recent publications

• academic article

  • Horwitz, M. S., Efrat, S., Christen, U., von Herrath, M. G., Oldstone, M. B. A. Adenovirus e3 mhc inhibitory genes but not tnf/fas apoptotic inhibitory genes expressed in beta cells prevent autoimmune diabetes Proceedings of the National Academy of Sciences of the United States of America  2009 106:19450-19454  DOI:10.1073/pnas.0910648106  PMID:19887639  PMCID:PMC2780797
  • Homann, D., Dummer, W., Wolfe, T., Rodrigo, E., Theofilopoulos, A. N., Oldstone, M. B. A., von Herrath, M. G. Lack of intrinsic ctla-4 expression has minimal effect on regulation of antiviral t-cell immunity Journal of Virology  2006 80:270-280  DOI:10.1128/jvi.80.1.270-280.2006  PMID:16352552
  • Fujinami, R. S., von Herrath, M. G., Christen, U., Whitton, J. L. Molecular mimicry, bystander activation, or viral persistence: Infections and autoimmune disease Clinical Microbiology Reviews  2006 19:80-94  DOI:10.1128/cmr.19.1.80-94.2006  PMID:16418524
  • Rhode, A., Pauza, M. E., Barral, A. M., Rodrigo, E., Oldstone, M. B. A., von Herrath, M. G., Christen, U. Islet-specific expression of cxcl10 causes spontaneous islet infiltration and accelerates diabetes development Journal of Immunology  2005 175:3516-3524  PMID:16148094
  • Christen, U., Edelmann, K. H., McGavern, D. B., Wolfe, T., Coon, B., Teague, M. K., Miler, S. D., Oldstone, M. B. A., von Herrath, M. G. A viral epitope that mimics a self antigen can accelerate but nit initiate autoimmune diabetes Journal of Clinical Investigation  2004 114:1290-1298  DOI:10.1172/jci200422557  PMID:15520861
  • Christen, U., Benke, D., Wolfe, T., Rodrigo, E., Rhode, A., Hughes, A. C., Oldstone, M. B. A., von Herrath, M. G. Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient Journal of Clinical Investigation  2004 113:74-84  DOI:10.1172/jci200417005  PMID:14702111  PMCID:PMC300760
  • Christen, U., McGavern, D. B., Luster, A. D., von Herrath, M. G., Oldstone, M. B. A. Among cxcr3 chemokines, ifn-gamma-inducible protein of 10 kda (cxc chemokine ligand (cxcl) 10) but not monokine induced by ifn-gamma (cxcl9) imprints a pattern for the subsequent development of autoimmune disease Journal of Immunology  2003 171:6838-6845  PMID:14662890
  • von Herrath, M. G., Fujinami, R. S., Whitton, J. L. Microorganisms and autoimmunity: Making the barren field fertile? Nature Reviews Microbiology  2003 1:151-157  DOI:10.1038/nrmicro754  PMID:15035044
  • Slifka, M. K., Blattman, J. N., Sourdive, D. J. D., Liu, F., Huffman, D. L., Wolfe, T., Hughes, A., Oldstone, M. B. A., Ahmed, R., von Herrath, M. G. Preferential escape of subdominant cd8(+) t cells during negative selection results in an altered antiviral t cell hierarchy Journal of Immunology  2003 170:1231-1239  PMID:12538681
  • Hudrisier, D., Riond, J., Burlet-Schiltz, O., von Herrath, M. G., Lewicki, H., Monsarrat, B., Oldstone, M. B. A., Gairin, J. E. Structural and functional identification of major histocompatibility complex class i-restricted self-peptides as naturally occurring molecular mimics of viral antigens - possible role in cd8(+) t cell-mediated, virus-induced autoimmune disease Journal of Biological Chemistry  2001 276:19396-19403  DOI:10.1074/jbc.M008864200  PMID:11278441
  • von Herrath, M. G., Berger, D. P., Homann, D., Tishon, T., Sette, A., Oldstone, M. B. A. Vaccination to treat persistent viral infection Virology  2000 268:411-419  DOI:10.1006/viro.1999.0130  PMID:10704349
  • Coon, B., An, L. L., Whitton, J. L., von Herrath, M. G. DNA immunization to prevent autoimmune diabetes Journal of Clinical Investigation  1999 104:189-194  DOI:10.1172/jci7209  PMID:10411548
  • Homann, D., Dyrberg, T., Petersen, J., Oldstone, M. B. A., von Herrath, M. G. Insulin in oral immune "tolerance": A one-amino acid change in the b chain makes the difference Journal of Immunology  1999 163:1833-1838  PMID:10438916
  • Homann, D., Tishon, A., Berger, D. P., Weigle, W. O., von Herrath, M. G., Oldstone, M. B. A. Evidence for an underlying cd4 helper and cd8 t-cell defect in b-cell-deficient mice: Failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from mu mt/mu mt mice Journal of Virology  1998 72:9208-9216  PMID:9765468  PMCID:PMC110340
  • von Herrath, M. G., Coon, B., Lewicki, H., Mazarguil, H., Gairin, J. E., Oldstone, M. B. A. In vivo treatment with a mhc class i-restricted blocking peptide can prevent virus-induced autoimmune diabetes Journal of Immunology  1998 161:5087-5096  PMID:9794447
  • von Herrath, M. G., Holz, A., Homann, D., Oldstone, M. B. A. Role of viruses in type i diabetes Seminars in Immunology  1998 10:87-100  DOI:10.1006/smim.1997.0108  PMID:9529659