recent publications

• academic article

  • Adibekian, A., Martin, B. R., Chang, J. W., Hsu, K. L., Tsuboi, K., Bachovchin, D. A., Speers, A. E., Brown, S. J., Spicer, T., Fernandez-Vega, V., Ferguson, J., Hodder, P. S., et al. Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes Journal of the American Chemical Society  2012 134:10345-10348  DOI:10.1021/ja303400u  PMID:22690931  PMCID:PMC3392194
  • Li, Y., Martin, B. R., Cravatt, B. F., Hofmann, S. L. Dhhc5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells Journal of Biological Chemistry  2012 287:523-530  DOI:10.1074/jbc.M111.306183  PMID:22081607  PMCID:PMC3249106
  • Martin, B. R., Wang, C., Adibekian, A., Tully, S. E., Cravatt, B. F. Global profiling of dynamic protein palmitoylation Nature Methods  2012 9:84-89  DOI:10.1038/nmeth.1769  PMID:22056678  PMCID:PMC3248616
  • Adibekian, A., Martin, B. R., Wang, C., Hsu, K. L., Bachovchin, D. A., Niessen, S., Hoover, H., Cravatt, B. F. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors Nature Chemical Biology  2011 7:469-478  DOI:10.1038/nchembio.579  PMID:21572424  PMCID:PMC3118922
  • Martin, B. R., Cravatt, B. F. Large-scale profiling of protein palmitoylation in mammalian cells Nature Methods  2009 6:135-138  DOI:10.1038/nmeth.1293  PMID:19137006  PMCID:PMC2775068
  • Wise, L. E., Shelton, C. C., Cravatt, B. F., Martin, B. R., Lichtman, A. H. Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors European Journal of Pharmacology  2007 557:44-48  DOI:10.1016/j.ejphar.2006.11.002  PMID:17217945
  • Naidu, P. S., Varvel, S. A., Ahn, K., Cravatt, B. F., Martin, B. R., Lichtman, A. H. Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality Psychopharmacology  2007 192:61-70  DOI:10.1007/s00213-006-0689-4  PMID:17279376
  • Cravatt, B. F., Demarest, K., Patricelli, M. P., Bracey, M. H., Giang, D. K., Martin, B. R., Lichtman, A. H. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase Proceedings of the National Academy of Sciences of the United States of America  2001 98:9371-9376  DOI:10.1073/pnas.161191698  PMID:11470906  PMCID:PMC55427

• report

  • Adibekian, A., Martin, B. R., Chang, J. W., Hsu, K. L., Tsuboi, K., Bachovchin, D. A., Speers, A. E., Brown, S. J., Spicer, T., Fernandez-Vega, V., Ferguson, J., Cravatt, B. F., et al. Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2) Probe Reports from the NIH Molecular Libraries Program. 2010  PMID:24624468
  • Adibekian, A., Martin, B. R., Chang, J. W., Hsu, K. L., Tsuboi, K., Bachovchin, D. A., Speers, A. E., Brown, S. J., Spicer, T., Fernandez-Vega, V., Ferguson, J., Cravatt, B. F., et al. Characterization of a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) Probe Reports from the NIH Molecular Libraries Program. 2010  PMID:24624465
  • Adibekian, A., Martin, B. R., Speers, A. E., Brown, S. J., Spicer, T., Fernandez-Vega, V., Ferguson, J., Cravatt, B. F., Hodder, P., Rosen, H. Optimization and characterization of a triazole urea dual inhibitor for lysophospholipase 1 (LYPLA1) and lysophospholipase 2 (LYPLA2) Probe Reports from the NIH Molecular Libraries Program. 2010  PMID:23658947