recent publications

• academic article

  • Macauley, M. S., Pfrengle, F., Rademacher, C., Nycholat, C. M., Gale, A. J., von Drygalski, A., Paulson, J. C. Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis Journal of Clinical Investigation  2013 123:3074-3083  DOI:10.1172/jci69187  PMID:23722906  PMCID:PMC3706185
  • Xu, R., de Vries, R. P., Zhu, X., Nycholat, C. M., McBride, R., Yu, W., Paulson, J. C., Wilson, I. A. Preferential recognition of avian-like receptors in human influenza A H7N9 viruses Science  2013 342:1230-1235  DOI:10.1126/science.1243761  PMID:24311689  PMCID:PMC3954636
  • Nycholat, C. M., Peng, W., McBride, R., Antonopoulos, A., de Vries, R. P., Polonskaya, Z., Finn, M. G., Dell, A., Haslam, S. M., Paulson, J. C. Synthesis of biologically active N- and O-linked glycans with multisialylated poly-N-acetyllactosamine extensions using P. damsela α2-6 sialyltransferase Journal of the American Chemical Society  2013 135:18280-18283  DOI:10.1021/ja409781c  PMID:24256304  PMCID:PMC3901641
  • Kawasaki, N., Vela, J. L., Nycholat, C. M., Rademacher, C., Khurana, A., van Rooijen, N., Crocker, P. R., Kronenberg, M., Paulson, J. C. Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation Proceedings of the National Academy of Sciences of the United States of America  2013 110:7826-7831  DOI:10.1073/pnas.1219888110  PMID:23610394  PMCID:PMC3651435
  • Rademacher, C., Bru, T., McBride, R., Robison, E., Nycholat, C. M., Kremer, E. J., Paulson, J. C. A siglec-like sialic-acid-binding motif revealed in an adenovirus capsid protein Glycobiology  2012 22:1086-1091  DOI:10.1093/glycob/cws073  PMID:22522600  PMCID:PMC3382346
  • Chen, W. H. C., Kawasaki, N., Nycholat, C. M., Han, S. F., Pilotte, J., Crocker, P. R., Paulson, J. C. Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/cd169 PLoS One  2012 7:e39039  DOI:10.1371/journal.pone.0039039  PMID:22723922  PMCID:PMC3378521
  • Xu, R., Zhu, X. Y., McBride, R., Nycholat, C. M., Yu, W. L., Paulson, J. C., Wilson, I. A. Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 h1n1 influenza pandemic Journal of Virology  2012 86:9221-9232  DOI:10.1128/jvi.00697-12  PMID:22718832  PMCID:PMC3416152
  • Nycholat, C. M., Rademacher, C., Kawasaki, N., Paulson, J. C. In silica-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages Journal of the American Chemical Society  2012 134:15696-15699  DOI:10.1021/ja307501e  PMID:22967315  PMCID:PMC3462166
  • Zhu, X. Y., McBride, R., Nycholat, C. M., Yu, W. L., Paulson, J. C., Wilson, I. A. Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic acid receptors Journal of Virology  2012 86:13371-13383  DOI:10.1128/jvi.01426-12  PMID:23015718  PMCID:PMC3503043
  • Nycholat, C. M., McBride, R., Ekiert, D. C., Xu, R., Rangarajan, J., Peng, W. J., Razi, N., Gilbert, M., Wakarchuk, W., Wilson, I. A., Paulson, J. C. Recognition of sialylated poly-n-acetyllactosamine chains on n- and o-linked glycans by human and avian influenza a virus hemagglutinins Angewandte Chemie-International Edition  2012 51:4860-4863  DOI:10.1002/anie.201200596  PMID:22505324  PMCID:PMC3517101
  • Xu, R., McBride, R., Nycholat, C. M., Paulson, J. C., Wilson, I. A. Structural characterization of the hemagglutinin receptor specificity from the 2009 h1n1 influenza pandemic Journal of Virology  2012 86:982-990  DOI:10.1128/jvi.06322-11  PMID:22072785  PMCID:PMC3255799
  • Zeng, Y., Rademacher, C., Nycholat, C. M., Futakawa, S., Lemme, K., Ernst, B., Paulson, J. C. High affinity sialoside ligands of myelin associated glycoprotein Bioorganic & Medicinal Chemistry Letters  2011 21:5045-5049  DOI:10.1016/j.bmcl.2011.04.068  PMID:21561770  PMCID:PMC3156379