Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form
As of April 1st VIVO Scientific Profiles will no longer updated for faculty, and the link to VIVO will be removed from the library website. Faculty profile pages will continue to be updated via Interfolio. VIVO will continue being used behind the scenes to update graduate student profiles. Please contact helplib@scripps.edu if you have questions.
How to download citations from VIVO | Alternative profile options

Induction of DNA-antibodies by d-penicillamine

Academic Article
uri icon
  • Overview
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

authors

  • Webb, J.
  • Pollard, Kenneth Michael

publication date

  • 1985

journal

  • Clinical and Experimental Rheumatology  Journal

abstract

  • As no critical evaluation of native-DNA antibodies due to d-penicillamine (dP) has been made, we have examined this using highly purified DNA fractions obtained by benzoylated-naphthoylated-DEAE-cellulose chromatography. The nDNA, dsDNA, and ds/ss DNA binding was determined in 10 normals, 24 rheumatoid arthritis (RA) patients never on dP, 17 RA patients on dP and in serial sera from 15 of the latter before, during, and after cessation of dP. The results indicate that dP does induce both dsDNA and ssDNA antibodies which persist for many months after its cessation.

subject areas

  • Antibodies, Antinuclear
  • Arthritis, Rheumatoid
  • DNA
  • DNA, Single-Stranded
  • Female
  • Humans
  • Male
  • Middle Aged
  • Penicillamine
  • Time Factors
scroll to property group menus

Identity

International Standard Serial Number (ISSN)

  • 0392-856X

PubMed ID

  • 3876900
scroll to property group menus

Additional Document Info

start page

  • 213

end page

  • 219

volume

  • 3

issue

  • 3

©2022 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support