B., Chiu, H. J., Jaroszewski, L., Klock, H. E., Knuth, M. W., Miller, M. D., Elsliger, M. A., Deacon, A. M., Godzik, A., Lesley, S. A., Figurski, D. H., et al. Structure of the pilus assembly protein TadZ from eubacterium rectale: Implications for polar localization Molecular Microbiology  2012 83:712-727  DOI:10.1111/j.1365-2958.2011.07954.x  PMID:22211578  PMCID:PMC3272108
  • Zhu, J., O'Dell, S., Ofek, G., Pancera, M., Wu, X., Zhang, B., Zhang, Z., NISC Comparative Sequencing Program, Mullikin, J. C., Simek, M., Burton, D. R., Koff, W. C., et al. Somatic populations of PGT135-137 HIV-1-neutralizing antibodies identified by 454 pyrosequencing and bioinformatics Frontiers in Microbiology  2012 3:315  DOI:10.3389/fmicb.2012.00315  PMID:23024643  PMCID:PMC3441199
  • Kwon, Y. D., Finzi, A., Wu, X., Dogo-Isonagie, C., Lee, L. K., Moore, L. R., Schmidt, S. D., Stuckey, J., Yang, Y., Zhou, T., Zhu, J., Vicic, D. A., et al. Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops Proceedings of the National Academy of Sciences of the United States of America  2012 109:5663-5668  DOI:10.1073/pnas.1112391109  PMID:22451932  PMCID:PMC3326499
  • Wu, X. L., Zhou, T. Q., Zhu, J., Zhang, B. S., Georgiev, I., Wang, C., Chen, X. J., Longo, N. S., Louder, M., McKee, K., O'Dell, S., Perfetto, S., et al. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing Science  2011 333:1593-1602  DOI:10.1126/science.1207532  PMID:21835983  PMCID:PMC3516815
  • Zhou, T., Georgiev, I., Wu, X., Yang, Z. Y., Dai, K., Finzi, A., Kwon, Y. D., Scheid, J. F., Shi, W., Xu, L., Yang, Y., Zhu, J., et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01 Science  2010 329:811-817  DOI:10.1126/science.1192819  PMID:20616231  PMCID:PMC2981354
  • Winzeler, E., Wheeler, R., Shapiro, L. Transcriptional analysis of the caulobacter 4.5 s rna ffs gene and the physiological basis of an ffs mutant with a ts phenotype Journal of Molecular Biology  1997 272:665-676  DOI:10.1006/jmbi.1997.1261  PMID:9368649
  • Winzeler, E., Shapiro, L. Translation of the leaderless caulobacter dnax mrna Journal of Bacteriology  1997 179:3981-3988  PMID:9190815  PMCID:PMC179208
  • Winzeler, E., Shapiro, L. A novel promoter motif for caulobacter cell cycle-controlled DNA replication genes Journal of Molecular Biology  1996 264:412-425  DOI:10.1006/jmbi.1996.0650  PMID:8969294
  • Winzeler, E., Shapiro, L. Use of flow-cytometry to identify a caulobacter 4.5 s rna temperature-sensitive mutant defective in the cell-cycle Journal of Molecular Biology  1995 251:346-365  DOI:10.1006/jmbi.1995.0439  PMID:7544413