recent publications
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academic article
- Chen, M., Handa, M., Roush, W. R. Enantioselective synthesis of 2-methyl-1,2-syn- and 2-methyl-1,2-anti-3-butenediols via allene hydroboration-aldehyde allylboration reaction sequences Journal of the American Chemical Society 2009 131:14602-14603 DOI:10.1021/ja904599h PMID:19778012 PMCID:PMC2762002
- Handa, M., Scheidt, K. A., Bossart, M., Zheng, N., Roush, W. R. Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment Journal of Organic Chemistry 2008 73:1031-1035 DOI:10.1021/jo702250z PMID:18163645
- Handa, M., Smith, W. J., Roush, W. R. Studies on the synthesis of apoptolidin A. 2. Synthesis of the disaccharide unit Journal of Organic Chemistry 2008 73:1036-1039 DOI:10.1021/jo7022526 PMID:18163646
- Goto, S., Tamura, N., Li, M., Handa, M., Ikeda, Y., Handa, S., Ruggeri, Z. M. Different effects of various anti-GPIIb-IIIa agents on shear-induced platelet activation and expression of procoagulant activity Journal of Thrombosis and Haemostasis 2003 1:2022-2030 DOI:10.1046/j.1538-7836.2003.00349.x PMID:12941046
- Ikeda, Y., Handa, M., Kamata, T., Kawano, K., Kawai, Y., Watanabe, K., Kawakami, K., Sakai, K., Fukuyama, M., Itagaki, I., Yoshioka, A., Ruggeri, Z. M. Transmembrane calcium influx associated with von Willebrand factor binding to GP Ib in the initiation of shear-induced platelet aggregation Thrombosis and Haemostasis 1993 69:496-502 PMID:8391728
- Ikeda, Y., Handa, M., Kawano, K., Kamata, T., Murata, M., Araki, Y., Anbo, H., Kawai, Y., Watanabe, K., Itagaki, I., Sakai, K., Ruggeri, Z. M. The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress Journal of Clinical Investigation 1991 87:1234-1240 DOI:10.1172/jci115124 PMID:2010539 PMCID:PMC295144
- Titani, K., Takio, K., Handa, M., Ruggeri, Z. M. Amino acid sequence of the von Willebrand factor-binding domain of platelet membrane glycoprotein Ib Proceedings of the National Academy of Sciences of the United States of America 1987 84:5610-5614 DOI:10.1073/pnas.84.16.5610 PMID:3497398 PMCID:PMC298912
- Handa, M., Titani, K., Holland, L. Z., Roberts, J. R., Ruggeri, Z. M. The von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Characterization by monoclonal antibodies and partial amino acid sequence analysis of proteolytic fragments Journal of Biological Chemistry 1986 261:2579-2585 PMID:2943738
- Handa, M., Watanabe, K., Zimmerman, T. S., Ruggeri, Z. M. Structure-function relationships of platelet glycoprotein Ib as a receptor for von Willebrand factor Acta Haematologica Japonica 1986 49:1577-1582 PMID:2436428
- Takahashi, H., Handa, M., Watanabe, K., Ando, Y., Nagayama, R., Hattori, A., Shibata, A., Federici, A. B., Ruggeri, Z. M., Zimmerman, T. S. Further characterization of platelet-type von Willebrand's disease in Japan Blood 1984 64:1254-1262 PMID:6333901