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Automation of x-ray crystallography

Academic Article
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Overview

authors

  • Abola, E.
  • Kuhn, Peter
  • Earnest, T.
  • Stevens, Raymond

publication date

  • 2000

journal

  • Nature Structural Biology  Journal

abstract

  • Structure-based biological discovery is entering a new era with the development of industrialized macromolecular structure determination pipelines. Intense, highly focused X-rays from integrated synchrotron radiation beam lines combined with significant advances in protein expression, purification, and micro-crystallization automation allow for the full streamlining of the traditionally tedious and time consuming process of determining the three dimensional structures of macromolecules.

subject areas

  • Automation
  • Crystallization
  • Crystallography, X-Ray
  • Protein Conformation
  • Proteins
  • Specimen Handling
  • Synchrotrons
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Identity

International Standard Serial Number (ISSN)

  • 1072-8368

Digital Object Identifier (DOI)

  • 10.1038/80754

PubMed ID

  • 11104004
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Additional Document Info

start page

  • 973

end page

  • 977

volume

  • 7

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