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Synthesis and biological evaluation of 2 ',4 '- and 3 ',4 '-bridged nucleoside analogues

Academic Article
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Overview

related to degree

  • Ellery, Shelby, Ph.D. in Chemistry, Scripps Research 2006 - 2011

authors

  • Nicolaou, K.C.
  • Ellery, Shelby
  • Rivas, F.
  • Saye, K.
  • Rogers, E.
  • Workinger, T. J.
  • Schallenberger, M.
  • Tawatao, R.
  • Montero, A.
  • Hessell, A.
  • Romesberg, Floyd
  • Carson, D.
  • Burton, Dennis

publication date

  • September 2011

journal

  • Bioorganic & Medicinal Chemistry  Journal

subject areas

  • Anti-Bacterial Agents
  • Antineoplastic Agents
  • Antiviral Agents
  • Cell Line, Tumor
  • Cell Proliferation
  • Dose-Response Relationship, Drug
  • Drug Screening Assays, Antitumor
  • Escherichia coli
  • HEK293 Cells
  • HIV-1
  • Humans
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Nucleosides
  • Staphylococcus aureus
  • Stereoisomerism
  • Structure-Activity Relationship
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Research

keywords

  • Antiviral
  • Cytotoxic
  • Nucleosides
  • Synthesis
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Identity

PubMed Central ID

  • PMC3348725

International Standard Serial Number (ISSN)

  • 0968-0896

Digital Object Identifier (DOI)

  • 10.1016/j.bmc.2011.07.022

PubMed ID

  • 21840722
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Additional Document Info

start page

  • 5648

end page

  • 5669

volume

  • 19

issue

  • 18

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