Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form

A synthetic peptide induces a new anti-dextran idiotype

Academic Article
uri icon
  • Overview
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

authors

  • Seiden, M. V.
  • Clevinger, B.
  • Srouji, T.
  • Davie, J. M.
  • McMillan, S.
  • Lerner, Richard

publication date

  • 1984

journal

  • Annales d'Immunologie  Journal

abstract

  • We have synthesized the JH1 peptide and coupled it to keyhole limpet haemocyanin for use as an immunogen. A serum from an animal hyperimmunized with this immunogen demonstrated binding to both peptide and native immunoglobulin. Furthermore, this serum seems to define an idiotypic determinant nearly unique to alpha (1 ---- 3) dextran-binding immunoglobulins. Synthetic peptide immunogens may be a useful tool in probing the molecular basis of idiotypy.

subject areas

  • Amino Acid Sequence
  • Animals
  • Dextrans
  • Epitopes
  • Immunoglobulin Idiotypes
  • Immunoglobulin Joining Region
  • Immunoglobulin Variable Region
  • Mice
  • Rabbits
scroll to property group menus

Identity

International Standard Serial Number (ISSN)

  • 0300-4910

Digital Object Identifier (DOI)

  • 10.1016/s0769-2625(84)80015-x

PubMed ID

  • 6201130
scroll to property group menus

Additional Document Info

start page

  • 77

end page

  • 82

volume

  • 135C

issue

  • 1

©2021 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support