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articles

  • The orphan receptor GPR139 signals via G(q/11)to oppose opioid effects.  295:10822-10830. 2020
  • Correction of Niemann-Pick type C1 trafficking and activity with the histone deacetylase inhibitor valproic acid.  295:8017-8035. 2020
  • AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.  295:5891-5905. 2020
  • Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.  295:5995-6006. 2020
  • Cell adhesion in cancer: Beyond the migration of single cells.  295:2495-2505. 2020
  • A distinct talin2 structure directs isoform specificity in cell adhesion.  295:12885-12899. 2020
  • FOXO1 transcription factor regulates chondrogenic differentiation through transforming growth factor β1 signaling.  294:17555-17569. 2019
  • Leveraging a large microbial strain collection for natural product discovery.  294:16567-16576. 2019
  • Molecular interaction site on procoagulant myosin for factor Xa?dependent prothrombin activation.  294:15176-15181. 2019
  • Setting the dynein motor in motion: New insights from electron tomography.  294:13202-13217. 2019
  • The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity.  294:13366-13377. 2019
  • The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium channel in the prelimbic cortex.  294:13145-13157. 2019
  • Discovery of an intrasubunit nicotinic acetylcholine receptor-binding site for the positive allosteric modulator Br-PBTC.  294:12132-12145. 2019
  • Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals.  294:10698-10707. 2019
  • Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription.  294:8592-8605. 2019
  • A complex containing the O-GlcNAc transferase OGT-1 and the ubiquitin ligase EEL-1 regulates GABA neuron function.  294:6843-6856. 2019
  • Identification and characterization of NanH2 and NanH3, enzymes responsible for sialidase activity in the vaginal bacterium Gardnerella vaginalis.  294:5230-5245. 2019
  • Neurodegenerative Charcot-Marie-Tooth disease as a case study to decipher novel functions of aminoacyl-tRNA synthetases.  294:5321-5339. 2019
  • Stabilization of the V2 loop improves the presentation of V2 loop-associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers.  294:5616-5631. 2019
  • Challenges and opportunities in cryo-EM single-particle analysis.  294:5181-5197. 2019
  • DNA polymerase θ (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse.  294:3909-3919. 2019
  • Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures.  294:1846-1859. 2019
  • Milestones in transcription and chromatin published in the Journal of Biological Chemistry.  294:1652-1660. 2019
  • Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.  294:953-967. 2019
  • The properties of Msh2-Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair.  293:18055-18070. 2018
  • Dissecting MMP P-10 and P-11 subsite sequence preferences, utilizing a positional scanning, combinatorial triple-helical peptide library.  293:16661-16676. 2018
  • Molecular interactions connecting the function of the serine-arginine-rich protein SRSF1 to protein phosphatase 1.  293:16751-16760. 2018
  • Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).  293:16851-16861. 2018
  • Phosphoserine acidic cluster motifs bind distinct basic regions on the mu subunits of clathrin adaptor protein complexes.  293:15678-15690. 2018
  • Introduction to the Thematic Minireview Series: Chromatin and transcription.  293:13775-13777. 2018
  • PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.  293:13897-13909. 2018
  • Correcting the F508del-CFTR variant by modulating eukaryotic translation initiation factor 3-mediated translation initiation.  293:13477-13495. 2018
  • Silencing of the Hsp70-specific nucleotide-exchange factor BAG3 corrects the F508del-CFTR variant by restoring autophagy.  293:13682-13695. 2018
  • Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes.  293:12259-12270. 2018
  • The crystal structure of the Helicobacter pylori LlaJI.R1 N-terminal domain provides a model for site-specific DNA binding.  293:11758-11771. 2018
  • Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1.  293:11433-11446. 2018
  • Structural basis for disassembly of katanin heterododecamers.  293:10590-10605. 2018
  • Crystal structure of the human 4-1BB/4-1BBL complex.  293:9880-9891. 2018
  • Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling.  293:9388-9398. 2018
  • Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.  293:8439-8448. 2018
  • Making useful gadgets with miniaturized G proteins.  293:7474-7475. 2018
  • The serine protease HtrA1 contributes to the formation of an extracellular 25-kDa apolipoprotein E fragment that stimulates neuritogenesis.  293:4071-4084. 2018
  • A cationic, C-terminal patch and structural rearrangements in Ebola virus matrix VP40 protein control its interactions with phosphatidylserine.  293:3335-3349. 2018
  • A global view of structure-function relationships in the tautomerase superfamily.  293:2342-2357. 2018
  • Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers.  293:1688-1701. 2018
  • Translation efficiency is maintained at elevated temperature in Escherichia coli.  293:777-793. 2018
  • Time-course, negative-stain electron microscopy-based analysis for investigating protein-protein interactions at the single-molecule level.  292:19400-19410. 2017
  • Early emergence of negative regulation of the tyrosine kinase Src by the C-terminal Src kinase.  292:18518-18529. 2017
  • Chimeric rabbit/human Fab antibodies against the hepatitis Be-antigen and their potential applications in assays, characterization, and therapy.  292:16760-16772. 2017
  • An in vitro tag-and-modify protein sample generation method for single-molecule fluorescence resonance energy transfer.  292:15636-15648. 2017
  • Characterization of a stable HIV-1B/C recombinant, soluble, and trimeric envelope glycoprotein (Env) highly resistant to CD4-induced conformational changes.  292:15849-15858. 2017
  • Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development.  292:15121-15132. 2017
  • LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.  292:14989-15001. 2017
  • Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing.  292:12653-12666. 2017
  • Structural studies unravel the active conformation of apo RORγt nuclear receptor and a common inverse agonism of two diverse classes of RORγt inhibitors.  292:11618-11630. 2017
  • The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans.  292:11861-11872. 2017
  • Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition.  292:11230-11242. 2017
  • Human milk oligosaccharides inhibit growth of group B Streptococcus.  292:11243-11249. 2017
  • Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.  292:10328-10346. 2017
  • Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.  292:10398-10413. 2017
  • Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo.  292:8616-8629. 2017
  • An antidote approach to reduce risk and broaden utility of antibody-based therapeutics.  292:8498-8506. 2017
  • Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoprotein.  292:8236-8243. 2017
  • Negative stain single-particle EM of the maltose transporter in nanodiscs reveals asymmetric closure of MalK2 and catalytic roles of ATP, MalE, and maltose.  292:5457-5464. 2017
  • The crystal structure of cytochrome P450 4B1 (CYP4B1) monooxygenase complexed with octane discloses several structural adaptations for ω-hydroxylation.  292:5610-5621. 2017
  • Targeted Fcγ receptor (FcγR)-mediated clearance by a biparatopic bispecific antibody.  292:4361-4370. 2017
  • Inhibition of Ubc13-mediated ubiquitination by GPS2 regulates multiple stages of B cell development.  292:2754-2772. 2017
  • Defining minimal binding regions in regulator of presynaptic morphology 1 (RPM-1) using Caenorhabditis elegans neurons reveals differential signaling complexes.  292:2519-2530. 2017
  • The major protein arginine methyltransferase in Trypanosoma brucei functions as an enzyme-prozyme complex.  292:2089-2100. 2017
  • Bacterial polysaccharide specificity of the pattern recognition receptor langerin is highly species- dependent.  292:862-871. 2017
  • Secreted glioblastoma nanovesicles contain intracellular signaling proteins and active Ras incorporated in a farnesylation-dependent manner.  292:611-628. 2017
  • Evolution of negative cooperativity in glutathione transferase enabled preservation of enzyme function.  291:26739-26749. 2016
  • Role for the MED21-MED7 hinge in assembly of the mediator-RNA polymerase II holoenzyme.  291:26886-26898. 2016
  • Bacterial energy sensor Aer modulates the activity of the chemotaxis kinase CheA based on the redox state of the flavin cofactor.  291:25809-25814. 2016
  • Identification of neutrophil exocytosis inhibitors (Nexinhibs), small molecule inhibitors of neutrophil exocytosis and inflammation: druggability of the small GTPase Rab27a.  291:25965-25982. 2016
  • Crystal structures of the nuclear receptor, liver receptor homolog 1, bound to synthetic agonists.  291:25281-25291. 2016
  • URI regulates KAP1 phosphorylation and transcriptional repression via PP2A phosphatase in prostate cancer cells.  291:25516-25528. 2016
  • Small molecule inhibition of the ubiquitin-specific protease USP2 accelerates cyclin D1 degradation and leads to cell cycle arrest in colorectal cancer and mantle cell Lymphoma Models.  291:24628-24640. 2016
  • A new class of allosteric HIV-1 integrase inhibitors identified by crystallographic fragment screening of the catalytic core domain.  291:23569-23577. 2016
  • Unorthodox acetylcholine binding sites formed by α5 and β3 accessory subunits in α4β2* nicotinic acetylcholine receptors.  291:23452-23463. 2016
  • Chemically programmed bispecific antibodies in diabody format.  291:19661-19673. 2016
  • Protein arginine methyltransferase product specificity is mediated by distinct active-site architectures.  291:18299-18308. 2016
  • 20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: Normalization of blood pressure by sodium restriction, hydrochlorothiazide, or blockade of the type 1 angiotensin II receptor.  291:16904-16919. 2016
  • Natural product anacardic acid from cashew nut shells stimulates neutrophil extracellular trap production and bactericidal activity.  291:13964-13973. 2016
  • Regulatory T cell modulation by CBP/EP300 bromodomain inhibition.  291:13014-13027. 2016
  • Structural determinants of binding the seven-transmembrane domain of the glucagon-like peptide-1 receptor (GLP-1R).  291:12991-13004. 2016
  • Formation of a chloride-conducting state in the maltose ATP-binding cassette (ABC) transporter.  291:12119-12125. 2016
  • Poly(ADP-ribose) polymerase 1 represses liver X receptor-mediated ABCA1 expression and cholesterol efflux in macrophages.  291:11172-11184. 2016
  • The methionine transamination pathway controls hepatic glucose metabolism through regulation of the GCN5 acetyltransferase and the PGC-1α transcriptional coactivator.  291:10635-10645. 2016
  • Crystal structure and activity studies of the C11 cysteine peptidase from parabacteroides merdae in the human gut microbiome.  291:9482-9491. 2016
  • Regulator of G protein signaling 7 (RGS7) can exist in a homo-oligomeric form that is regulated by Gαo and R7-binding protein.  291:9133-9147. 2016
  • Targeting stereotyped B cell receptors from chronic lymphocytic leukemia patients with synthetic antigen surrogates.  291:7558-7570. 2016
  • Association with the plasma membrane is sufficient for potentiating catalytic activity of regulators of G protein signaling (RGS) proteins of the R7 subfamily.  291:7195-7204. 2016
  • Role of intrinsic protein disorder in the function and interactions of the transcriptional coactivators CREB-binding protein (CBP) and p300.  291:6714-6722. 2016
  • Identifying a small molecule blocking antigen presentation in autoimmune thyroiditis.  291:4079-4090. 2016
  • Munc13-4 Is a Rab11-binding protein that regulates Rab11-positive vesicle trafficking and docking at the plasma membrane.  291:3423-3438. 2016
  • Mechanisms and functions of vinculin interactions with phospholipids at cell adhesion sites.  291:2548-2555. 2016
  • Increasing the receptor tyrosine kinase EphB2 prevents amyloid-β-induced depletion of cell surface glutamate receptors by a mechanism that requires the PDZ-binding motif of EphB2 and neuronal activity.  291:1719-1734. 2016
  • Branched fatty acid esters of hdroxy fatty acids (FAHFAs) protect against colitis by regulating gut innate and adaptive immune responses.  291:22207-22217. 2016
  • Unmasking of CD22 co-receptor on germinal center B-cells occurs by alternative mechanisms in mouse and man.  290:30066-30077. 2015
  • Assembly of multi-tRNA synthetase complex via heterotetrameric glutathione transferase-homology domains.  290:29313-29328. 2015
  • A novel α2/α4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors acting from the C-tail of an α subunit.  290:28834-28846. 2015
  • The natural product N-palmitoyl-l-leucine selectively inhibits late assembly of human spliceosomes.  290:27524-27531. 2015
  • The triggering receptor expressed on myeloid cells 2 binds apolipoprotein E.  290:26033-26042. 2015
  • Sequential action of MalE and maltose allows coupling ATP hydrolysis to translocation in the MalFGK(2) transporter.  290:25452-25460. 2015
  • Pli1(PIAS1) SUMO ligase protected by the nuclear pore-associated SUMO protease Ulp1(SENP1/2).  290:22678-22685. 2015
  • Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes.  290:22919-22930. 2015
  • The N-terminal domain of Escherichia coli assimilatory NADPH-Sulfite reductase hemoprotein is an oligomerization domain that mediates holoenzyme assembly.  290:19319-19333. 2015
  • Thematic minireview series: The state of the cytoskeleton in 2015.  290:17133-17136. 2015
  • The influence of nitric oxide on soluble guanylate cyclase regulation by nucleotides: Role of the pseudosymmetric site.  290:15570-15580. 2015
  • An accessory agonist binding site promotes activation of α4β2* nicotinic acetylcholine receptors.  290:13907-13918. 2015
  • Orphan receptor GPR158 is an allosteric modulator of RGS7 catalytic activity with an essential role in dictating its expression and localization in the brain.  290:13622-13639. 2015
  • Tyrosine kinase 2-mediated signal transduction in T lymphocytes is blocked by pharmacological stabilization of Its pseudokinase domain.  290:11061-11074. 2015
  • Integration of G protein a (Ga) signaling by the regulator of G protein signaling 14 (RGS14).  290:9037-9049. 2015
  • RNA toxicity and missplicing in the common eye disease fuchs endothelial corneal dystrophy.  290:5979-5990. 2015
  • Contributions of ionic interactions and protein dynamics to cytochrome P450 2D6 (CYP2D6) substrate and inhibitor binding.  290:5092-5104. 2015
  • The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells.  290:1623-1638. 2015
  • Systemic blockade of sialylation in mice with a global inhibitor of sialyltransferases.  289:35149-35158. 2014
  • Identification of a peptide inhibitor of the RPM-1 · FSN-1 ubiquitin ligase complex.  289:34654-34666. 2014
  • Novel mechanism of hemin capture by Hbp2, the hemoglobin-binding hemophore from Listeria monocytogenes.  289:34886-34899. 2014
  • Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells.  289:33741-33753. 2014
  • Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.  289:33557-33567. 2014
  • Systematic analysis of bacterial effector-postsynaptic density 95/disc large/zonula occludens-1 (PDZ) domain interactions demonstrates Shigella OspE protein promotes protein kinase C activation via PDLIM proteins.  289:30101-30113. 2014
  • Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication.  289:28910-28923. 2014
  • A critical role of the C-terminal segment for allosteric inhibitor-induced aberrant multimerization of HIV-1 integrase.  289:26430-26440. 2014
  • Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity.  289:25737-25749. 2014
  • Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.  289:25750-25763. 2014
  • Reelin induces Erk1/2 signaling in cortical neurons through a non-canonical pathway.  289:20307-20317. 2014
  • Structure of REV-ERB beta ligand-binding domain bound to a porphyrin antagonist.  289:20054-20066. 2014
  • Casein kinase 1 delta-dependent Wee1 protein degradation.  289:18893-18903. 2014
  • Secreted histidyl-tRNA synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis.  289:19269-19275. 2014
  • Specificity and catalytic mechanism in family 5 uracil DNA glycosylase.  289:18413-18426. 2014
  • Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor beta/delta (FABP5-PPAR beta/delta) signaling pathway.  289:14941-14954. 2014
  • Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1.  289:13717-13725. 2014
  • Fragments of bacterial endoglycosidase s and immunoglobulin g reveal subdomains of each that contribute to deglycosylation.  289:13876-13889. 2014
  • Differential actin-regulatory activities of Tropomodulin1 and Tropomodulin3 with diverse tropomyosin and actin isoforms.  289:11616-11629. 2014
  • Induction of retinal progenitors and neurons from mammalian Müller glia under defined conditions.  289:11945-11951. 2014
  • A human short open reading frame (sORF)-encoded polypeptide that stimulates DNA end joining.  289:10950-10957. 2014
  • Adenovirus composition, proteolysis, and disassembly studied by in-depth qualitative and quantitative proteomics.  289:11421-11430. 2014
  • Nucleotide-free MalK drives the transition of the maltose transporter to the inward-facing conformation.  289:9844-9851. 2014
  • Structural insights into neonatal Fc receptor-based recycling mechanisms.  289:7812-7824. 2014
  • Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity.  289:6551-6564. 2014
  • Matricellular protein Cyr61 bridges lysophosphatidic acid and integrin pathways leading to cell migration.  289:5774-5783. 2014
  • Rheb GTPase regulates beta-secretase levels and amyloid beta generation.  289:5799-5808. 2014
  • Genomic instability in pluripotent stem cells: implications for clinical applications.  289:4578-4584. 2014
  • Introduction to thematic minireview series: Development of human therapeutics based on induced pluripotent stem cell (iPSC) technology.  289:4553-4554. 2014
  • Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy.  289:3547-3554. 2014
  • RGS6, but not RGS4, is the dominant regulator of G protein signaling (RGS) modulator of the parasympathetic regulation of mouse heart rate.  289:2440-2449. 2014
  • Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation.  289:1491-1504. 2014
  • Defining the communication between agonist and coactivator binding in the retinoid X receptor alpha ligand binding domain.  289:814-826. 2014
  • Development of functionally selective, small molecule agonists at kappa opioid receptors.  288:36703-36716. 2013
  • Chemotype-selective modes of action of κ-opioid receptor agonists.  288:34470-34483. 2013
  • Substrate cleavage profiling suggests a distinct function of Bacteroides fragilis metalloproteinases (fragilysin and metalloproteinase II) at the microbiome-inflammation-cancer interface.  288:34956-34967. 2013
  • Interferon-induced transmembrane protein 3 is a type II transmembrane protein.  288:32184-32193. 2013
  • Regulation of the structurally dynamic N-terminal domain of progesterone receptor by protein-induced folding.  288:30285-30299. 2013
  • Regulated capture by exosomes of mRNAs for cytoplasmic tRNA synthetases.  288:29223-29228. 2013
  • Sphingosine 1-phosphate receptors are essential mediators of eyelid closure during embryonic development.  288:29882-29889. 2013
  • FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas.  288:29105-29114. 2013
  • Characterization of a serine hydrolase targeted by acyl-protein thioesterase inhibitors in Toxoplasma gondii.  288:27002-27018. 2013
  • Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability.  288:26926-26943. 2013
  • The redox biochemistry of protein sulfenylation and sulfinylation.  288:26480-26488. 2013
  • Dual role of BAR domain-containing proteins in regulating vesicle release catalyzed by the GTPase, dynamin-2.  288:25119-25128. 2013
  • Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells.  288:25129-25142. 2013
  • Peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells.  288:25207-25218. 2013
  • Energy transducing roles of antiporter-like subunits in Escherichia coli NDH-1 with main focus on subunit NuoN (ND2).  288:24705-24716. 2013
  • Phosphatidylglycerol directs binding and inhibitory action of EIIAGlc protein on the maltose transporter.  288:23666-23674. 2013
  • Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at kappa-opioid receptors in striatal neurons.  288:22387-22398. 2013
  • Solution NMR analyses of the C-type carbohydrate recognition domain of DC-SIGNR protein reveal different binding modes for HIV-derived oligosaccharides and smaller glycan fragments.  288:22745-22757. 2013
  • Characterization of the human sigma-1 receptor chaperone domain structure and binding immunoglobulin protein (BiP) interactions.  288:21448-21457. 2013
  • Divergent sequence tunes ligand sensitivity in phospholipid-regulated hormone receptors.  288:20702-20712. 2013
  • Direct expression and validation of phage-selected peptide variants in mammalian cells.  288:18803-18810. 2013
  • Enzymatic detoxication, conformational selection, and the role of molten globule active sites.  288:18599-18611. 2013
  • Engineering A-kinase anchoring protein (AKAP)-selective regulatory subunits of protein kinase A (PKA) through structure-based phage selection.  288:17111-17121. 2013
  • Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation.  288:17360-17371. 2013
  • Structure and function of the DUF2233 domain in bacteria and in the human mannose 6-phosphate uncovering enzyme.  288:16789-16799. 2013
  • Semiquinone and cluster N6 signals in His-tagged proton-translocating NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli.  288:14310-14319. 2013
  • Structure and activity of the flagellar rotor protein FliY: a member of the CheC phosphatase family.  288:13493-13502. 2013
  • Degradation, foraging, and depletion of mucus sialoglycans by the vagina-adapted Actinobacterium Gardnerella vaginalis.  288:12067-12079. 2013
  • γ-Secretase modulator (GSM) photoaffinity probes reveal distinct allosteric binding sites on presenilin.  288:9710-9720. 2013
  • Variable electron transfer pathways in an amphibian cryptochrome: Tryptophan versus tyrosine-based radical pairs.  288:9249-9260. 2013
  • Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.  288:8445-8455. 2013
  • Binding of a cyano- and fluoro-containing drug bicalutamide to cytochrome p450 46a1 unusual features and spectral response.  288:4613-4624. 2013
  • Identification of the low density lipoprotein (ldl) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris.  288:4538-4548. 2013
  • RegB kinase activity is repressed by oxidative formation of cysteine sulfenic acid.  288:4755-4762. 2013
  • Inhibition of JNK mitochondrial localization and signaling is protective against ischemia/reperfusion injury in rats.  288:4000-4011. 2013
  • ATP alone triggers the outward facing conformation of the maltose ATP-binding cassette transporter.  288:3439-3448. 2013
  • Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage.  288:2941-2950. 2013
  • Evolution of broad spectrum β-lactam resistance in an engineered metallo-β-lactamase.  288:2314-2324. 2013
  • Blocking c-jun n-terminal kinase (jnk) translocation to the mitochondria prevents 6-hydroxydopamine-induced toxicity in vitro and in vivo.  288:1079-1087. 2013
  • [Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes.  288:35358-35371. 2013
  • F-box and leucine-rich repeat protein 5 (FBXL5) is required for maintenance of cellular and systemic iron homeostasis.  288:552-560. 2013
  • Integration and long distance axonal regeneration in the central nervous system from transplanted primitive neural stem cells.  288:164-168. 2013
  • Automethylation of protein arginine methyltransferase 8 (PRMT8) regulates activity by impeding S-adenosylmethionine sensitivity.  288:27872-27880. 2013
  • Structural diversity of eukaryotic membrane cytochrome P450s.  288:17082-17090. 2013
  • Structural characterization of human cytochrome P450 2C19: active site differences between P450s 2C8, 2C9, and 2C19.  287:44581-44591. 2012
  • Localization and substrate selectivity of sea urchin multidrug (MDR) efflux transporters.  287:43876-43883. 2012
  • The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination.  287:43984-43994. 2012
  • Heme-assisted S-nitrosation desensitizes ferric soluble guanylate cyclase to nitric oxide.  287:43053-43062. 2012
  • Engineered disulfide-forming amino acid substitutions interfere with a conformational change in the mismatch recognition complex Msh2-Msh6 required for mismatch repair.  287:41232-41244. 2012
  • Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway.  287:38656-38664. 2012
  • Histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of alpha 1-antitrypsin deficiency.  287:38265-78. 2012
  • Amyloid fibrils trigger the release of neutrophil extracellular traps (NETs), causing fibril fragmentation by NET-associated elastase.  287:37206-37218. 2012
  • Fibrils colocalize caspase-3 with procaspase-3 to foster maturation.  287:33781-33795. 2012
  • Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.  287:31747-31756. 2012
  • Correlation between NS5A dimerization and hepatitis C virus replication.  287:30861-30873. 2012
  • Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions.  287:29610-29619. 2012
  • Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-beta-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes.  287:30024-30034. 2012
  • Role of mismatch repair enzymes in GAA.TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells.  287:29861-29872. 2012
  • Chemically programmed bispecific antibodies that recruit and activate T cells.  287:28206-28214. 2012
  • Metabolism of vertebrate amino sugars with N-glycolyl groups: intracellular beta-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc, and the biochemical and structural rationale for the substrate tolerance of beta-O-linked beta-N-acetylglucosaminidase.  287:28882-28897. 2012
  • Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.  287:28215-28226. 2012
  • Protein dynamics and the diversity of an antibody response.  287:27139-27147. 2012
  • Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins.  287:24534-24543. 2012
  • Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers.  287:24239-24254. 2012
  • Ultrahigh and high resolution structures and mutational analysis of monomeric streptococcus pyogenes speb reveal a functional role for the glycine-rich c-terminal loop.  287:24412-24426. 2012
  • Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms.  287:23710-23717. 2012
  • FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR) folding and stability.  287:21914-21925. 2012
  • L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity.  287:22206-22215. 2012
  • Multiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair.  287:21846-21855. 2012
  • Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis.  287:21599-21614. 2012
  • Structural tuning of the fluorescent protein iLOV for improved photostability.  287:22295-22304. 2012
  • CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks.  287:21471-21480. 2012
  • New class of HIV-1 integrase (IN) inhibitors with a dual mode of action.  287:21189-21203. 2012
  • Uncovering of a short internal peptide activates a tRNA synthetase procytokine.  287:20504-20508. 2012
  • Identification of a conserved interface between PUF and CPEB proteins.  287:18854-18862. 2012
  • The Cytoskeletal Protein α-Catenin unfurls upon binding to vinculin.  287:18492-18499. 2012
  • Electron transfer in subunit nuoi (tyky) of escherichia coli nadh:Quinone oxidoreductase (ndh-1).  287:17363-17373. 2012
  • Targeted deletion of LPA5 identifies novel roles for lysophosphatidic acid signaling in development of neuropathic pain.  287:17608-17617. 2012
  • Insights into mechanism of glucokinase activation: observation of multiple distinct protein conformations.  287:13598-13610. 2012
  • Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule.  287:13611-13619. 2012
  • Enzyme kinetics and interaction studies for human jnk1 beta 1 and substrates activating transcription factor 2 (atf2) and c-jun n-terminal kinase (c-jun).  287:13291-13302. 2012
  • T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.  287:13324-13335. 2012
  • Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants.  287:12060-12069. 2012
  • Crystal structure of human cytochrome p450 2d6 with prinomastat bound.  287:10834-10843. 2012
  • Human protein n-terminal acetyltransferase hnaa50p (hnat5/hsan) follows ordered sequential catalytic mechanism combined kinetic and NMR study.  287:10081-10088. 2012
  • Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics.  287:9742-9752. 2012
  • Constitutive nadph oxidase 4 activity resides in the composition of the b-loop and the penultimate c terminus.  287:8737-8745. 2012
  • tRNA-controlled nuclear import of a human tRNA synthetase.  287:9330-9334. 2012
  • Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis.  287:7990-8000. 2012
  • Structural insights into charge pair interactions in triple helical collagen-like proteins.  287:8039-8047. 2012
  • Structural and molecular characterization of iron-sensing hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5).  287:7357-7365. 2012
  • Five decades with glutathione and the GSTome.  287:6072-6083. 2012
  • Biochemically defined hiv-1 envelope glycoprotein variant immunogens display differential binding and neutralizing specificities to the cd4-binding site.  287:5673-5686. 2012
  • Engineering Upper Hinge Improves Stability and Effector Function of a Human IgG1.  287:5891-5897. 2012
  • Kinetic mechanism of protein arginine methyltransferase 6 (prmt6).  287:6062-6071. 2012
  • Histone H3 lysine 14 acetylation is required for activation of a DNA damage checkpoint in fission yeast.  287:4386-4393. 2012
  • Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.  287:2531-2543. 2012
  • Hydrolysis of secreted sialoglycoprotein immunoglobulin A (IgA) in ex vivo and biochemical models of bacterial vaginosis.  287:2079-2089. 2012
  • Dhhc5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells.  287:523-530. 2012
  • Identification and mechanism of 10-carbon fatty acid as modulating ligand of peroxisome proliferator-activated receptors.  287:183-195. 2012
  • Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli.  287:123-133. 2012
  • Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases.  287:11798-11809. 2012
  • In vitro and in vivo anticancer activity of a synthetic glycolipid as Toll-like receptor 4 (TLR4) activator.  286:43782-43792. 2011
  • Ultrahigh resolution and full-length pilin structures with insights for filament assembly, pathogenic functions, and vaccine potential.  286:44254-44265. 2011
  • Expression patterns and function of chromatin protein HMGB2 during mesenchymal stem cell differentiation.  286:41489-41498. 2011
  • Abrogation of complex glycosylation by swainsonine results in strain- and cell-specific inhibition of prion replication.  286:40962-40973. 2011
  • Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis.  286:40771-40781. 2011
  • Identification of a novel Mcl-1 protein binding motif.  286:39829-39835. 2011
  • Translational suppression of atrophic regulators by microRNA-23a integrates resistance to skeletal muscle atrophy.  286:38456-38465. 2011
  • Structural and kinetic analysis of substrate binding to the sialyltransferase Cst-II from Campylobacter jejuni.  286:35922-35932. 2011
  • The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.  286:35096-35103. 2011
  • Rcl1 protein, a novel nuclease for 18 S ribosomal RNA production.  286:34082-34087. 2011
  • Role of net charge on catalytic domain and influence of cell wall binding domain on bactericidal activity, specificity, and host range of phage lysins.  286:34391-34403. 2011
  • Structural contribution of c-terminal segments of nuol (nd5) and nuom (nd4) subunits of complex i from escherichia coli.  286:34007-34014. 2011
  • The novel plasminogen receptor, plasminogen receptor(KT) (Plg-R(KT)), regulates catecholamine release.  286:33125-33133. 2011
  • Improvement of a potential anthrax therapeutic by computational protein design.  286:32586-32592. 2011
  • Xrcc4 protein interactions with xrcc4-like factor (xlf) create an extended grooved scaffold for DNA ligation and double strand break repair.  286:32638-32650. 2011
  • A small molecule that mimics the BB-loop in the Toll Interleukin-1 (IL-1) receptor domain of MyD88 attenuates Staphylococcal enterotoxin B-induced pro-inflammatory cytokine production and toxicity in mice.  286:31385-31396. 2011
  • Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.  286:31731-31741. 2011
  • New family of deamination repair enzymes in uracil-DNA glycosylase superfamily.  286:31282-31287. 2011
  • Neutralizing mutations of carboxylates that bind metal 2 in t5 flap endonuclease result in an enzyme that still requires two metal ions.  286:30878-30887. 2011
  • Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging.  286:29718-29724. 2011
  • Interaction of transducin with uncoordinated 119 protein (UNC119) implications for the model of transducin trafficking in rod photoreceptors.  286:28954-28962. 2011
  • Deciphering the role of histidine 252 in mycobacterial adenosine 5'-phosphosulfate (APS) reductase catalysis.  286:28567-28573. 2011
  • Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities.  286:28435-28443. 2011
  • Novel vinculin binding site of the IpaA invasin of Shigella.  286:23214-23221. 2011
  • Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORγt protein.  286:22707-22710. 2011
  • A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses.  286:22250-22261. 2011
  • Type 5 G protein beta subunit (G beta 5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors.  286:21806-21813. 2011
  • Determination of structural models of the complex between the cytoplasmic domain of erythrocyte band 3 and ankyrin-R repeats 13-24.  286:20746-20757. 2011
  • Di-acidic motifs in the membrane-distal C termini modulate the transport of angiotensin II receptors from the endoplasmic reticulum to the cell surface.  286:20525-20535. 2011
  • Structural characterization and epitope mapping of the glutamic acid/alanine-rich protein from Trypanosoma congolense: defining assembly on the parasite cell surface.  286:20658-20665. 2011
  • New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases.  286:19422-19430. 2011
  • The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism.  286:19758-19767. 2011
  • Matrix metalloproteinase (MMP)-9 induced by Wnt signaling increases the proliferation and migration of embryonic neural stem cells at low O2 levels.  286:17649-17657. 2011
  • The pH dependence of hairpin ribozyme catalysis reflects ionization of an active site adenine.  286:17658-17664. 2011
  • Cys-X scanning for expansion of active-site residues and modulation of catalytic functions in a glutathione transferase.  286:16871-16878. 2011
  • Structural basis for ligand recognition and discrimination of a quorum-quenching antibody.  286:17351-17358. 2011
  • Co2+ selectivity of thermotoga maritima cora and its inability to regulate mg2+ homeostasis present a new class of cora proteins.  286:16525-32. 2011
  • Mitochondrial c-jun n-terminal kinase (jnk) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation.  286:16052-16062. 2011
  • Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors.  286:14983-14990. 2011
  • Liver x receptor-retinoid x receptor (lxr-rxr) heterodimer cistrome reveals coordination of lxr and ap1 signaling in keratinocytes.  286:14554-14563. 2011
  • Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val-251.  286:14057-14064. 2011
  • Crystal structure of the human n-myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.  286. 2011
  • Methylsulfonylnitrobenzoates, a new class of irreversible inhibitors of the interaction of the thyroid hormone receptor and its obligate coactivators that functionally antagonizes thyroid hormone.  286:11895-11908. 2011
  • Dissociating quaternary structure regulates cell-signaling functions of a secreted human tRNA synthetase.  286:11563-11568. 2011
  • The dynamics and mechanism of SUMO chain deconjugation by SUMO-specific proteases.  286:10238-10247. 2011
  • Reaction mechanism of single subunit nadh-ubiquinone oxidoreductase (ndi1) from saccharomyces cerevisiae evidence for a ternary complex mechanism.  286:9287-9297. 2011
  • Structural insights into inhibition of bacillus anthracis sporulation by a novel class of non-heme globin sensor domains.  286:8448-8458. 2011
  • T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component.  286:7535-7547. 2011
  • A specific interaction of small molecule entry inhibitors with the envelope glycoprotein complex of the Junin hemorrhagic fever arenavirus.  286:6192-6200. 2011
  • Atp induces conformational changes in the carboxyl-terminal region of clc-5.  286:6733-6741. 2011
  • Munc13-4 restricts motility of rab27a-expressing vesicles to facilitate lipopolysaccharide-induced priming of exocytosis in neutrophils.  286:5647-5656. 2011
  • Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme cyp11a1.  286:5607-5613. 2011
  • Structural characterization of the complex between alpha-naphthoflavone and human cytochrome P450 1B1.  286:5736-5743. 2011
  • The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors.  286:5756-5767. 2011
  • Roles of Dim2 in ribosome assembly.  286:2578-2586. 2011
  • Spectroscopic studies on the [4Fe-4S] cluster in adenosine 5'-phosphosulfate reductase from Mycobacterium tuberculosis.  286:1216-1226. 2011
  • Platelet factor 4 inhibits thrombomodulin-dependent activation of thrombin-activatable fibrinolysis inhibitor (tafi) by thrombin.  286:502-510. 2011
  • Identification of Escherichia coli mismatch-specific uracil DNA glycosylase as a robust xanthine DNA glycosylase.  285:41483-41490. 2010
  • The v-myc-induced Q83 lipocalin is a siderocalin.  285:41646-41652. 2010
  • A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins.  285:41100-41112. 2010
  • Altered chaperone-like activity of α-crystallins promotes cataractogenesis.  285:41187-41193. 2010
  • Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance.  285:40416-40426. 2010
  • Plasticity of cytochrome P450 2B4 as investigated by hydrogen-deuterium exchange mass spectrometry and X-ray crystallography.  285:38602-38611. 2010
  • Characterization of fdmv as an amide synthetase for fredericamycin a biosynthesis in streptomyces griseus atcc 43944.  285:38853-38860. 2010
  • The membrane subunit nuol(nd5) is involved in the indirect proton pumping mechanism of escherichia coli complex i.  285:39070-39078. 2010
  • Methylation of the retinoblastoma tumor suppressor by SMYD2.  285:37733-37740. 2010
  • Substrates of the Arabidopsis thaliana protein isoaspartyl methyltransferase 1 identified using phage display and biopanning.  285:37281-37292. 2010
  • Characterization of the core mammalian clock component, NPAS2, as a REV-ERB alpha/ROR alpha target gene.  285:35386-35392. 2010
  • Mammalian tropomodulins nucleate actin polymerization via their actin monomer binding and filament pointed end-capping activities.  285:33265-33280. 2010
  • Metabolic depression and increased reactive oxygen species production by isolated mitochondria at moderately lower temperatures.  285:32522-32528. 2010
  • Nitric-oxide synthase forms N-NO-pterin and S-NO-cys: implications for activity, allostery, and regulation.  285:31581-31589. 2010
  • Structural basis of drug binding to cyp46a1, an enzyme that controls cholesterol turnover in the brain.  285:31783-31795. 2010
  • Transportin regulates nuclear import of CD44.  285:30548-30557. 2010
  • Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules.  285:29676-29680. 2010
  • Parkin enhances the expression of cyclin-dependent kinase 6 and negatively regulates the proliferation of breast cancer cells.  285:29231-29238. 2010
  • Structural insights into the catalytic mechanism of bacterial guanosine-diphospho-D-mannose pyrophosphorylase and its regulation by divalent ions.  285:27468-27476. 2010
  • Proteolysis-induced n-terminal ectodomain shedding of the integral membrane glycoprotein cub domain-containing protein 1 (cdcp1) is accompanied by tyrosine phosphorylation of its c-terminal domain and recruitment of src and pkc delta.  285:26162-26173. 2010
  • Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular process.  285:25753-25766. 2010
  • Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity.  285:25699-25707. 2010
  • Protein S-thiolation by Glutathionylspermidine (Gsp): the role of Escherichia coli Gsp synthetASE/amidase in redox regulation.  285:25345-25353. 2010
  • LC3-dependent intracellular membrane tubules induced by gamma-protocadherins A3 and B2: a role for intraluminal interactions.  285:20982-20992. 2010
  • Nucleosome interaction surface of linker histone H1c is distinct from that of H1(0).  285:20891-20896. 2010
  • Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.  285:20428-20432. 2010
  • Engineering of substrate selectivity for tissue factor.Factor viia complex signaling through protease-activated receptor 2.  285:19959-19966. 2010
  • Oxazolomycin biosynthesis in streptomyces albus ja3453 featuring an "acyltransferase-less" type i polyketide synthase that incorporates two distinct extender units.  285:20097-20108. 2010
  • A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target.  285:18516-18527. 2010
  • Identifying divergent HAMP domains and poly-HAMP chains.  285. 2010
  • Incorporation of tyrosine and glutamine residues into the soluble guanylate cyclase heme distal pocket alters no and o2 binding.  285:17471-17478. 2010
  • Regulation of NT-PGC-1 alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1.  285:18039-18050. 2010
  • A novel cross-talk in diacylglycerol signaling the rac-gap beta 2-chimaerin is negatively regulated by protein kinase c delta-mediated phosphorylation.  285:16931-16941. 2010
  • Discovery of potent and selective inhibitors of Trypanosoma brucei ornithine decarboxylase.  285:16771-16781. 2010
  • Regulation of FGF21 expression and secretion by retinoic acid receptor-related orphan receptor alpha.  285:15668-15673. 2010
  • Structural basis of o(6)-alkylguanine recognition by a bacterial alkyltransferase-like DNA repair protein.  285:13736-13741. 2010
  • Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.  285:13032-13044. 2010
  • Probing DNA- and ATP-mediated conformational changes in the MutS family of mispair recognition proteins using deuterium exchange mass spectrometry.  285:13170-13182. 2010
  • Mechanism of aldolase control of sorting nexin 9 function in endocytosis.  285:11983-11990. 2010
  • Activity-based proteomics of enzyme superfamilies: Serine hydrolases as a case study.  285:11051-11055. 2010
  • Beyond the canonical 20 amino acids: expanding the genetic lexicon.  285:11039-11044. 2010
  • Identification and characterization of the first small molecule inhibitor of MDMX.  285:10786-10796. 2010
  • Repair of o(4)-alkylthymine by o(6)-alkylguanine-DNA alkyltransferases.  285:8185-8195. 2010
  • Alpha 2,6-sialic acid on platelet endothelial cell adhesion molecule (pecam) regulates its homophilic interactions and downstream antiapoptotic signaling.  285:6515-6521. 2010
  • Isolation and characterization of cytoplasmic cofilin-actin rods.  285:5450-5460. 2010
  • Minor modifications of the C-terminal helix reschedule the favored chemical reactions catalyzed by theta class glutathione transferase T1-1.  285:5639-5645. 2010
  • Molecular insights into mammalian end-binding protein heterodimerization.  285:5802-5814. 2010
  • Membrane anchor GTPase-accelerating protein activity of RGS11.G beta(5) complex and accelerates inactivation of the mGluR6-G(o) signaling.  285:4781-4787. 2010
  • Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands.  285:5013-5025. 2010
  • The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.  285:3705-3712. 2010
  • Lys(842) in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin binding, increase FMN shielding, and suppress interflavin electron transfer.  285:3064. 2010
  • Mechanism of Action of an Imidopiperidine Inhibitor of Human Polynucleotide Kinase/Phosphatase.  285:2351-2360. 2010
  • No splicing, no dicing: Non-proteolytic roles of the ubiquitin-proteasome system in transcription.  285:2221-2226. 2010
  • Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast.  285:1909-1918. 2010
  • Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex.  285:1414-1423. 2010
  • N-terminal domains elicit formation of functional Pmel17 amyloid fibrils.  284:35543-35555. 2009
  • Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases.  284:34522-34530. 2009
  • Profiling carbohydrate-receptor interaction with recombinant innate immunity receptor-fc fusion proteins.  284:34479-34489. 2009
  • Lysophosphatidylcholine activates adipocyte glucose uptake and lowers blood glucose levels in murine models of diabetes.  284:33833-33840. 2009
  • Non-classical natural killer T cells modulate plasmid DNA vaccine antigen expression and vaccine-elicited immune responses by MCP-1 secretion after interaction with a beta2-microglobulin-independent CD1d.  284:33800-33806. 2009
  • A human germ line antibody light chain with hydrolytic properties associated with multimerization status.  284:33079-33087. 2009
  • Features of subunit nuom (nd4) in escherichia coli ndh-1 topology and implication of conserved glu(144) for coupling site 1.  284:33062-33069. 2009
  • Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1 alpha.  284:32813-32826. 2009
  • Iso-migrastatin, migrastatin, and dorrigocin production in streptomyces platensis nrrl 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type i polyketide synthase.  284:29746-29756. 2009
  • NET37, a nuclear envelope transmembrane protein with glycosidase homology, is involved in myoblast differentiation.  284:29666-29676. 2009
  • Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis.  284:28968-28976. 2009
  • Nemo-binding domains of both ikkalpha and ikkbeta regulate ikappab kinase complex assembly and classical nf-kappab activation.  284:27596-27608. 2009
  • Solution structure of an ABC collagen heterotrimer reveals a single-register helix stabilized by electrostatic interactions.  284:26851-26859. 2009
  • Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway.  284:25854-25866. 2009
  • In vivo investigation of the roles of fdmm and fdmm1 in fredericamycin biosynthesis unveiling a new family of oxygenases.  284:24735-24743. 2009
  • Porphyrins promote the association of GENOMES UNCOUPLED 4 and a Mg-chelatase subunit with chloroplast membranes.  284:24783-24796. 2009
  • Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.  284:25268-25279. 2009
  • Identification of specific hemopexin-like domain residues that facilitate matrix metalloproteinase collagenolytic activity.  284:24017-24024. 2009
  • Prion protein-detergent micelle interactions studied by NMR in solution.  284:22713-22721. 2009
  • A human embryonic kidney 293T cell line mutated at the Golgi a-mannosidase II locus..  284:21684-21695. 2009
  • Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2.  284:20387-20397. 2009
  • The RNA-induced silencing complex: A versatile gene-silencing machine.  284:17897-17901. 2009
  • Kinome siRNA screen identifies SMG-1 as a negative regulator of hypoxia-inducible factor-1alpha in hypoxia.  284:16752-16758. 2009
  • The isomerase active site of cyclophilin A is critical for hepatitis C virus replication.  284:16998-17005. 2009
  • Opposing roles of peroxisome proliferator-activated receptor alpha and growth hormone in the regulation of CYP4A11 expression in a transgenic mouse model.  284:16541-16552. 2009
  • Increased hydrophobicity at the n terminus/membrane interface impairs gating of the severe combined immunodeficiency-related orai1 mutant.  284:15903-15915. 2009
  • Barx2 controls myoblast fusion and promotes MyoD-mediated activation of the smooth muscle alpha-actin gene.  284:14866-14874. 2009
  • Thioredoxin-related protein 32 is an arsenite-regulated thiol reductase of the proteasome 19 s particle.  284:15233-15245. 2009
  • Budding yeast centrosome duplication requires stabilization of Spc29 via Mps1-mediated phosphorylation.  284:12949-12955. 2009
  • Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-jun N-terminal kinase 3 (JNK3) over p38.  284:12853-12861. 2009
  • Streptococcus pneumoniae endohexosaminidase D, structural and mechanistic insight into substrate-assisted catalysis in family 85 glycoside hydrolases.  284:11676-11689. 2009
  • p38α and p38γ mediate oncogenic ras-induced senescence through differential mechanisms.  284:11237-11246. 2009
  • Critical roles of subunit nuoh (nd1) in the assembly of peripheral subunits with the membrane domain of escherichia coli ndh-1.  284:9814-9823. 2009
  • Functional characterization of tlmk unveiling unstable carbinolamide intermediates in the tallysomycin biosynthetic pathway.  284:8256-8264. 2009
  • An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1.  284:8023-8032. 2009
  • Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity.  284:7068-7077. 2009
  • A novel mode of intervention with serine protease activity: targeting zymogen activation.  284:4647-4657. 2009
  • Rationally designed integrin beta3 mutants stabilized in the high affinity conformation.  284:3917-3924. 2009
  • The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis.  284:3521-3528. 2009
  • An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance.  283:36066-36070. 2008
  • Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class i histone deacetylases.  283:35402-35409. 2008
  • Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance.  283:34687-34695. 2008
  • FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles.  283:34002-34012. 2008
  • Antisense masking reveals contributions of mrna- rrna base pairing to translation of gtx and fgf2 mrnas.  283:33087-33093. 2008
  • The thrombin-sensitive region of protein S mediates phospholipid-dependent interaction with factor Xa.  283:33046-33052. 2008
  • AtNOS/AtNOA1 is a functional Arabidopsis thaliana cGTPase and not a nitric-oxide synthase.  283:32957-32967. 2008
  • BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.  283:32254-32263. 2008
  • The structure of YqeH. An AtNOS1/AtNOA1 ortholog that couples GTP hydrolysis to molecular recognition.  283:32968-32976. 2008
  • Natural homolog of tRNA synthetase editing domain rescues conditional lethality caused by mistranslation.  283:30073-30078. 2008
  • An editing activity that prevents mistranslation and connection to disease.  283:28777-28782. 2008
  • Characterization of the tautomycin biosynthetic gene cluster from streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.  283:28607-28617. 2008
  • In vivo manipulation of the bleomycin biosynthetic gene cluster in streptomyces verticillus atcc15003 revealing new insights into its biosynthetic pathway.  283:28236-28245. 2008
  • Three metal ions participate in the reaction catalyzed by t5 flap endonuclease.  283:28741-28746. 2008
  • Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation.  283:26518-26527. 2008
  • Regulation of cholesterologenesis by the oxysterol receptor, lxr alpha.  283:26332-26339. 2008
  • Iron-sulfur cluster n5 is coordinated by an hxxxcxxcxxxxxc motif in the nuog subunit of escherichia coli nadh : Quinone oxidoreductase (complex i).  283:25979-25987. 2008
  • LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element.  283:22490-22497. 2008
  • Physical and functional interactions of monoubiquitylated transactivators with the proteasome.  283:21789-21798. 2008
  • Histone arg modifications and p53 regulate the expression of okl38, a mediator of apoptosis.  283:20060-20068. 2008
  • Unique small molecule entry inhibitors of hemorrhagic fever arenaviruses.  283:18734-18742. 2008
  • A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function.  283:17250-17259. 2008
  • Determinants of cytochrome P4502C8 substrate binding - structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid.  283:17227-17237. 2008
  • Phosphorylation by casein kinase 1 regulates tonicity-induced osmotic response element-binding protein/tonicity enhancer-binding protein nucleocytoplasmic trafficking.  283:17624-17634. 2008
  • Conformational isomerism can limit antibody catalysis.  283:16554-16560. 2008
  • Detailed mechanisms of the inactivation of factor viiia by activated protein c in the presence of its cofactors, protein s and factor v.  283:16355-16362. 2008
  • Structural and functional characterization of disulfide isoforms of the human IgG2 subclass.  283:16206-16215. 2008
  • Regiospecific o-methylation of naphthoic acids catalyzed by ncsb1, an o-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.  283:14694-14702. 2008
  • Activation domain-dependent monoubiquitylation of Gal4 protein is essential for promoter binding in vivo.  283:12614-12623. 2008
  • Factor Xa active site substrate specificity with substrate phage display and computational molecular modeling.  283:12343-12353. 2008
  • S1P1 receptor localization confers selectivity for Gi mediated cAMP and contractile responses.  283:11954-11963. 2008
  • CO2 fixation kinetics of Halothiobacillus neapolitanus mutant carboxysomes lacking carbonic anhydrase suggest the shell acts as a diffusional barrier for CO2.  283:10377-10384. 2008
  • Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies.  283:10735-10744. 2008
  • Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain.  283:9341-9349. 2008
  • Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.  283:7713-7720. 2008
  • Lysophosphatidic acid receptor-dependent secondary effects via astrocytes promote neuronal differentiation.  283:7470-7479. 2008
  • The SBF- and MBF-associated protein Msa1 is required for proper timing of G(1)-specific transcription in Saccharomyces cerevisiae.  283:6040-6049. 2008
  • Functional role for a conserved aspartate in the spo0e signature motif involved in the dephosphorylation of the bacillus subtilis sporulation regulator spo0a.  283:2962-2972. 2008
  • Evidence for annexin II-S100A10 complex and plasmin in mobilization of cytokine activity of human TrpRS.  283:2070-2077. 2008
  • Human-murine transthyretin heterotetramers are kinetically stable and non-amyloidogenic. A lesson in the generation of transgenic models of diseases involving oligomeric proteins.  283:2098-2107. 2008
  • Alternative splicing minireview series: Combinatorial control facilitates splicing regulation of gene expression and enhances genome diversity.  283:1209-1210. 2008
  • Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening.  283:29-36. 2008
  • Characterization of the nuom (nd4) subunit in escherichia coli ndh-1 - conserved charged residues essential for energy-coupled activities.  282:36914-36922. 2007
  • Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice.  282:36714-36723. 2007
  • Three-dimensional structure of the ephb2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition.  282:36505-36513. 2007
  • Butyl isocyanide as a probe of the activation mechanism of soluble guanylate cyclase.  282:35741-35748. 2007
  • Functional analysis of matrix metalloproteinases and tissue inhibitors of metalloproteinases differentially expressed by variants of human HT-1080 fibrosarcoma exhibiting high and low levels of intravasation and metastasis.  282:35964-35977. 2007
  • Dynamics of the hypoxia-inducible factor-1-vascular endothelial growth factor promoter complex.  282:35035-35045. 2007
  • Activated protein C mutant with minimal anticoagulant activity, normal cytoprotective activity, and preservation of thrombin activable fibrinolysis inhibitor-dependent cytoprotective functions.  282:33022-33033. 2007
  • The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.  282:32243-32255. 2007
  • Circadian transcription depends on limiting amounts of the transcription co-activator nejire/CBP.  282:31349-31357. 2007
  • Factor Va residues 311-325 represent an activated protein C binding region.  282:28353-28361. 2007
  • An activated glutamate residue identified in photosystern II at the interface between the manganese-stabilizing subunit and the D2 polypeptide.  282:27802-27809. 2007
  • Integration of inositol phosphate signaling pathways via human ITPK1.  282:28117-28125. 2007
  • NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus.  282:27562-27571. 2007
  • XRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediates.  282:28004-28013. 2007
  • Coactivators PGC-1 beta and SRC-1 interact functionally to promote the agonist activity of the selective estrogen receptor modulator tamoxifen.  282:26897-26907. 2007
  • Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme a reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of Insigs.  282:27436-27446. 2007
  • A metalloantibody that irreversibly binds a protein antigen.  282:26344-26353. 2007
  • Role of a tRNA base modification and its precursors in frameshifting in eukaryotes.  282:26026-26034. 2007
  • Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity.  282:25416-25424. 2007
  • Identification and characterization of vnx1p, a novel type of vacuolar monovalent cation/h+ antiporter of saccharomyces cerevisiae.  282:24284-24293. 2007
  • Mechanism of cell death caused by complex i defects in a rat dopaminergic cell line.  282:24146-24156. 2007
  • The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.  282:22939-22952. 2007
  • Characterization of a factor Xa binding site on factor Va near the Arg-506 activated protein C cleavage site.  282:21848-21855. 2007
  • Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from streptomyces atroolivaceus s-140 - discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load d-alanine.  282:20273-20282. 2007
  • Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on toll-like receptor 4, cd44, and md-2.  282:18265-18275. 2007
  • Structure of the human lung cytochrome p450 2a13.  282:17306-17313. 2007
  • Escherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivo.  282:16345-16354. 2007
  • Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues.  282:15833-15842. 2007
  • A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein.  282:14309-14315. 2007
  • Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2.  282:14348-14355. 2007
  • Functional analysis of hairpin ribozyme active site architecture.  282:13498-13507. 2007
  • Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase.  282:13033-13046. 2007
  • Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery.  282:11465-11473. 2007
  • Hypoxia-inducible factor 1α (HIF-1α)-mediated hypoxia increases BACE1 expression and β-amyloid generation.  282:10873-10880. 2007
  • Structure and mechanism of Helicobacter pylori fucosyltransferase: a basis for lipopolysaccharide variation and inhibitor design.  282:9973-9982. 2007
  • Interleukin-1-induced NF-kappaB activation is nemo-dependent but does not require IKKbeta.  282:8724-8733. 2007
  • Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics.  282:7254-7264. 2007
  • Neuronal apoptotic signaling pathways probed and intervened by synthetically and modularly modified (SMM) chemokines.  282:7154-7163. 2007
  • Roles of bound quinone in the single subunit nadh-quinone oxidoreductase (ndi1) from saccharomyces cerevisiae.  282:6012-6020. 2007
  • Regulation of human cytochrome P450 4F2 expression by sterol regulatory element-binding protein and lovastatin.  282:5225-5236. 2007
  • Electron nuclear double resonance differentiates complementary roles for active site histidines in (6-4) photolyase.  282:4738-4747. 2007
  • LPA(4)/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing G(s)-, G(q)/G(i)-mediated calcium signaling and G(12/13)-mediated Rho activation.  282:4310-4317. 2007
  • The membrane anchor R7BP controls the proteolytic stability of the striatal specific RGS protein, RGS9-2.  282:4772-4781. 2007
  • Closing the gate to the active site: Effect of the inhibitor methoxyarachidonyl fluorophosphonate on the conformation and membrane binding of fatty acid amide hydrolase.  282:3829-3836. 2007
  • Bacterial flavodoxins support nitric oxide production by bacillus subtilis nitric-oxide synthase.  282:2196-2202. 2007
  • Polo-like kinases inhibited by Wortmannin. Labeling site and downstream effects.  282:2505-2511. 2007
  • Monoclonal antibody clearance. Impact of modulating the interaction of IgG with the neonatal Fc receptor.  282:1709-1717. 2007
  • Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructs.  282:897-907. 2007
  • Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine.  282:1518-1528. 2007
  • Growth hormone corrects proliferation and transcription of phosphoenolpyruvate carboxykinase in livers of old mice via elimination of CCAAT/enhancer-binding protein alpha-Brm complex.  282:1468-1478. 2007
  • The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis.  282:12557-12565. 2007
  • RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.  281:39517-39533. 2006
  • Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8.  281:38653-38662. 2006
  • Structural characterization of spo0e-like protein-aspartic acid phosphatases that regulate sporulation in bacilli.  281:37993-38003. 2006
  • Structural insights into the design of nonpeptidic isothiazolidinone-containing inhibitors of protein-tyrosine phosphatase 1B.  281:38013-38021. 2006
  • A second fatty acid amide hydrolase with variable distribution among placental mammals.  281:36569-36578. 2006
  • Surface charge interactions of the FMN module govern catalysis by nitric-oxide synthase.  281:36819-36827. 2006
  • Trim5α accelerates degradation of cytosolic capsid associated with productive HIV-1 entry.  281:37025-37033. 2006
  • Tropomodulin 3 binds to actin monomers.  281:36454-36465. 2006
  • Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R.  281:34610-34616. 2006
  • Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics.  281:32784-32795. 2006
  • A dedicated phosphopantetheinyl transferase for the fredericamycin polyketide synthase from streptomyces griseus.  281:29660-29668. 2006
  • Substrate specificity of the adenylation enzyme sgcc1 involved in the biosynthesis of the enediyne antitumor antibiotic c-1027.  281:29633-29640. 2006
  • A tyrosine-sulfated peptide derived from the heavy-chain CDR3 region of an HIV-1-neutralizing antibody binds gp120 and inhibits HIV-1 infection.  281:28529-28535. 2006
  • N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways.  281:28822-28830. 2006
  • Structure of a membrane-binding domain from a non-enveloped animal virus - insights into the mechanism of membrane permeability and cellular entry.  281:29278-29286. 2006
  • SUMO-binding motifs mediate the Rad60-dependent response to replicative stress and self-association.  281:27973-27981. 2006
  • Structural and biophysical characterization of the EphB4.ephrinB2 protein-protein interaction and receptor specificity.  281:28185-28192. 2006
  • Widespread, but non-identical, association of proteasomal 19 and 20S proteins with yeast chromatin.  281:27346-27355. 2006
  • Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for α/β-hydrolase 4 in this pathway.  281:26465-26472. 2006
  • Multiple activation mechanisms of p38α mitogen-activated protein kinase.  281:26225-26234. 2006
  • The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae.  281:26289-26297. 2006
  • Reishi polysaccharides induce immunoglobulin production through the tlr4/tlr2-mediated induction of transcription factor blimp-1.  281:24111-24123. 2006
  • GPR92 as a new G12/13 and Gq-coupled lysophosphatidic acid receptor that increases cAMP: LPA5.  281:23589-23597. 2006
  • Nitric oxide binding to prokaryotic homologs of the soluble guanylate cyclase beta 1 h-nox domain.  281:21892-21902. 2006
  • Protective signaling by activated protein C is mechanistically linked to protein C activation on endothelial cells.  281:20077-20084. 2006
  • Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen chlamydia trachomatis by targeting peptide deformylase of the bacterium.  281:16691-16699. 2006
  • Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation.  281:15997-16005. 2006
  • Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor.  281:15951-15958. 2006
  • Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus.  281:15763-15773. 2006
  • Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP.  281:15361-15369. 2006
  • In vivo complementation of complex i by the yeast ndi1 enzyme - possible application for treatment of parkinson disease.  281:14250-14255. 2006
  • Localization of sites of interaction between p23 and hsp90 in solution.  281:14457-14464. 2006
  • Mutational analysis of membrane and soluble forms of human md-2.  281:11955-11964. 2006
  • Fatty acid amide hydrolase determines anandamide-induced cell death in the liver.  281:10431-10438. 2006
  • Structure and reactivity of a thermostable prokaryotic nitric-oxide synthase that forms a long-lived oxy-heme complex.  281:9623-9632. 2006
  • Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1.  281:7717-7726. 2006
  • Construction, affinity maturation, and biological characterization of an anti-tumor-associated glycoprotein-72 humanized antibody.  281:6985-6992. 2006
  • Crystal structure of a bifunctional deaminase and reductase from Bacillus subtilis involved in riboflavin biosynthesis.  281:7605-7613. 2006
  • The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin.  281:7228-7236. 2006
  • The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit.  281:6194-6202. 2006
  • Structure of microsomal cytochrome p4502b4 complexed with the antifungal drug bifonazole - insight into p450 conformational plasticity and membrane interaction.  281:5973-5981. 2006
  • Tab-1 modulates intracellular localization of p38 map kinase and downstream signaling.  281:6087-6095. 2006
  • Beads-on-a-string, characterization of Ets-1 sumoylated within its flexible N-terminal sequence.  281:4164-4172. 2006
  • Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription.  281:99-106. 2006
  • Subcellular targeting and differential s-nitrosylation of endothelial nitric-oxide synthase.  281:151-157. 2006
  • SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells.  281:3198-3203. 2006
  • Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators.  280:43048-43055. 2005
  • Hsk1-Dfp1/Him1, the Cdc7-Dbf4 kinase in Schizosaccharomyces pombe, associates with Swi1, a component of the replication fork protection complex.  280:42536-42542. 2005
  • Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum.  280:40169-40176. 2005
  • Naturally occurring capsid substitutions render HIV-1 cyclophilin A independent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells.  280:40293-40300. 2005
  • The inv(16) cooperates with arf haploinsufficiency to induce acute myeloid leukemia.  280:40097-40103. 2005
  • A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs.  280:39493-39504. 2005
  • C-terminal tail residue Arg(1400) enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase.  280:39208-39219. 2005
  • Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.  280:37616-37622. 2005
  • Gamma-globin gene expression in chemical inducer of dimerization (cid)-dependent multipotential cells established from human beta-globin locus yeast artificial chromosome (beta-yac) transgenic mice.  280:36642-36647. 2005
  • Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor.  280:36047-36054. 2005
  • Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors.  280:35588-35597. 2005
  • Sox9 and p300 cooperatively regulate chromatin-mediated transcription.  280:35203-35208. 2005
  • Structure and lytic activity of a bacillus anthracis prophage endolysin.  280:35433-35439. 2005
  • Down-regulation of factor IXa in the factor Xase complex by protein Z-dependent protease inhibitor.  280:33819-33825. 2005
  • Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex.  280:34278-34287. 2005
  • A peptide core motif for binding to heterotrimeric G protein α subunits.  280:32057-32060. 2005
  • Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.  280:31405-31412. 2005
  • Structures of tryptophanyl-tRNA synthetase II from Deinococcus radiodurans bound to ATP and tryptophan. Insight into subunit cooperativity and domain motions linked to catalysis.  280:31965-31973. 2005
  • Preponderance of free mediator in the yeast Saccharomyces cerevisiae.  280:31200-31207. 2005
  • Structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase CheA.  280:30581-30585. 2005
  • Translocation of dynorphin neuropeptides across the plasma membrane - a putative mechanism of signal transmission.  280:26360-26370. 2005
  • O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.  280:25313-25322. 2005
  • Crystallin gamma B-I4F mutant protein binds to alpha-crystallin and affects lens transparency.  280:25071-25078. 2005
  • Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor.  280:24792-24803. 2005
  • X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease.  280:23815-23819. 2005
  • Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites.  280:22962-22967. 2005
  • The serine-rich domain from Crk-associated substrate (p130cas) is a four-helix bundle.  280:21908-21914. 2005
  • Cvak104 is a novel poly-l-lysine-stimulated kinase that targets the beta 2-subunit of ap2.  280:21539-21544. 2005
  • Protease-activated receptor-1 signaling by activated protein c in cytokine-perturbed endothelial cells is distinct from thrombin signaling.  280:19808-19814. 2005
  • Tetrameric architecture of the circadian clock protein KaiB - a novel interface for intermolecular interactions and its impact on the circadian rhythm.  280:19127-19135. 2005
  • Potent glycan inhibitors of myelin-associated glycoprotein enhance axon outgrowth in vitro.  280:16305-16310. 2005
  • External GTP-bound transglutaminase 2 is a molecular switch for chondrocyte hypertrophic differentiation and calcification.  280:15004-15012. 2005
  • Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma 2.  280:14656-14662. 2005
  • Crystal structure of the cysteine-rich secretory protein stecrisp reveals that the cysteine-rich domain has a k(+) channel inhibitor-like fold.  280:12405-12412. 2005
  • Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells.  280:10564-10571. 2005
  • The three nitric-oxide synthases differ in their kinetics of tetrahydrobiopterin radical formation, heme-dioxy reduction, and arginine hydroxylation.  280:8929-8935. 2005
  • Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence.  280:8443-8451. 2005
  • In vivo cleavage of alpha 2,6-sialyltransferase by alzheimer beta-secretase.  280:8589-8595. 2005
  • Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment.  280:8343-8350. 2005
  • The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor.  280:8060-8068. 2005
  • Bacteriophage P22 tail accessory factor GP26 is a long triple-stranded coiled-coil.  280:5929-5933. 2005
  • R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family.  280:5133-5136. 2005
  • C-terminal ecfp fusion impairs synaptotagmin 1 function - crowding out synaptotagmin 1.  280:5089-5100. 2005
  • Conformational flexibility in crystal structures of human 11 β-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation.  280:4639-4648. 2005
  • Exploring strategies for the design of artificial transcription factors.  280:3707-3714. 2005
  • A major histocompatibility complex-peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes - crystal structure of human leukocyte antigen (hla)-a1-mage-a1 in complex with fab-hyb3.  280:2972-2980. 2005
  • VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function.  280:2405-2408. 2005
  • Characterization of the iron-sulfur cluster n7 (n1c) in the subunit nuog of the proton-translocating nadh-quinone oxidoreductase from escherichia coli.  280:301-307. 2005
  • Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex.  279:55754-55759. 2004
  • DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe.  279:53023-53027. 2004
  • Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening.  279:50555-50565. 2004
  • Neural cell adhesion molecule (n-cam) homophilic binding mediated by the two n-terminal ig domains is influenced by intramolecular domain-domain interactions.  279:49633-49643. 2004
  • Regioselective nitration of tryptophan by a complex between bacterial nitric-oxide synthase and tryptophanyl-tRNA synthetase.  279:49567-49570. 2004
  • Translation of a yeast mitochondrial tRNA synthetase initiated at redundant non-AUG codons.  279:49656-49663. 2004
  • Factor XI interacts with the leucine-rich repeats of glycoprotein Ib alpha on the activated platelet.  279:49323-49329. 2004
  • Prothrombin residues 473-487 contribute to factor Va binding in the prothrombinase complex.  279:49019-49025. 2004
  • Structural and dynamic independence of isopeptide-linked RanGAP1 and SUMO-1.  279:49131-49137. 2004
  • The NS5A protein of hepatitis C virus is a zinc metalloprotein.  279:48576-48587. 2004
  • Reaction intermediates in the catalytic mechanism of escherichia coli muty DNA glycosylase.  279:46930-46939. 2004
  • Global analysis of protein sumoylation in Saccharomyces cerevisiae.  279:45662-45668. 2004
  • Negative regulation of t cell receptor signaling by siglec-7 (p70/airm) and siglec-9.  279:43117-43125. 2004
  • The stability of the nuclear lamina polymer changes with the composition of lamin subtypes according to their individual binding strengths.  279:42811-42817. 2004
  • Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.  279:40337-40344. 2004
  • Dynamin gtpase domain mutants that differentially affect gtp binding, gtp hydrolysis, and clathrin-mediated endocytosis.  279:40431-40436. 2004
  • Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2.  279:38409-38414. 2004
  • The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05 Å resolution.  279:38091-38094. 2004
  • Plasmin-induced migration requires signaling through protease-activated receptor 1 and integrin alpha(9)beta(1).  279:37528-37534. 2004
  • Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase.  279:37918-37927. 2004
  • Peanut agglutinin high phenotype of activated cd8(+) t cells results from de novo synthesis of cd45 glycans.  279:36689-36697. 2004
  • Cds1 phosphorylation by Rad3-Rad26 kinase is mediated by forkhead-associated domain interaction with Mrc1.  279:32079-32086. 2004
  • Functional roles of four conserved charged residues in the membrane domain subunit nuoa of the proton-translocating nadh-quinone oxidoreductase from escherichia coli.  279:32360-32366. 2004
  • The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme.  279:32684-32691. 2004
  • A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis.  279:29615-29621. 2004
  • Trans-inactivation of receptor tyrosine kinases by novel angiotensin ii at2 receptor-interacting protein, atip.  279:28989-28997. 2004
  • Intermediate trapping on a mutant retaining alpha-galactosyltransferase identifies an unexpected aspartate residue.  279:28339-28344. 2004
  • Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3).  279:27633-27645. 2004
  • Quantitative proteomics of the thyroid hormone receptor-coregulator interactions.  279:27584-27590. 2004
  • Structural basis for amplifying vinculin activation by talin.  279:27667-27678. 2004
  • Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding.  279:27294-27301. 2004
  • Interaction interface of human flap endonuclease-1 with its DNA substrates.  279:24394-24402. 2004
  • Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica.  279:24197-24202. 2004
  • Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain.  279:23038-23044. 2004
  • Bacillus subtilis chec and fliy are members of a novel class of chey-p-hydrolyzing proteins in the chemotactic signal transduction cascade.  279:21787-21792. 2004
  • Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.  279:22331-22346. 2004
  • The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1.  279:22595-22604. 2004
  • Lysophospholipid G protein-coupled receptors.  279:20555-20558. 2004
  • Molecular and functional differences induced in thrombospondin-1 by the single nucleotide polymorphism associated with the risk of premature, familial myocardial infarction.  279:21651-21657. 2004
  • Activation of the redox-regulated chaperone hsp33 by domain unfolding.  279:20529-20538. 2004
  • A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles.  279:19018-19025. 2004
  • Control of the vascular endothelial growth factor internal ribosome entry site (IRES) activity and translation initiation by alternatively spliced coding sequences.  279:18717-18726. 2004
  • P21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized RHO exchange factor.  279:18392-18400. 2004
  • Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates.  279:18034-18045. 2004
  • Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation.  279:17283-17288. 2004
  • Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.  279:17634-17639. 2004
  • Interaction of estrogen receptor alpha with 3-methyladenine DNA glycosylase modulates transcription and DNA repair.  279:16875-16882. 2004
  • Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor.  279:14509-14519. 2004
  • Identification of novel binding elements and gene targets for the homeodomain protein BARX2.  279:14520-14530. 2004
  • TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae.  279:14752-14762. 2004
  • Cell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase.  279:14245-14255. 2004
  • Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate.  279:13839-13848. 2004
  • Sphingolipids as bioactive regulators of thrombin generation.  279:12036-12042. 2004
  • Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation.  279:10564-10574. 2004
  • Functional role of the lock and key motif at the subunit interface of glutathione transferase P1-1.  279:9586-9596. 2004
  • Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis.  279:8526-8529. 2004
  • Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity.  279:8111-8115. 2004
  • Identification of four genes necessary for biosynthesis of the modified nucleoside queuosine.  279:6280-6285. 2004
  • Amino acid substitution at the dimeric interface of human manganese superoxide dismutase.  279:5861-5866. 2004
  • Assembly of respiratory complexes i, iii, and iv into nadh oxidase supercomplex stabilizes complex i in paracoccus denitrificans.  279:5000-5007. 2004
  • Kinetic and stability properties of Penicillium chrysogenum ATP sulfurylase missing the C-terminal regulatory domain.  279:4415-4424. 2004
  • Structure-activity relationship of synthetic toll-like receptor 4 agonists.  279:4440-4449. 2004
  • A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2.  279:3197-3201. 2004
  • C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism.  279:3817-3827. 2004
  • Interaction of the taz1 domain of the creb-binding protein with the activation domain of cited2 - regulation by competition between intrinsically unstructured ligands for non-identical binding sites.  279:3042-3049. 2004
  • Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse.  279:1581-1584. 2004
  • Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling.  279:2125-2134. 2004
  • Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription.  279:1867-1871. 2004
  • High intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts.  279:1050-1059. 2004
  • The transcriptional repressor STRA13 regulates a subset of peripheral circadian outputs.  279:1141-1150. 2004
  • Induced fit movements and metal cofactor selectivity of class ll aldolases - structure of Thermus aquaticus fructose-1,6-bisphosphate aldolase.  279:11825-11833. 2004
  • Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site.  279:9497-9503. 2004
  • The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0 Å resolution.  279:35630-35637. 2004
  • Expression profiling identifies genes that continue to respond to insulin in adipocytes made insulin-resistant by treatment with tumor necrosis factor-alpha.  278:52298-52306. 2003
  • Identification of drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions.  278:52172-52178. 2003
  • Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity - Different oligomers activate different signal transduction pathways.  278:50810-50817. 2003
  • Bacillus subtilis hydrolyzes chey-p at the location of its action, the flagellar switch.  278:48611-48616. 2003
  • Intradiabodies, bispecific, tetravalent antibodies for the simultaneous functional knockout of two cell surface receptors.  278:47812-47819. 2003
  • Sphingosine kinase type 1 induces G12/13-mediated stress fiber formation, yet promotes growth and survival independent of G protein-coupled receptors.  278:46452-46460. 2003
  • Essential glycine in the proton channel of escherichia coli transhydrogenase.  278:45333-45339. 2003
  • Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex.  278:45460-45467. 2003
  • Structure-specific tRNA determinants for editing a mischarged amino acid.  278:45056-45061. 2003
  • Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappa B independently of platelet-activating factor.  278:45034-45039. 2003
  • Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns.  278:42750-42760. 2003
  • Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases.  278:42020-42026. 2003
  • Crystal structure of Pasteurella haemolytica ferric ion-binding protein a reveals a novel class of bacterial iron-binding proteins.  278:41093-41098. 2003
  • Convulxin binds to native, human glycoprotein IIbα.  278:39452-39460. 2003
  • Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.  278:40330-40336. 2003
  • Tropomodulin contains two actin filament pointed end-capping domains.  278:40000-40009. 2003
  • Pharmacogenomic analysis of mechanisms mediating ethanol regulation of dopamine beta-hydroxylase.  278:38860-38869. 2003
  • delta BAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF.  278:38220-38228. 2003
  • Evidence for distinct roles in catalysis for residues of the serine-serine-lysine catalytic triad of fatty acid amide hydrolase.  278:37393-37399. 2003
  • Sulfation of tyrosine 174 in the human C3a receptor is essential for binding of C3a anaphylatoxin.  278:37902-37908. 2003
  • Nanomolar affinity small molecule correctors of defective ΔF508-CFTR chloride channel gating.  278:35079-35085. 2003
  • GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2.  278:34641-34653. 2003
  • The internal ribosome entry site (ires) contained within the rna-binding motif protein 3 (rbm3) mrna is composed of functionally distinct elements.  278:33793-33800. 2003
  • Identification of distinct sequences in human blood coagulation factor Xa and prothrombin essential for substrate and cofactor recognition in the prothrombinase complex.  278:33312-33318. 2003
  • Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells.  278:31426-31433. 2003
  • Sialoside specificity of the siglec family assessed using novel multivalent probes - identification of potent inhibitors of myelin-associated glycoprotein.  278:31007-31019. 2003
  • The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation.  278:30854-30858. 2003
  • Critical role of integrin alpha 5 beta 1 in urokinase (uPA)/urokinase receptor (uPAR, CD87) signaling.  278:29863-29872. 2003
  • Lipopolysaccharide (lps)-binding protein inhibits responses to cell-bound lps.  278:28367-28371. 2003
  • IKKi/IKK epsilon plays a key role in integrating signals induced by pro-inflammatory stimuli.  278:26612-26619. 2003
  • Transcriptional co-activators CREB-binding protein and p300 regulate chondrocyte-specific gene expression via association with Sox9.  278:27224-27229. 2003
  • BACE1- and BACE2-expressing human cells - characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors.  278:25859-25866. 2003
  • Apolipoprotein a-ii inhibits high density lipoprotein remodeling and lipid-poor apolipoprotein a-i formation.  278:22530-22536. 2003
  • Curariform antagonists bind in different orientations to acetylcholine-binding protein.  278:23020-23026. 2003
  • The role of dipeptidyl peptidase IV in the cleavage of glucagon family peptides: in vivo metabolism of pituitary adenylate cyclase-activating polypeptide-(1-38).  278:22418-22423. 2003
  • κB-Ras binds to the unique insert within the ankyrin repeat domain of IκBβ and regulates cytoplasmic retention of IκBβ·NF-κB complexes.  278:23101-23106. 2003
  • Secretory iga n- and o-glycans provide a link between the innate and adaptive immune systems.  278:20140-20153. 2003
  • Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase 1/erk5 but not erk1/2 kinase activation.  278:18682-18688. 2003
  • Characterization of cluster n5 as a fast-relaxing 4fe-4s cluster in the nqo3 subunit of the proton-translocating nadh-ubiquinone oxidoreductase from paracoccus denitrificans.  278:15514-15522. 2003
  • Synergy of silent and hot spot mutations in importin beta reveals a dynamic mechanism for recognition of a nuclear localization signal.  278:16216-16221. 2003
  • Glucosylceramide, a neutral glycosphingolipid anticoagulant cofactor, enhances the interaction of human- and bovine-activated protein C with negatively charged phospholipid vesicles.  278:14614-14621. 2003
  • Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways.  278:8904-8912. 2003
  • Protection of islets by in situ peptide-mediated transduction of the I kappa B kinase inhibitor nemo-binding domain peptide.  278:9862-9868. 2003
  • The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II.  278:8897-8903. 2003
  • The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERR alpha).  278:9013-9018. 2003
  • Co-translational targeting and translocation of the amino terminus of opsin across the endoplasmic membrane requires gtp but not atp.  278:7920-7926. 2003
  • Identification of residues in glutathione transferase capable of driving functional diversification in evolution - A novel approach to protein redesign.  278:8733-8738. 2003
  • Ligand and coactivator identity determines the requirement of the charge clamp for coactivation of the peroxisome proliferator-activated receptor gamma.  278:8637-8644. 2003
  • The homeodomain protein barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors.  278:8269-8278. 2003
  • Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha.  278:7413-7421. 2003
  • Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor.  278:3378-3385. 2003
  • A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (ppar alpha) versus liver x receptor.  278:2403-2410. 2003
  • Adp-ribosylation factor 4 small gtpase mediates epidermal growth factor receptor-dependent phospholipase d2 activation.  278:2661-2668. 2003
  • Observation of an arsenic adduct in an acetyl esterase crystal structure.  278:2008-2014. 2003
  • Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.  278:1131-1136. 2003
  • Contribution of glycine 146 to a conserved folding module affecting stability and refolding of human glutathione transferase P1-1.  278:1291-1302. 2003
  • Proteomic characterization of the Chlamydomonas reinhardtii chloroplast ribosome. Identification of proteins unique to th e70 S ribosome.  278:33774-33785. 2003
  • A single-domain cyclophilin from Leishmania donovani reactivates soluble aggregates of adenosine kinase by isomerase-independent chaperone function.  277:47451-47460. 2002
  • Protein-rna interactions and virus stability as probed by the dynamics of tryptophan side chains.  277:47596-47602. 2002
  • Genetic code ambiguity. Cell viability related to the severity of editing defects in mutant tRNA synthetases.  277:45729-45733. 2002
  • Localization of carbohydrate attachment sites and disulfide bridges in limulus alpha(2)-macroglobulin - evidence for two forms differing primarily in their bait region sequences.  277:43698-43706. 2002
  • Cooperativity in transcription factor binding to the coactivator creb-binding protein (cbp) - the mixed lineage leukemia protein (mll) activation domain binds to an allosteric site on the kix domain.  277:43168-43174. 2002
  • Roles of phosphorylation and helix propensity in the binding of the kix domain of creb-binding protein by constitutive (c-myb) and inducible (creb) activators.  277:42241-42248. 2002
  • Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein.  277:41299-41302. 2002
  • Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.  277:40181-40184. 2002
  • Tyrosine-sulfated peptides functionally reconstitute a CCR5 variant lacking a critical amino-terminal region.  277:40397-40402. 2002
  • Immunosuppressive effects of glucosamine.  277:39343-39349. 2002
  • Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase.  277:38870-38876. 2002
  • Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression.  277:38579-38588. 2002
  • Stimulation of enveloped virus infection by beta-amyloid fibrils.  277:35019-35024. 2002
  • The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands.  277:35105-35112. 2002
  • Plasmin-induced migration of endothelial cells. A potential target for the anti-angiogenic action of angiostatin.  277:33564-33570. 2002
  • The proton channel of the energy-transducing nicotinamide nucleotide transhydrogenase of escherichia coli.  277:33670-33675. 2002
  • Noncatalytic domains of RGS9-1.Gbeta 5L play a decisive role in establishing its substrate specificity.  277:32843-32848. 2002
  • Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits reverse transcription and viral replication.  277:32036-32045. 2002
  • Regulated expression of the apolipoprotein e/c-i/c-iv/c-ii gene cluster in murine and human macrophages - a critical role for nuclear liver x receptors alpha and beta.  277:31900-31908. 2002
  • Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III.  277:31020-31030. 2002
  • Ilpip, a novel anti-apoptotic protein that enhances xiap-mediated activation of jnk1 and protection against apoptosis.  277:30454-30462. 2002
  • Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate.  277:30208-30218. 2002
  • Oligomerization state-dependent activation of NF-NF-κB signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30).  277:29359-29362. 2002
  • The role of post-translational modifications of the CXCR4 amino terminus in stromal-derived factor 1 alpha association and HIV-1 entry.  277:29484-29489. 2002
  • Transmutation of human glutathione transferase A2-2 with peroxidase activity into an efficient steroid isomerase.  277:30019-30022. 2002
  • Molecular characterization of an extended binding site for coagulation factor Va in the positive exosite of activated protein C.  277:28836-28840. 2002
  • Identification of the disulfide bonds in the recombinant somatomedin B domain of human vitronectin.  277:27109-27119. 2002
  • Cyclin I is an RS domain protein involved in pre-mRNA splicing.  277:25465-25473. 2002
  • Identification of the tRNA-dihydrouridine synthase family.  277:25090-25095. 2002
  • Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1p) receptors, S1p(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3.  277:25152-25159. 2002
  • Novel isoform of insulin receptor substrate p53/p58 is generated by alternative splicing in the crib/sh3-binding region.  277:24728-24734. 2002
  • Specific binding of RGS9-G beta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activity.  277:24376-24381. 2002
  • Kinetic mechanism of activation of the cdk2/cyclin a complex.  277:23847-23853. 2002
  • Active site residues of cyclophilin A are crucial for its signaling activity via CD147.  277:22959-22965. 2002
  • Unique ability of integrin alpha(v)beta(3) to support tumor cell arrest under dynamic flow conditions.  277:21930-21938. 2002
  • Biochemical characterization of aspartyl phosphate phosphatase interaction with a phosphorylated response regulator and its inhibition by a pentapeptide.  277:20483-20489. 2002
  • Induction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase.  277:20124-20126. 2002
  • Plasticity of recognition of the 3'-end of mischarged tRNA by class I aminoacyl-tRNA synthetases.  277:20510-20517. 2002
  • Effects of nitroglycerin on soluble guanylate cyclase: Implications for nitrate tolerance.  277:18253-18256. 2002
  • Active-site residues governing high steroid isomerase activity in human glutathione transferase A3-3.  277:16648-16654. 2002
  • Peroxisome proliferator-activated receptor (ppar) gamma coactivator-1 recruitment regulates ppar subtype specificity.  277:16750-16757. 2002
  • Loss of p53 compensates for alpha(v)-integrin function in retinal neovascularization.  277:13371-13374. 2002
  • The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha.  277:13918-13925. 2002
  • Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha(IIb)beta(3).  277:11949-11956. 2002
  • Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway.  277:11401-11409. 2002
  • Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization.  277:10394-10399. 2002
  • Processing of integrin αv subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase.  277:9749-9756. 2002
  • Kinetic analysis of the interaction between vitronectin and the urokinase receptor.  277:9395-9404. 2002
  • Neutral glycosphingolipid-dependent inactivation of coagulation factor Va by activated protein C and protein S.  277:8861-8865. 2002
  • Requirement of helix 1 and the af-2 domain of the thyroid hormone receptor for coactivation by pgc-1.  277:8898-8905. 2002
  • The hemopexin-like C-terminal domain of membrane type 1 matrix metalloproteinase regulates proteolysis of a multifunctional protein, gC1qR.  277:9318-9325. 2002
  • A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells.  277:7420-7429. 2002
  • An alternative processing of integrin αv subunit in tumor cells by membrane type-1 matrix metalloproteinase.  277:7377-7385. 2002
  • Azotobacter vinelandii ferredoxin i - a sequence and structure comparison approach to alteration of 4fe-4s 2(+/+) reduction potential.  277:5603-5610. 2002
  • Axonin-1/TAG-1 mediates cell-cell adhesion by a cis-assisted trans-interaction.  277:4551-4557. 2002
  • Pgc-1 functions as a transcriptional coactivator for the retinoid x receptors.  277:3913-3917. 2002
  • Misexpression of the eyes absent family triggers the apoptotic program.  277:3560-3567. 2002
  • Substitution of ribonucleotides in the T7 RNA polymerase promoter element.  277:2987-2991. 2002
  • Characterization of the iron-sulfur cluster coordinated by a cysteine cluster motif (cxxcxxxcx27c) in the nqo3 subunit in the proton-translocating nadh-quinone oxidoreductase (ndh-1) of thermus thermophilus hb-8.  277:1680-1688. 2002
  • Focal adhesion kinase and mitogen-activated protein kinases are involved in chondrocyte activation by the 29-kDa amino-terminal fibronectin fragment.  277:907-911. 2002
  • Md-2 and tlr4 n-linked glycosylations are important for a functional lipopolysaccharide receptor.  277:1845-1854. 2002
  • A catalytic antibody produces fluorescent tracers of gap junction communication in living cells.  276:49164-49168. 2001
  • Circadian regulation of diverse gene products revealed by mRNA expression profiling of synchronized fibroblasts.  276:46751-46758. 2001
  • Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins b cell linker protein and slp-76 in lymphocytes.  276:45207-45216. 2001
  • In vitro analysis of nuclear transport mediated by the c-terminal shuttle domain of tap.  276:42355-42363. 2001
  • The low density lipoprotein receptor-related protein/alpha(2)-macroglobulin receptor is a receptor for connective tissue growth factor.  276:40659-40667. 2001
  • Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells.  276:39562-39568. 2001
  • Lack of complex i activity in human cells carrying a mutation in mtdna-encoded nd4 subunit is corrected by the saccharomyces cerevisiae nadh-quinone oxidoreductase (ndi1) gene.  276:38808-38813. 2001
  • Md-2 binds to bacterial lipopolysaccharide.  276:38044-38051. 2001
  • A 5' leader of Rbm3, a cold stress-induced mRNA, mediates internal initiation of translation with increased efficiency under conditions of mild hypothermia.  276:36917-36922. 2001
  • Rgs9-g beta 5 substrate selectivity in photoreceptors - opposing effects of constituent domains yield high affinity of rgs interaction with the g protein-effector complex.  276:37365-37372. 2001
  • Human glutathione transferase Al-1 demonstrates both half-of-the-sites and all-of-the-sites reactivity.  276:35599-35605. 2001
  • Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, lPB3/EDG-3.  276:33697-33704. 2001
  • Transcriptional coactivator protein p300 - kinetic characterization of its histone acetyltransferase activity.  276:33721-33729. 2001
  • Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones.  276:33061-33065. 2001
  • The LG3 module of laminin-5 harbors a binding site for integrin α3β1 that promotes cell adhesion, spreading, and migration.  276:33045-33053. 2001
  • The folding and stability of human alpha class glutathione transferase A1-1 depend on distinct roles of a conserved N-capping box and hydrophobic staple motif.  276:32177-32183. 2001
  • The gal4 activation domain binds sug2 protein, a proteasome component, in vivo and in vitro.  276:30956-30963. 2001
  • C-myc-mediated regulation of telomerase activity is disabled in immortalized cells.  276:29994-30001. 2001
  • Development of zinc finger domains for recognition of the 5 '-ann-3 ' family of DNA sequences and their use in the construction of artificial transcription factors.  276:29466-29478. 2001
  • Lung Kruppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase.  276:29299-29306. 2001
  • Mutations in the G-domain of elongation factor G from thermus thermophilus affect both its interaction with GTP and fusidic acid.  276:28774-28778. 2001
  • Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks.  276:29282-29291. 2001
  • Identification of a motif in the carboxyl terminus of β-arrestin2 responsible for activation of JNK3.  276:27770-27777. 2001
  • Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor a in HepG2 cells.  276:27950-27958. 2001
  • The mechanism of the remodeling of high density lipoproteins by phospholipid transfer protein.  276:26898-26905. 2001
  • Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.  276:26004-26011. 2001
  • Expression and function of lysophosphatidic acid receptors in cultured rodent microglial cells.  276:25946-25952. 2001
  • Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.  276:25705-25714. 2001
  • Proteolytic cleavage of chromogranin A (CgA) by plasmin. Selective liberation of a specific bioactive CgA fragment that regulates catecholamine release.  276:25022-25029. 2001
  • Molecular mechanism of aminoglycoside antibiotic kinase aph(3 ')-iiia - roles of conserved active site residues.  276:23929-23936. 2001
  • Demonstration of direct effects of growth hormone on neonatal cardiomyocytes.  276:22892-22900. 2001
  • Unique pathway of thrombin-induced platelet aggregation mediated by glycoprotein Ib.  276:21173-21183. 2001
  • Caspase remodeling of the spectrin membrane skeleton during lens development and aging.  276:20735-20742. 2001
  • Conversion of Glu-plasminogen to Lys-plasminogen is necessary for optimal stimulation of plasminogen activation on the endothelial cell surface.  276:19078-19083. 2001
  • JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase.  276:18855-18862. 2001
  • Structural and functional identification of major histocompatibility complex class i-restricted self-peptides as naturally occurring molecular mimics of viral antigens - possible role in cd8(+) t cell-mediated, virus-induced autoimmune disease.  276:19396-19403. 2001
  • Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion.  276:18415-18422. 2001
  • Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain.  276:17958-17967. 2001
  • Regulation of von Willebrand factor binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal.  276:16952-16959. 2001
  • P53 latency - c-terminal domain prevents binding of p53 core to target but not to nonspecific DNA sequences.  276:15650-15658. 2001
  • Conserved cysteines in the sialyltransferase sialylmotifs form an essential disulfide bond.  276:15200-15207. 2001
  • Two novel xenopus homologs of mammalian lPA1/EDG-2 function as lysophosphatidic acid receptors in xenopus oocytes and mammalian cells.  276:15208-15215. 2001
  • Stimulation of nuclear export and inhibition of nuclear import by a ran mutant deficient in binding to ran-binding protein 1.  276:14524-14531. 2001
  • The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif.  276:13314-13321. 2001
  • Fragile T-stem in disease-associated human mitochondrial tRNA sensitizes structure to local and distant mutations.  276:10607-10611. 2001
  • Molecular cloning of mouse erk5/bmk1 splice variants and characterization of erk5 functional domains.  276:10870-10878. 2001
  • Receptor and membrane recycling can occur with unaltered efficiency despite dramatic rab5(q79l)-induced changes in endosome geometry.  276:9649-9654. 2001
  • Role of zymogen and activated factor x as scaffolds for the inhibition of the blood coagulation factor viia-tissue factor complex by recombinant nematode anticoagulant protein c2.  276:10063-10071. 2001
  • Bmk1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase.  276:8631-8634. 2001
  • Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane ss-sheet from a prepore intermediate.  276:8261-8268. 2001
  • Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III.  276:8231-8238. 2001
  • PU.1 is a lineage-specific regulator of tyrosine phosphatase CD45.  276:7637-7642. 2001
  • Recombinant cytochrome rc(557) obtained from escherichia coli cells expressing a truncated thermus thermophilus cyca gene - heme inversion in an improperly matured protein.  276:6537-6544. 2001
  • Residue met(156) contributes to the labile enzyme conformation of coagulation factor viia.  276:6616-6620. 2001
  • Yeast glyoxalase I is a monomeric enzyme with two active sites.  276:1845-1849. 2001
  • Type ii transmembrane serine proteases - insights into an emerging class of cell surface proteolytic enzymes.  276:857-860. 2001
  • Purification, cloning, and characterization of a profibrinolytic plasminogen-binding protein, TIP49a.  276:179-186. 2001
  • Reconstitution of pterin-free inducible nitric-oxide synthase.  276:421-427. 2001
  • The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments.  276:583-592. 2001
  • Characterization of inherited differences in transcription of the human integrin alpha(2) gene.  276:23518-23524. 2001
  • Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7α-hydroxylase.  276:23304-23311. 2001
  • Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2.  276:21129-21135. 2001
  • Operational RNA code for amino acids in relation to genetic code in evolution.  276:6881-6884. 2001
  • The isolation, characterization, and molecular cloning of a 75-kda gelatinase b-like enzyme, a member of the matrix metalloproteinase (mmp) family - an avian enzyme that is mmp-9-like in its cell expression pattern but diverges from mammalian gelatinase b in sequence and biochemical properties.  275:40827-40838. 2000
  • The mechanism of action of inhibitors of bacterial two-component signal transduction systems.  275:38900-38904. 2000
  • Serine 727 phosphorylation and activation of cytosolic phospholipase A(2) by MNK1-related protein kinases.  275:37542-37551. 2000
  • Use of the nadh-quinone oxidoreductase (ndi1) gene of saccharomyces cerevisiae as a possible cure for complex i defects in human cells.  275:37774-37778. 2000
  • Protection of human islets from the effects of interleukin-1 beta by adenoviral gene transfer of an I kappa B repressor.  275:36509-36513. 2000
  • Structure of c42d azotobacter vinelandii fdi - a cys-x-x-asp-x-x-cys motif ligates an air-stable 4fe-4s (2+/+) cluster.  275:36974-36983. 2000
  • Domain III of elongation factor G from thermus thermophilus is essential for induction of GTP hydrolysis on the ribosome.  275:35820-35824. 2000
  • Generation and characterization of a recombinant human CCR5-specific antibody. A phage display approach for rabbit antibody humanization.  275:36073-36078. 2000
  • Induction of positive cooperativity by amino acid replacements within the C-terminal domain of penicillium chrysogenum ATP sulfurylase.  275:36303-36310. 2000
  • Kinase signaling initiates coat complex II (COPII) recruitment and export from the mammalian endoplasmic reticulum.  275:35673-35676. 2000
  • Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase.  275:35734-35737. 2000
  • The uncoupling protein-3 gene is transcribed from tissue-specific promoters in humans but not in rodents.  275:36394-36399. 2000
  • A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry.  275:33516-33521. 2000
  • Chemically regulated zinc finger transcription factors.  275:32617-32627. 2000
  • A cdc6 protein-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor.  275:32098-32105. 2000
  • Biochemical characterization of the tata-binding protein-gal4 activation domain complex.  275:31914-31920. 2000
  • Chopper, a new death domain of the p75 neurotrophin receptor that mediates rapid neuronal cell death.  275:30537-30545. 2000
  • Exosite interactions determine the affinity of factor x for the extrinsic xase complex.  275:28826-28833. 2000
  • Substituting selenocysteine for catalytic cysteine 41 enhances enzymatic activity of plant phospholipid hydroperoxide glutathione peroxidase expressed in escherichia coli.  275:28715-28721. 2000
  • One of two genes encoding glycyl-tRNA synthetase in Saccharomyces cerevisiae provides mitochondrial and cytoplasmic functions.  275:27681-27688. 2000
  • Torsin A and its torsion dystonia-associated mutant forms are lumenal glycoproteins that exhibit distinct subcellular localizations.  275:27933-27939. 2000
  • The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7.  275:26661-26664. 2000
  • Kinetic and spectroscopic evidence for three actomyosin : Adp states in smooth muscle.  275:25418-25426. 2000
  • Regulation of transporter associated with antigen processing by phosphorylation.  275:24130-24135. 2000
  • Clarifying the catalytic roles of conserved residues in the amidase signature family.  275:19177-19184. 2000
  • Big mitogen-activated kinase regulates multiple members of the mef2 protein family.  275:18534-18540. 2000
  • Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.  275:18108-18113. 2000
  • Phosphorylation of the nuclear transport machinery down-regulates nuclear protein import in vitro.  275:17848-17856. 2000
  • Functional redundancy in the nonspecific RNA binding domain of a class I tRNA synthetase.  275:17180-17186. 2000
  • Virus maturation targets the protein capsid to concerted disassembly and unfolding.  275:16037-16043. 2000
  • Peptides selected to bind the ga180 repressor are potent transcriptional activation domains in yeast.  275:14979-14984. 2000
  • Association of p130(cas) with phosphatidylinositol-3-oh kinase mediates adenovirus cell entry.  275:14729-14735. 2000
  • Cu2+ and zn2+ inhibit nitric-oxide synthase through an interaction with the reductase domain.  275:14070-14076. 2000
  • Functional cloning of an Arabidopsis thaliana cDNA encoding cycloeucalenol cycloisomerase.  275:13394-13397. 2000
  • Monitoring enzyme catalysis with mass spectrometry.  275:13455-13459. 2000
  • The rabbit antibody repertoire as a novel source for the generation of therapeutic human antibodies.  275:13668-13676. 2000
  • Inactivation of active thrombin-activable fibrinolysis inhibitor takes place by a process that involves conformational instability rather than proteolytic cleavage.  275:12410-12415. 2000
  • Modeling and functional analysis of the interaction between von Willebrand factor A1 domain and glycoprotein Ib alpha.  275:12763-12768. 2000
  • Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (cacna2d2).  275:12237-12242. 2000
  • Multiple o-glycoforms on the spore coat protein sp96 in dictyostelium discoideum - fuc(alpha 1-3)glcnac-alpha-1-p-ser is the major modification.  275:12164-12174. 2000
  • Single repeat deletion in apoa-i blocks cholesterol esterification and results in rapid catabolism of delta 6 and wild-type apoa-i in transgenic mice.  275:12156-12163. 2000
  • Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38 alpha mitogen-activated protein kinase activity.  275:12266-12272. 2000
  • A conserved "hydrophobic staple motif" plays a crucial role in the refolding of human glutathione transferase P1-1.  275:10421-10428. 2000
  • Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK1 cells.  275:10278-10284. 2000
  • PU.1 and interferon consensus sequence-binding protein regulate the myeloid expression of the human Toll-like receptor 4 gene.  275:9773-9781. 2000
  • Active site serine promotes stabilization of the reactive glutathione thiolate in rat glutathione transferase T2-2 - Evidence against proposed sulfatase activity of the corresponding human enzyme.  275:8618-8624. 2000
  • The catalytic subunit of phosphoinositide 3-kinase: Requirements for oncogenicity.  275:6267-6275. 2000
  • A dominant-negative peroxisome proliferator-activated receptor gamma (ppar gamma) mutant is a constitutive repressor and inhibits ppar gamma-mediated adipogenesis.  275:5754-5759. 2000
  • Nuclear import adenovirus DNA in vitro involves the nuclear protein import pathway and hsc70.  275:4298-4304. 2000
  • Structure-function analysis of cd14 as a soluble receptor for lipopolysaccharide.  275:3144-3149. 2000
  • Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme. Mutations that alter aggregation, phospholipid dependence of catalysis, and membrane binding.  275:2545-2553. 2000
  • Homophilic interaction of junctional adhesion molecule.  275:30970-30976. 2000
  • Tata-binding protein and the gal4 transactivator do not bind to promoters cooperatively.  275:40797-40803. 2000
  • The retinal rod Na+/Ca2+,K+ exchanger contains a noncleaved signal sequence required for translocation of the N terminus.  274:38177-38182. 1999
  • Alteration of the reduction potential of the 4fe-4s (2+/+) cluster of azotobacter vinelandii ferredoxin i.  274:36479-36487. 1999
  • C-terminal residues 621-635 of protein S are essential for binding to factor Va.  274:36187-36192. 1999
  • Genetically encoded and post-translationally modified forms of a major histocompatibility complex class i-restricted antigen bearing a glycosylation motif are independently processed and co-presented to cytotoxic t lymphocytes.  274:36274-36280. 1999
  • Mekk3 directly regulates mek5 activity as part of the big mitogen-activated protein kinase 1 (bmk1) signaling pathway.  274:36035-36038. 1999
  • Major anticodon-binding region missing from an archaebacterial tRNA synthetase.  274:35601-35606. 1999
  • The prespore vesicles of dictyostelium discoideum - purification, characterization, and developmental regulation.  274:35823-35831. 1999
  • Expression of α2,8/2,9-polysialyltransferase from escherichia coli K92 - characterization of the enzyme and its reaction products.  274:35139-35146. 1999
  • Tropomodulin increases the critical concentration of barbed end-capped actin filaments by converting ADP.P(i)-actin to ADP-actin at all pointed filament ends.  274:34637-34645. 1999
  • The cooh terminus of aminoglycoside phosphotransferase (3 ')-iiia is critical for antibiotic recognition and resistance.  274:30697-30706. 1999
  • The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit.  274:30799-30810. 1999
  • ATP and the core "alpha-crystallin" domain of the small heat-shock protein alpha B-crystallin.  274:30190-30195. 1999
  • Beta(2)-adrenergic receptor down-regulation - evidence for a pathway that does not require endocytosis.  274:28900-28908. 1999
  • Characterization of the putative 2x 4fe-4s -binding nqo9 subunit of the proton-translocating nadh-quinone oxidoreductase (ndh-1) of paracoccus denitrificans - expression, reconstitution, and epr characterization.  274:28598-28605. 1999
  • Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor.  274:28745-28750. 1999
  • H+-translocating nadh-quinone oxidoreductase (ndh-1) of paracoccus denitrificans - studies on topology and stoichiometry of the peripheral subunits.  274:28606-28611. 1999
  • Identification of a novel tropomodulin isoform, skeletal tropomodulin, that caps actin filament pointed ends in fast skeletal muscle.  274:28466-28475. 1999
  • Interrupting the hydrogen bond network at the active site of human manganese superoxide dismutase.  274:27711-27716. 1999
  • Use of a peptide mimotope to guide the humanization of MRK-16, an anti-P-glycoprotein monoclonal antibody.  274:27371-27378. 1999
  • Tryptophan 409 controls the activity of neuronal nitric-oxide synthase by regulating nitric oxide feedback inhibition.  274:26907-26911. 1999
  • Association of neuronal calcium channels with modular adaptor proteins.  274:24453-24456. 1999
  • Macromolecular substrate affinity for the tissue factor-factor viia complex is independent of scissile bond docking.  274:24171-24175. 1999
  • Mutational analysis of the tetrahydrobiopterin-binding site in inducible nitric-oxide synthase.  274:24100-24112. 1999
  • Revisiting catalysis by chymotrypsin family serine proteases using peptide substrates and inhibitors with unnatural main chains.  274:24074-24079. 1999
  • Highly differentiated motifs responsible for two cytokine activities of a split human tRNA synthetase.  274:23155-23159. 1999
  • Nmr structure and metal interactions of the copz copper chaperone.  274:22597-22603. 1999
  • Mechanisms and consequences of affinity modulation of integrin alpha(v)beta(3) detected with a novel patch-engineered monovalent ligand.  274:21609-21616. 1999
  • Species barrier to RNA recognition overcome with nonspecific RNA binding domains.  274:16508-16512. 1999
  • A di-acidic (DxE) code directs concentration of cargo during export from the endoplasmic reticulum.  274:15937-15946. 1999
  • Molecular dissection of guanine nucleotide dissociation inhibitor function in vivo - Rab-independent binding to membranes and role of Rab recycling factors.  274:14806-14817. 1999
  • Shared and unique determinants of the erythropoietin (epo) receptor are important for binding epo and epo mimetic peptide.  274:14163-14169. 1999
  • Activation of matrix metalloproteinase-9 (mmp-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion.  274:13066-13076. 1999
  • A molecular model of alzheimer amyloid beta-peptide fibril formation.  274:12619-12625. 1999
  • Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappa B, and DNA by a designed DNA-binding ligand.  274:12765-12773. 1999
  • Identification of NSF as a beta-arrestin1-binding protein - implications for beta(2)-adrenergic receptor regulation.  274:10677-10680. 1999
  • Protein crystallization on lipid layers and structure determination of the RNA polymerase II transcription initiation complex.  274:6813-6816. 1999
  • RNA determinants for translational editing. Mischarging a minihelix substrate by a tRNA synthetase.  274:6835-6838. 1999
  • Distinct structural attributes regulating von Willebrand factor A1 domain interaction with platelet glycoprotein Ib alpha under flow.  274:6586-6593. 1999
  • Cargo can modulate COPII vesicle formation from the endoplasmic reticulum.  274:4389-4399. 1999
  • Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (hiv-1).  274:4115-4123. 1999
  • Complex formation between azotobacter vinelandii ferredoxin i and its physiological electron donor nadph-ferredoxin reductase.  274:2978-2987. 1999
  • Unique regulation of immediate early gene and tyrosine hydroxylase expression in the odor-deprived mouse olfactory bulb.  274:3042-3047. 1999
  • Definition of the sites of interaction between the protein tyrosine phosphatase SHP-1 and CD22.  274:2303-2307. 1999
  • Nf-kappa b activity is induced by neural cell adhesion molecule binding to neurons and astrocytes.  274:2432-2439. 1999
  • Antifungal imidazoles block assembly of inducible no synthase into an active dimer.  274:930-938. 1999
  • Fluid shear stress stimulates big mitogen-activated protein kinase 1 (bmk1) activity in endothelial cells - dependence on tyrosine kinases and intracellular calcium.  274:143-150. 1999
  • L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma. The role of Cys313 in ligand binding.  274:7913-7922. 1999
  • Molecular genetics of transmissible spongiform encephalopathies.  274:3-6. 1999
  • Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects.  274:6718-6725. 1999
  • The nh2-terminal region of apolipoprotein b is sufficient for lipoprotein association with glycosaminoglycans.  273:35355-35361. 1998
  • Subdomain chimeras of hepatic lipase and lipoprotein lipase - localization of heparin and cofactor binding.  273:30979-30984. 1998
  • Role of the STAT1-SH2 domain and STATE in the activation and nuclear translocation of STAT1.  273:30073-30076. 1998
  • All four homochiral enantiomers of a nuclear localization sequence derived from c-Myc serve as functional import signals.  273:29764-29769. 1998
  • Adenosine 5 '-phosphosulfate kinase from Penicillium chrysogenum - site-directed mutagenesis at putative phosphoryl-accepting and ATP P-loop residues.  273:28583-28589. 1998
  • When size is important - Accommodation of magnesium in a calcium binding regulatory domain.  273:28994-29001. 1998
  • A carboxyl-terminal extension of the zinc finger domain contributes to the specificity and polarity of peroxisome proliferator-activated receptor DNA binding.  273:27988-27997. 1998
  • Cyclic GMP and cGMP-binding phosphodiesterase are required for interleukin-1-induced nitric oxide synthesis in human articular chondrocytes.  273:27484-27491. 1998
  • Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-kappa B.  273:27467-27473. 1998
  • Newly discovered archaebacterial flap endonucleases show a structure-specific mechanism for DNA substrate binding and catalysis resembling human flap endonuclease-1.  273:27154-27161. 1998
  • Molecular role for the Rab binding platform of guanine nucleotide dissociation inhibitor in endoplasmic reticulum to Golgi transport.  273:26931-26938. 1998
  • Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes.  273:26559-26565. 1998
  • Synergistic activation of the N-methyl-D-aspartate receptor subunit 1 promoter by myocyte enhancer factor 2C and Sp1.  273:26218-26224. 1998
  • Mechanisms of spectral tuning in blue cone visual pigments. Visible and raman spectroscopy of blue-shifted rhodopsin mutants.  273:24583-24591. 1998
  • Inhibition of prothrombinase by human secretory phospholipase A2 involves binding to factor Xa.  273:23764-23772. 1998
  • Phosphorylation of the spo0b response regulator phosphotransferase of the phosphorelay initiating development in bacillus subtilis.  273:23849-23855. 1998
  • Structure of cysteine- and glycine-rich protein CRP2. Backbone dynamics reveal motional freedom and independent spatial orientation of the lim domains.  273:23233-23240. 1998
  • The catalytic site of cytochrome P4504A11 (CYP4A11) and its L131F mutant.  273:23055-23061. 1998
  • Involvement of an active-site Zn2+ ligand mechanism of human glyoxalase I.  273:21623-21628. 1998
  • Interaction between apob and hepatic lipase mediates the uptake of apob-containing lipoproteins.  273:20456-20462. 1998
  • Domain swapping in inducible nitric-oxide synthase - electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer.  273:18950-18958. 1998
  • Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria.  273:16962-16967. 1998
  • Binding site for blood coagulation factor Xa involving residues 311-325 in factor Va.  273:14900-14905. 1998
  • Cyclin d3 is rate-limiting for the g(1)/s phase transition in fibroblasts.  273:14958-14961. 1998
  • Spectinomycin kinase from legionella pneumophila - characterization of substrate specificity and identification of catalytically important residues.  273:14788-14795. 1998
  • Cloning and expression in escherichia coli of the cytochrome c(552) gene from thermus thermophilus hb8 - evidence for genetic linkage to an atp-binding cassette protein and initial characterization of the cyca gene products.  273:12006-12016. 1998
  • The hydrophobic face orientation of apolipoprotein a-i amphipathic helix domain 143-164 regulates lecithin : Cholesterol acyltransferase activation.  273:11776-11782. 1998
  • Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47(PHOX) on serine 303 or 304.  273:9539-9543. 1998
  • Mutation of the sialyltransferase s-sialylmotif alters the kinetics of the donor and acceptor substrates.  273:9608-9614. 1998
  • Binding of bacterial peptidoglycan to cd14.  273:8680-8690. 1998
  • Autoactivation of avian urokinase-type plasminogen activator (upa) - a novel mode of initiation of the upa/plasmin cascade.  273:7457-7461. 1998
  • Gene expression in scrapie - cloning a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts.  273:7691-7697. 1998
  • A second mammalian n-myristoyltransferase.  273:6595-6598. 1998
  • A minimally lipidated form of cell-derived apolipoprotein e exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteins.  273:4206-4212. 1998
  • The major nuclear envelope targeting domain of lap2 coincides with its lamin binding region but is distinct from its chromatin interaction domain.  273:4213-4219. 1998
  • Characterization of the initial alpha-thrombin interaction with glycoprotein Ib alpha in relation to platelet activation.  273:1880-1887. 1998
  • A novel calmodulin-regulated Ca2+-ATPase (ACA2) from Arabidopsis with an N-terminal autoinhibitory domain.  273:1099-1106. 1998
  • Evidence of viral capsid dynamics using limited proteolysis and mass spectrometry.  273:673-676. 1998
  • A t14c variant of azotobacter vinelandii ferredoxin i undergoes facile 3fe-4s degrees to 4fe-4s (2+) conversion in vitro but not in vivo.  273:33692-33701. 1998
  • MAGI-1, a membrane-associated guanylate kinase with a unique arrangement of protein-protein interaction domains.  272:31589-31597. 1997
  • Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38 delta.  272:30122-30128. 1997
  • CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation.  272:29207-29211. 1997
  • Major histocompatibility complex class II-dependent unfolding, transport, and degradation of endogenous proteins.  272:29127-29136. 1997
  • In vivo regulation of crkii and crkl proto-oncogenes in the uterus by insulin-like growth factor-i - differential effects on tyrosine phosphorylation and association with paxillin.  272:27660-27664. 1997
  • G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization.  272:25425-25428. 1997
  • The conserved N-capping box in the hydrophobic core of glutathione S-transferase P1-1 is essential for refolding - Identification of a buried and conserved hydrogen bond important for protein stability.  272:25518-25523. 1997
  • Characterization of UT2 cells. The induction of peroxisomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase.  272:24579-24587. 1997
  • Identification of a region in the integrin beta 3 subunit that confers ligand binding specificity.  272:23912-23920. 1997
  • Cellular binding of soluble cd14 requires lipopolysaccharide (lps) and lps-binding protein.  272:23157-23164. 1997
  • Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant.  272:22809-22816. 1997
  • Characterization of a novel iodocyanopindolol and sm-11044 binding protein, which may mediate relaxation of depolarized rat colon tonus.  272:21244-21252. 1997
  • High levels of the gtpase ran/tc4 relieve the requirement for nuclear protein transport factor 2.  272:21534-21539. 1997
  • C-src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1 (bmk1).  272:20389-20394. 1997
  • The actin cytoskeleton is required for receptor-mediated endocytosis in mammalian cells.  272:20332-20335. 1997
  • Active site modification of factor viia affects interactions of the protease domain with tissue factor.  272:19875-19879. 1997
  • Structure/function relationship of the cAMP response element in tyrosine hydroxylase gene transcription.  272:19158-19164. 1997
  • Lipopolysaccharide (lps)-binding proteins bpi and lbp form different types of complexes with lps.  272:18682-18685. 1997
  • Nmr spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2 - the carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein.  272:18038-18043. 1997
  • Ca2+ binding to the first epidermal growth factor module of coagulation factor viia is important for cofactor interaction and proteolytic function.  272:17467-17472. 1997
  • Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells - regulation by egr-1, c-jun, and nf-kappa b transcription factors.  272:17795-17801. 1997
  • Protein phosphatase 2C acts independently of stress-activated kinase cascade to regulate the stress response in fission yeast.  272:17873-17879. 1997
  • Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands.  272:17070-17077. 1997
  • Y13c azotobacter vinelandii ferredoxin i - a designed fe-s ligand motif contains a cysteine persulfide.  272:15620-15627. 1997
  • Expression and purification of the saccharomyces cerevisiae alpha-factor receptor (ste2p), a 7-transmembrane-segment g protein-coupled receptor.  272:15553-15561. 1997
  • A Rab GTPase is required for homotypic assembly of the endoplasmic reticulum.  272:13479-13483. 1997
  • Regulation of Schizosaccharomyces pombe Wee1 tyrosine kinase.  272:13320-13325. 1997
  • Solution structure of the carboxyl-terminal LIM domain from quail cysteine-rich protein CRP2.  272:12001-12007. 1997
  • pch1(+), a second essential C-type cyclin gene in Schizosaccharomyces pombe.  272:12100-12106. 1997
  • Antibody humanization using monovalent phage display.  272:10678-10684. 1997
  • Identification of a novel protein kinase A anchoring protein that binds both type l and type ll regulatory subunits.  272:8057-8064. 1997
  • Alteration in apolipoprotein a-i 22-mer repeat order results in a decrease in lecithin:Cholesterol acyltransferase reactivity.  272:7278-7284. 1997
  • HIV-1 entry and macrophage inflammatory protein-1 beta-mediated signaling are independent functions of the chemokine receptor CCR5.  272:6854-6857. 1997
  • Lipoxin A(4) stable analogs are potent mimetics that stimulate human monocytes and THP-1 cells via a G-protein-linked lipoxin A(4) receptor.  272:6972-6978. 1997
  • Human class mu glutathione transferases, in particular isoenzyme M2-2, catalyze detoxication of the dopamine metabolite aminochrome.  272:5727-5731. 1997
  • Molecular determinants of Arg-Gly-Asp ligand specificity for beta(3) integrins.  272:4103-4107. 1997
  • The proton-translocating nadh-quinone oxidoreductase (ndh-1) of thermophilic bacterium thermus thermophilus hb-8 - complete DNA sequence of the gene cluster and thermostable properties of the expressed nq02 subunit.  272:4201-4211. 1997
  • Overexpression, purification, and characterization of the catalase-peroxidase KatG from Mycobacterium tuberculosis.  272:2834-2840. 1997
  • Dissection of glutathionylspermidine synthetase/amidase from Escherichia coli into autonomously folding and functional synthetase and amidase domains.  272:2429-2436. 1997
  • Induction of interferon-gamma inducing factor in the adrenal cortex.  272:2035-2037. 1997
  • Generation of alzheimer amyloid beta peptide through nonspecific proteolysis.  272:1870-1875. 1997
  • Matrix-assisted laser desorption ionization/quadrupole ion trap mass spectrometry of peptides. Application to the localization of phosphorylation sites on the P protein from Sendai virus.  272:1735-1741. 1997
  • Tissue plasminogen activator (t-PA) is targeted to the regulated secretory pathway. Catecholamine storage vesicles as a reservoir for the rapid release of t-PA.  272:1976-1982. 1997
  • Controlling amyloid beta-peptide fibril formation with protease-stable ligands.  272:12601-12605. 1997
  • Structure-function studies of p38 mitogen-activated protein kinase - loop 12 influences substrate specificity and autophosphorylation, but not upstream kinase selection.  272:11096-11102. 1997
  • Direct association between the yeast rad51 and rad54 recombination proteins.  271:33181-33186. 1996
  • Down-regulation of beta(3) adrenoreceptor gene expression in brown fat cells is transient and recovery is dependent upon a short-lived protein factor.  271:33366-33375. 1996
  • Purification of storage granule protein-23 - a novel protein identified by phage display technology and interaction with type 1 plasminogen activator inhibitor.  271:30126-30135. 1996
  • Type 1 plasminogen activator inhibitor induces multimerization of plasma vitronectin. A suggested mechanism for the generation of the tissue form of vitronectin in vivo.  271:29644-29651. 1996
  • Rab2 is essential for the maturation of pre-Golgi intermediates.  271:29372-29379. 1996
  • Effector cell protease receptor-1 is a vascular receptor for coagulation factor xa.  271:28407-28413. 1996
  • Expression and immunoaffinity purification of human inducible nitric-oxide synthase - inhibition studies with 2-amino-5,6-dihydro-4H-1,3-thiazine.  271:28212-28219. 1996
  • Inducible cAMP early repressor can modulate tyrosine hydroxylase gene expression after stimulation of cAMP synthesis.  271:25375-25381. 1996
  • Regulation of plasminogen receptor expression on monocytoid cells by beta1-integrin-dependent cellular adherence to extracellular matrix proteins.  271:23761-23767. 1996
  • Dynamin self-assembly stimulates its gtpase activity.  271:22310-22314. 1996
  • An allosteric ca2+ binding site on the beta 3 integrins that regulates the dissociation rate for rgd ligands.  271:21745-21751. 1996
  • Molecular characterization and in vitro biological activity of placentin, a new member of the insulin gene family.  271:20238-20241. 1996
  • Binding of viral antigens to major histocompatibility complex class i h-2d(b) molecules is controlled by dominant negative elements at peptide non-anchor residues - implications for peptide selection and presentation.  271:17829-17836. 1996
  • An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones.  271:17152-17156. 1996
  • Big mitogen-activated protein kinase 1 (bmk1) is a redox-sensitive kinase.  271:16586-16590. 1996
  • Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum to Golgi transport.  271:15866-15869. 1996
  • Selection of linkers for a catalytic single-chain antibody using phage display technology.  271:15682-15686. 1996
  • A cytolytic function for a sialic acid-binding lectin that is a member of the pentraxin family of proteins.  271:14717-14721. 1996
  • Human cytoplasmic antiproteinase neutralizes rapidly and efficiently chymotrypsin and trypsin-like proteases utilizing distinct reactive site residues.  271:14526-14532. 1996
  • Structural and functional analysis of the plasminogen activator inhibitor-1 binding motif in the somatomedin B domain of vitronectin.  271:12716-12723. 1996
  • Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice.  271:9455-9459. 1996
  • Enhancement of protein kinase C-dependent O2 (bar dot) production in Epstein-Barr virus-transformed B lymphocytes by p120(Ras-GAP) antisense oligonucleotide.  271:9320-9325. 1996
  • New molecular and structural determinants involved in beta(2)-adrenergic receptor desensitization and sequestration - delineation using chimeric beta(3)/beta(2)-adrenergic receptors.  271:9355-9362. 1996
  • Arrest of beta-amyloid fibril formation by a pentapeptide ligand.  271:8545-8548. 1996
  • Conformational changes in the A1 domain of von Willebrand factor modulating the interaction with platelet glycoprotein Ibα.  271:9046-9053. 1996
  • A new function for adducin. Calcium/calmodulin-regulated capping of the barbed ends of actin filaments.  271:7986-7991. 1996
  • Molecular cloning of a developmentally regulated n-acetylgalactosamine alpha 2,6-sialyltransferase specific for sialylated glycoconjugates.  271:7450-7459. 1996
  • Identification and characterization of the cytoplasmic antiproteinase (cap) in human platelets - evidence for the interaction of cap with endogenous platelet proteins.  271:7160-7167. 1996
  • Identification of phosphorylation sites of human 85-kDa cytosolic phospholipase A(2) expressed in insect cells and present in human monocytes.  271:6987-6997. 1996
  • Differential regulation of vitronectin in mice and humans in vitro.  271:5474-5480. 1996
  • Expression and characterization of the flavoprotein subcomplex composed of 50-kda (nqo1) and 25-kda (nqo2) subunits of the proton-translocating nadh-quinone oxidoreductase of paracoccus denitrificans.  271:5907-5913. 1996
  • Role of beta 3 integrins in melanoma cell adhesion to activated platelets under flow.  271:5892-5900. 1996
  • Characterization of the structure and function of a novel map kinase kinase (mkk6).  271:2886-2891. 1996
  • Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca(2+)/calmodulin-dependent protein kinases type I, II, and IV.  271:3066-3073. 1996
  • Replacement of Trp(28) in Escherichia coli thioredoxin by site-directed mutagenesis affects thermodynamic stability but not function.  271:3091-3096. 1996
  • Genomic organization and chromosomal mapping of the gal beta 1,3galnac/gal beta 1,4glcnac alpha 2,3-sialyltransferase.  271:931-938. 1996
  • Molecular cloning, heterologous expression, and characterization of human glyoxalase II.  271:319-323. 1996
  • The high activity of rat glutathione transferase 8-8 with alkene substrates is dependent on a glycine residue in the active site.  270:29705-29709. 1995
  • Active-site and oligosaccharide recognition residues of peptide-n-4-(n-acetyl-beta-d-glucosaminyl)asparagine amidase-f.  270:29493-29497. 1995
  • Interaction of integrin alpha(IIb)beta(3) with multiple fibrinogen domains during platelet adhesion.  270:28812-28817. 1995
  • The cysteine-rich protein family of highly related LIM domain proteins.  270:28946-28954. 1995
  • Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death.  270:27932-27936. 1995
  • Molecular-cloning of bomapin (protease-inhibitor-10), a novel human serpin that is expressed specifically in the bone-marrow.  270:26754-26757. 1995
  • Rho-family gtpases regulate p38 mitogen-activated protein-kinase through the downstream mediator pak1.  270:23934-23936. 1995
  • Two mutations in the promoter region of the human protein-C gene both cause type-I protein-C deficiency by disruption of 2 HNF-3 binding-sites.  270:24216-24221. 1995
  • Characterization of the unique mechanism mediating the shear-dependent binding of soluble von Willebrand factor to platelets.  270:23352-23361. 1995
  • Cloning, sequencing, and regulation of the glutathione reductase gene from the cyanobacterium Anabaena PCC 7120.  270:22882-22889. 1995
  • Silencer elements modulate the expression of the gene for the neuron-glia cell-adhesion molecule, ng-cam.  270:21291-21298. 1995
  • Molecular-genetic and protein chemical characterization of the cytochrome ba(3) from thermus-thermophilus hb8.  270:20345-20358. 1995
  • A role for acidic residues in di-leucine motif-based targeting to the endocytic pathway.  270:19989-19997. 1995
  • Ricin cytotoxicity is sensitive to recycling between the endoplasmic-reticulum and the Golgi-complex.  270:20078-20083. 1995
  • Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase.  270:18929-18934. 1995
  • Expression and characterization of the 66-kilodalton (nqo3) iron-sulfur subunit of the proton-translocating nadh-quinone oxidoreductase of paracoccus-denitrificans.  270:18264-18270. 1995
  • The activation state of the integrin alpha(IIb)beta(3) affects outside-in signals leading to cell spreading and focal adhesion kinase phosphorylation.  270:18133-18140. 1995
  • Novel sequence determinants in peroxisome proliferator signaling.  270:16114-16121. 1995
  • Incorporation of d-alanine into lipoteichoic acid and wall teichoic-acid in bacillus-subtilis - identification of genes and regulation.  270:15598-15606. 1995
  • Platelet-activating factor induces NF-kappa B activation through a G protein-coupled pathway.  270:14928-14934. 1995
  • Alpha(2)-macroglobulin-mediated clearance of proteases from the plasma of the american horseshoe-crab, limulus-polyphemus.  270:13496-13502. 1995
  • Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta(3) subunit.  270:11947-11954. 1995
  • Analysis of the hormone-dependent regulation of a JunD-estrogen receptor chimera.  270:11502-11513. 1995
  • Lipopolysaccharide-binding protein-mediated complexation of lipopolysaccharide with soluble cd14.  270:10482-10488. 1995
  • Long-term phorbol ester treatment down-regulates the beta(3)-adrenergic receptor in 3t3-f442a adipocytes.  270:10952-10959. 1995
  • The role of Tyr13 and Lys15 of interleukin-8 in the high affinity interaction with the interleukin-8 receptor type A.  270:10428-10431. 1995
  • Identification of three tyrosine residues of glycoprotein Ib alpha with distinct roles in von Willebrand factor and alpha-thrombin binding.  270:9571-9578. 1995
  • Cdna cloning and characterization of lamina-associated polypeptide 1c (lap1c), an integral protein of the inner nuclear-membrane.  270:8822-8828. 1995
  • The retinoblastoma susceptibility gene-product represses transcription when directly bound to the promoter.  270:8837-8843. 1995
  • Lipoprotein-lipase association with lipoproteins involves protein-protein interaction with apolipoprotein-b.  270:8081-8086. 1995
  • Platelet-activating factor stimulates transcription of the heparin-binding epidermal growth factor-like growth factor in monocytes. Correlation with an increased kappa B binding activity.  270:7787-7790. 1995
  • An inactivating point mutation demonstrates that interaction of cAMP response element binding protein (CREB) with the CREB binding protein is not sufficient for transcriptional activation.  270:7041-7044. 1995
  • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine.  270:7420-7426. 1995
  • Calmodulin stabilizes an amphiphilic alpha-helix within rc3/neurogranin and gap-43/neuromodulin only when ca2+ is absent.  270:6741-6750. 1995
  • Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.  270:5872-5876. 1995
  • Homology dependence of uvsx protein-catalyzed joint molecule formation.  270:5181-5186. 1995
  • Lipopolysaccharide (lps) signal-transduction and clearance - dual roles for lps binding-protein and membrane cd14.  270:5320-5325. 1995
  • Radicicol, a protein-tyrosine kinase inhibitor, suppresses the expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide and in experimental glomerulonephritis.  270:5418-5426. 1995
  • Localization of the disulfide bond involved in post-translational processing of glycosylasparaginase and disrupted by a mutation in the Finnish-type aspartylglycosaminuria.  270:3212-3215. 1995
  • The sialyltransferase sialylmotif participates in binding the donor substrate cmp-neuac.  270:1497-1500. 1995
  • Building synthetic antibodies as adhesive ligands for integrins.  269:32788-32795. 1994
  • Species-difference in the g-protein selectivity of the human and bovine a(1)-adenosine receptor.  269:32077-32084. 1994
  • P145, a major grb2-binding protein in brain, is co-localized with dynamin in nerve-terminals where it undergoes activity-dependent dephosphorylation.  269:30132-30139. 1994
  • Triple hydroxylation of tetracenomycin-a2 to tetracenomycin-c in streptomyces-glaucescens - overexpression of the tcmg gene in streptomyces-lividans and characterization of the tetracenomycin-a2 oxygenase.  269:30726-30733. 1994
  • Human glycyl-tRNA synthetase. Wide divergence of primary structure from bacterial counterpart and species-specific aminoacylation.  269:30049-30055. 1994
  • Syntaxin-5 regulates endoplasmic-reticulum to golgi transport.  269:29363-29366. 1994
  • Low molecular weight protein-tyrosine phosphatases are highly conserved between fission yeast and man.  269:27996-27999. 1994
  • Isoform-specific interaction of tropomodulin with skeletal muscle and erythrocyte tropomyosins.  269:27510-27518. 1994
  • Export of protein from the endoplasmic-reticulum is regulated by a diacylglycerol phorbol ester binding-protein.  269:26848-26857. 1994
  • The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin.  269:26691-26696. 1994
  • Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and L6 myotubes.  269:25735-25741. 1994
  • Endothelin induces tyrosine phosphorylation and grb2 association of shc in astrocytes.  269:24805-24809. 1994
  • Alterations of the regiospecificity of progesterone metabolism by the mutagenesis of two key amino acid residues in rabbit cytochrome P450 2C3v.  269:23937-23943. 1994
  • Expression of human apolipoprotein b90 in transgenic mice - demonstration that apolipoprotein b90 laces the structural requirements to form lipoprotein(a).  269:24284-24289. 1994
  • Tubulin gtp hydrolysis influences the structure, mechanical-properties, and kinesin driven transport of microtubules.  269:23769-23775. 1994
  • Interactions of active-site residues and catalytic activity of human carbonic anhydrase III.  269:23002-23006. 1994
  • Binding and activation of the promoter for the neural cell-adhesion molecule by pax-8.  269:22245-22252. 1994
  • Mutational and biophysical studies suggest rc3/neurogranin regulates calmodulin availability.  269:22420-22426. 1994
  • Cloning, expression, and characterization of human apolipoprotein(a) kringle iv37.  269:21820-21827. 1994
  • Inhibition of calcineurin by a novel fk-506-binding protein.  269:21094-21102. 1994
  • Properties of the iron-sulfur center in the 25-kilodalton subunit of the proton-translocating nadh-quinone oxidoreductase of paracoccus-denitrificans.  269:21030-21036. 1994
  • Identification of a regulatory domain of the interleukin-6 receptor.  269:20791-20797. 1994
  • Zinc-dependent cell growth conferred by mutant tRNA synthetase.  269:20217-20220. 1994
  • Vitronectin gene expression in vivo. Evidence for extrahepatic synthesis and acute phase regulation.  269:19836-19842. 1994
  • High molecular-weight kininogen binds to mac-1 on neutrophils by its heavy-chain (domain-3) and its light-chain (domain-5).  269:19307-19312. 1994
  • Key ligand interface residues in tissue factor contribute independently to factor viia binding.  269:19399-19403. 1994
  • Synthetic compound peptide simulating antigenicity of conformation-dependent autoepitope.  269:18529-18534. 1994
  • Differential expression of 5 sialyltransferase genes in human tissues.  269:17872-17878. 1994
  • Interaction of the peroxisome proliferator-activated receptor-alpha with the retinoid-X receptor-alpha unmasks a cryptic peroxisome proliferator response element that overlaps an ARP-1-binding site in the CYP4A6 promoter.  269:18083-18089. 1994
  • Interleukin-1-beta regulates human cytotrophoblast metalloproteinase activity and invasion in-vitro.  269:17125-17131. 1994
  • Subunit composition and domain-structure of the spo0a sporulation transcription factor of bacillus-subtilis.  269:16977-16982. 1994
  • The amino-terminus of the human c5a receptor is required for high-affinity c5a binding and for receptor activation by c5a but not c5a analogs.  269:14446-14450. 1994
  • Capsid assembly in a family of animal viruses primes an autoproteolytic maturation that depends on a single aspartic acid residue.  269:13680-13684. 1994
  • Cell-specific down-regulation of the beta(3)-adrenergic receptor.  269:13148-13155. 1994
  • Cellular differences in lipoprotein lipase-mediated uptake of low-density lipoproteins.  269:13129-13135. 1994
  • Intercellular-adhesion molecule-1 activation induces tyrosine phosphorylation of the cytoskeleton-associated protein cortactin in brain microvessel endothelial-cells.  269:12536-12540. 1994
  • ntf1+ encodes a 6-cysteine zinc finger-containing transcription factor that regulates the nmt1 promoter in fission yeast.  269:11921-11926. 1994
  • Identification of a novel integrin binding-site in fibronectin - differential utilization by beta-3 integrins.  269:10856-10863. 1994
  • Localization of an apolipoprotein-a-i epitope critical for lipoprotein-mediated cholesterol efflux from monocytic cells.  269:10288-10297. 1994
  • An amino-terminal fragment of apolipoprotein-b binds to lipoprotein-lipase and may facilitate its binding to endothelial-cells.  269:9409-9412. 1994
  • Human neutrophil phagocytic granules contain a truncated soluble form of the alzheimer beta/a4 amyloid precursor protein (app).  269:9805-9810. 1994
  • Azotobacter-vinelandii ferredoxin-i - alteration of individual surface-charges and the 4fe-4s (2+/+) cluster reduction potential.  269:8564-8575. 1994
  • Lipopolysaccharide (lps) binding-protein, truncated at ile-197, binds lps but does not transfer lps to cd14.  269:8172-8175. 1994
  • Lipopolysaccharide binding protein expression in primary human hepatocytes and HepG2 hepatoma cells.  269:8477-8482. 1994
  • Identification of a p53 binding-site in the human retinoblastoma susceptibility gene promoter.  269:6383-6389. 1994
  • Localization and characterization of an alpha-thrombin-binding site on platelet glycoprotein Ib alpha.  269:6478-6484. 1994
  • Transcriptional modulation by n-butyric acid of beta-1-adrenergic, beta-2-adrenergic, and beta-3-adrenergic receptor balance in 3t3-p442a adipocytes.  269:6664-6670. 1994
  • Cloning and analysis of a constitutive heat shock (cognate) protein 70 gene inducible by L-glutamine.  269:4513-4522. 1994
  • Microfilament reorganization is associated with functional activation of alpha(m)beta(2) on monocytic cells.  269:3159-3166. 1994
  • Structure, distribution, and functional expression of the phosphofructokinase-c isozyme.  269:3348-3355. 1994
  • A protein-S binding-site on C4b-binding protein involves beta-chain residues 31-45.  269:2535-2540. 1994
  • The somatomedin B domain of vitronectin. Structural requirements for the binding and stabilization of active type 1 plasminogen activator inhibitor.  269:2659-2666. 1994
  • Zinc-free and reduced t4 gene-32 protein binds single-stranded-DNA weakly and fails to stimulate uvsx-catalyzed homologous pairing.  269:2773-2781. 1994
  • Alternative splicing of the nc1 domain of the human-alpha-3(iv) collagen gene - differential expression of messenger-rna transcripts that predict 3 protein variants with distinct carboxyl regions.  269:2342-2348. 1994
  • Sulfated blood-group lewis(a) - a superior oligosaccharide ligand for human e-selectin.  269:1595-1598. 1994
  • Cloning of a novel alpha-2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups.  269:1394-1401. 1994
  • Dominant inhibitory mutants of arf1 block endoplasmic-reticulum to golgi transport and trigger disassembly of the golgi-apparatus.  269:1437-1448. 1994
  • Active site mutants of Escherichia coli citrate synthase. Effects of mutations on catalytic and allosteric properties.  269:412-417. 1994
  • Domains of the human neutrophil N-formyl peptide receptor involved in G protein coupling. Mapping with receptor-derived peptides.  269:326-331. 1994
  • Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells.  269:760-764. 1994
  • The human retinoblastoma susceptibility gene promoter is positively autoregulated by its own product.  269:6083-6088. 1994
  • Azotobacter-vinelandii ferredoxin-i - aspartate-15 facilitates proton-transfer to the reduced 3fe-4s cluster.  268:25928-25939. 1993
  • Crystal-structures of oxidized and reduced azotobacter-vinelandii ferredoxin at ph-8 and ph-6.  268:25920-25927. 1993
  • Analysis of lipopolysaccharide-binding by cd14.  268:24818-24823. 1993
  • Endotoxin induces rapid protein-tyrosine phosphorylation in 70z/3 cells expressing cd14.  268:25009-25014. 1993
  • How do "Zn2 cys6" proteins distinguish between similar upstream activation sites? Comparison of the DNA-binding specificity of the GAL4 protein in vitro and in vivo.  268:24699-24706. 1993
  • Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells.  268:22299-22304. 1993
  • Cassette mutagenesis of a potential substrate recognition region of cytochrome P450 2C2.  268:21997-22003. 1993
  • Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases.  268:21527-21532. 1993
  • Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIa.  268:21080-21087. 1993
  • Outside and downstream of the homeobox.  268:20683-20686. 1993
  • Ligand-induced internalization of the epidermal growth-factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors.  268:19312-19320. 1993
  • Multiple domains of the N-formyl peptide receptor are required for high-affinity ligand binding. Construction and analysis of chimeric N-formyl peptide receptors.  268:18167-18175. 1993
  • Identification of residues 413-433 of plasma protein S as essential for binding to C4b-binding protein.  268:16788-16794. 1993
  • Nitric oxide synthase structure and mechanism.  268:12231-12234. 1993
  • Analysis of structure-function relationships in the platelet membrane glycoprotein Ib-binding domain of von Willebrand's factor by expression of deletion mutants.  268:12185-12192. 1993
  • Polymerase chain-reaction cloning of a developmentally-regulated member of the sialyltransferase gene family.  268:11504-11507. 1993
  • Expression of human platelet glycoprotein Ib alpha in transgenic mice.  268:8376-8382. 1993
  • The role of protein-protein interactions in the assembly of the presynaptic filament for t4 homologous recombination.  268:7904-7911. 1993
  • A single amino acid substitution confers progesterone 6 beta-hydroxylase activity to rabbit cytochrome P450 2C3.  268:6939-6944. 1993
  • Microhelix aminoacylation by a class I tRNA synthetase. Non-conserved base pairs required for specificity.  268:6069-6072. 1993
  • Cytochrome-oxidase genes from thermus-thermophilus - nucleotide-sequence of the fused gene and analysis of the deduced primary structures for subunit-i and subunit-iii of cytochrome-caa3.  268:5395-5408. 1993
  • Purification of glutamine tRNA synthetase from Saccharomyces cerevisiae. A monomeric aminoacyl-tRNA synthetase with a large and dispensable NH2-terminal domain.  268:5519-5523. 1993
  • Oligomerization of immunoglobulin-g heavy and light-chains in vitro - a cell-free assay to study the assembly of the endoplasmic-reticulum.  268:5182-5192. 1993
  • Differential inhibition of multiple vesicular transport steps between the endoplasmic-reticulum and trans-golgi network.  268:4216-4226. 1993
  • Regulation of alpha-2,3-sialyltransferase expression correlates with conversion of peanut agglutinin (pna)+ to pna- phenotype in developing thymocytes.  268:3801-3804. 1993
  • Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C.  268:2872-2877. 1993
  • Disulfide bond requirements for assembly of the platelet glycoprotein Ib-binding domain of von Willebrand factor.  268:2821-2827. 1993
  • Role of the membrane-surface in the activation of human coagulation factor-x.  267:26110-26120. 1992
  • Tripartite functional assembly of a large class I aminoacyl tRNA synthetase.  267:22703-22706. 1992
  • Tissue factor residues 157-167 are required for efficient proteolytic activation of factor-x and factor-vii.  267:22206-22210. 1992
  • Cloning and expression of the gal-beta-1,3galnac alpha-2,3-sialyltransferase.  267:21004-21010. 1992
  • Primary structure of gal-beta-1,3(4)glcnac alpha-2,3-sialyltransferase determined by mass-spectrometry sequence-analysis and molecular-cloning - evidence for a protein motif in the sialyltransferase gene family.  267:21011-21019. 1992
  • Absence of G(i) proteins in the Sf9 insect cell. Characterization of the uncoupled recombinant N-formyl peptide receptor.  267:19757-19760. 1992
  • Assembly and expression of an intrinsic factor-IX activator complex on the surface of cultured human endothelial-cells.  267:19833-19839. 1992
  • The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome-P450 fatty-acid omega-hydroxylase, by clofibric acid.  267:19051-19053. 1992
  • A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3.  267:18085-18092. 1992
  • Interaction of xenopus TFIIIC with the TFIIIA.5-S RNA gene-complex.  267:18190-18198. 1992
  • Transactivation of the c-myc promoter by human t-cell leukemia-virus type-1 tax is mediated by nf-kappa-b.  267:16288-16291. 1992
  • Characterization and nucleotide binding-properties of a mutant dihydropteridine reductase containing an aspartate 37-isoleucine replacement.  267:15334-15339. 1992
  • Function independence of microhelix aminoacylation from anticodon binding in a class I tRNA synthetase.  267:15563-15567. 1992
  • Inhibition by dexamethasone of beta-3-adrenergic receptor responsiveness in 3t3-f442a adipocytes - evidence for a transcriptional mechanism.  267:15909-15915. 1992
  • A synthetic sialic-acid analog is recognized by influenza-c virus as a receptor determinant but is resistant to the receptor-destroying enzyme.  267:12501-12505. 1992
  • Adp-ribosylation factor is required for vesicular trafficking between the endoplasmic-reticulum and the cis-golgi compartment.  267:13053-13061. 1992
  • Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor.  267:11300-11306. 1992
  • Functional expression of the human serotonin 5-ht1a receptor in escherichia-coli - ligand-binding properties and interaction with recombinant g-protein alpha-subunits.  267:8200-8206. 1992
  • The signal anchor and stem regions of the beta-galactoside alpha-2,6-sialyltransferase may each act to localize the enzyme to the golgi-apparatus.  267:7784-7793. 1992
  • Cofactor residues lysine-165 and lysine-166 are critical for protein substrate recognition by the tissue factor-factor-viia protease complex.  267:6375-6381. 1992
  • Distinct biological consequences of integrin alpha v beta 3-mediated melanoma cell adhesion to fibrinogen and its plasmic fragments.  267:5070-5077. 1992
  • Induction of cyclin messenger-rna and cyclin-associated histone-h1 kinase during liver-regeneration.  267:2841-2844. 1992
  • Regulated expression of alpha-2,6-sialyltransferase by the liver-enriched transcription factors hnf-1, dbp, and lap.  267:3466-3472. 1992
  • Anti-idiotypic antibodies against an antibody to the platelet glycoprotein (GP) IIb-IIIa complex mimic GP IIb-IIIa by recognizing fibrinogen.  267:2775-2785. 1992
  • Molecular cloning and characterization of human fetal liver tropomodulin. A tropomyosin-binding protein.  267:2616-2621. 1992
  • Tissue-specific alternative splicing of the beta-galactoside alpha-2,6-sialyltransferase gene.  267:2512-2518. 1992
  • Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.  267:546-554. 1992
  • Identification of a sequence of human activated protein-C (residues 390-404) essential for its anticoagulant activity.  266:24514-24519. 1991
  • Function of glycoprotein Ib alpha in platelet activation induced by alpha-thrombin.  266:23776-23783. 1991
  • Localization of an apolipoprotein-a-i epitope critical for activation of lecithin-cholesterol acyltransferase.  266:23886-23892. 1991
  • A synthetic peptide mimic of plasma apolipoprotein-e that binds the ldl receptor.  266:22803-22806. 1991
  • Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor beta.  266:23048-23052. 1991
  • Purification of the inducible murine macrophage nitric oxide synthase. Identification as a flavoprotein.  266:22789-22791. 1991
  • Crystallographic analysis of 2 site-directed mutants of azotobacter-vinelandii ferredoxin.  266:21558-21562. 1991
  • The role of cysteine 206 in allosteric inhibition of Escherichia coli citrate synthase. Studies by chemical modification, site-directed mutagenesis, and 19-F NMR.  266:20709-20713. 1991
  • Atypical beta-adrenergic-receptor in 3t3-f442a adipocytes pharmacological and molecular relationship with the human beta-3-adrenergic receptor.  266:20329-20336. 1991
  • Reaction of proteinases with alpha-2-macroglobulin from the american horseshoe-crab, limulus.  266:19426-19431. 1991
  • Identification of divalent metal ion-dependent inhibition of activated protein-C by alpha-2-macroglobulin and alpha-2-antiplasmin in blood and comparisons to inhibition of factor-Xa, thrombin, and plasmin.  266:17606-17612. 1991
  • Structural relationships and the classification of aminoacyl-tRNA synthetases.  266:16965-16968. 1991
  • Tandem mass-spectrometry identifies sites of 3 posttranslational modifications of spinach light-harvesting chlorophyll protein-II - proteolytic cleavage, acetylation, and phosphorylation.  266:17584-17591. 1991
  • Contacts between 5S DNA and Xenopus TFIIIA identified using 5-azido-2'-deoxyuridine-substituted DNA.  266:16478-16484. 1991
  • Characterization of factor-vii association with tissue factor in solution - high and low affinity calcium-binding sites in factor-vii contribute to functionally distinct interactions.  266:15719-15725. 1991
  • Only multimers of a synthetic peptide of human apolipoprotein-e are biologically-active.  266:15009-15015. 1991
  • Electrostatic orientation of the electron-transfer complex between plastocyanin and cytochrome c.  266:13431-13441. 1991
  • SPARC induces the expression of type 1 plasminogen activator inhibitor in cultured bovine aortic endothelial cells.  266:13178-13184. 1991
  • Sequential transport of protein between the endoplasmic-reticulum and successive golgi compartments in semi-intact cells.  266:13055-13063. 1991
  • The transition-state regulator hpr of bacillus-subtilis is a DNA-binding protein.  266:13411-13417. 1991
  • Independent assembly and secretion of a dimeric adhesive domain of von Willebrand factor containing the glycoprotein Ib-binding site.  266:12342-12347. 1991
  • Urinary protein-C inhibitor - glycosaminoglycans synthesized by the epithelial kidney-cell line TCL-598 enhance its interaction with urokinase.  266:11851-11857. 1991
  • Yeast expression of a catalytic antibody with chorismate mutase activity.  266:11901-11908. 1991
  • Selective recognition of adhesive sites in surface-bound fibrinogen by glycoprotein IIb-IIIa on nonactivated platelets.  266:11227-11233. 1991
  • The integrity of the cysteine-186-cysteine-209 bond of the 2nd disulfide loop of tissue factor is required for binding of factor-vii.  266:10294-10299. 1991
  • Inhibition of protein-mediated homologous pairing by a DNA helicase.  266:9712-9718. 1991
  • A 28,000-Da GDP/GTP-binding protein specific to the nuclear envelope.  266:7602-7608. 1991
  • An inhibitory monoclonal antibody binds in close proximity to a determinant for substrate binding in cytochrome P450IIC5.  266:6215-6220. 1991
  • Glycosaparaginase from human leukocytes. Inactivation and covalent modification with diazo-oxonorvaline.  266:5860-5869. 1991
  • Mapping apolipoprotein-b on the low-density-lipoprotein surface by immunoelectron microscopy.  266:5955-5962. 1991
  • Cytochrome-oxidase genes from thermus-thermophilus - nucleotide-sequence and analysis of the deduced primary structure of subunit-iic of cytochrome-caa3.  266:5025-5035. 1991
  • Isolation and characterization of a 70-kda metalloprotease (gelatinase) that is elevated in rous-sarcoma virus-transformed chicken-embryo fibroblasts.  266:5113-5121. 1991
  • Aminoacylation of alanine minihelices. "Discriminator" base modulates transition state of single turnover reaction.  266:2705-2708. 1991
  • C-13 NMR evidence that substitution of glutamine for arginine-3500 in familial defective apolipoprotein-b-100 disrupts the conformation of the receptor-binding domain.  266:2701-2704. 1991
  • Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin.  266:2824-2830. 1991
  • Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA).  266:2017-2020. 1991
  • Phospholipid-independent and phospholipid-dependent interactions required for tissue factor receptor and cofactor function.  266:2158-2166. 1991
  • Structure of alpha-2-macroglobulin from the arthropod limulus-polyphemus.  266:2526-2530. 1991
  • Use of in vitro protein-synthesis from polymerase chain reaction-generated templates to study interaction of Escherichia-coli transcription factors with core RNA-polymerase and for epitope mapping of monoclonal-antibodies.  266:2632-2638. 1991
  • Resonance raman and electron-paramagnetic resonance structural investigations of neutrophil cytochrome-b558.  266:1627-1634. 1991
  • Identification of discontinuous von Willebrand factor sequences involved in complex formation with botrocetin. A model for the regulation of von Willebrand factor binding to platelet glycoprotein Ib.  266:18172-18178. 1991
  • Site-directed mutagenesis of a soluble recombinant fragment of platelet glycoprotein Ib alpha demonstrating negatively charged residues involved in von Willebrand factor binding.  266:15474-15480. 1991
  • Protein-structure determination in solution by NMR-spectroscopy.  265:22059-22062. 1990
  • Organization of the beta-galactoside alpha-2,6-sialyltransferase gene - evidence for the transcriptional regulation of terminal glycosylation.  265:20863-20868. 1990
  • The role of the bacteriophage-t4 gene-32 protein in homologous pairing.  265:20966-20969. 1990
  • Sequential intermediates in the transport of protein between the endoplasmic-reticulum and the golgi.  265:18298-18310. 1990
  • Differential regulation of beta-1-adrenergic and beta-2-adrenergic receptor protein and messenger-rna levels by glucocorticoids during 3t3-f442a adipose differentiation.  265:16343-16349. 1990
  • Changes in crystallographic structure and thermostability of a Cu,Zn superoxide-dismutase mutant resulting from the removal of a buried cysteine.  265:14234-14241. 1990
  • Characterization of the CYP2C5 gene in 21L III/J rabbits. Allelic variation affects the expression of P450IIC5.  265:14662-14668. 1990
  • Molecular cloning of protein phosphatase inhibitor-1 and its expression in rat and rabbit tissues.  265:13415-13418. 1990
  • A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin mac-1 (cd11b cd18).  265:12119-12122. 1990
  • Cloning, sequencing, and expression of the genes encoding the adenosylcobalamin-dependent ethanolamine ammonia-lyase of salmonella-typhimurium.  265:12462-12466. 1990
  • Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sites.  265:12267-12271. 1990
  • Regulation of the hepatic synthesis of C1 inhibitor by the hepatocyte stimulating factors interleukin-6 and interferon-gamma.  265:12664-12670. 1990
  • Binding of the snake venom-derived proteins applaggin and echistatin to the arginine-glycine-aspartic acid recognition site(s) on platelet glycoprotein IIb.IIIa complex inhibits receptor function.  265:11766-11772. 1990
  • Metabolism-based covalent bonding of the heme prosthetic group to its apoprotein during the reductive debromination of BrCCl3 by myoglobin.  265:10340-10346. 1990
  • Identification of lipopolysaccharide-binding proteins in 70z/3 cells by photoaffinity cross-linking.  265:9520-9525. 1990
  • Transport and secretion of truncated t-cell receptor beta-chain occurs in the absence of association with cd3.  265:9296-9301. 1990
  • Crystallization and characterization of Chromatium vinosum cytochrome c'.  265:5364-5365. 1990
  • Diffraction quality crystals of lysin from spermatozoa of the red abalone (haliotis-rufescens).  265:4958-4961. 1990
  • A single-stranded nucleic-acid binding sequence common to the heterogeneous nuclear ribonucleoparticle protein-a1 and murine recombinant virus gp70.  265:3674-3678. 1990
  • Highly sulfated glycosaminoglycans augment the cross-linking of vitronectin by guinea pig liver transglutaminase. Functional studies of the cross-linked vitronectin multimers.  265:3543-3548. 1990
  • Biochemical purification and crystallographic characterization of the fiber-forming protein pilin from Neisseria-gonorrhoeae.  265:2278-2285. 1990
  • Inhibition of activated protein C by recombinant alpha 1-antitrypsin variants with substitution of arginine or leucine for methionine-358.  265:2365-2369. 1990
  • Studies on the nadh-menaquinone oxidoreductase segment of the respiratory-chain in thermus-thermophilus hb-8.  265:1360-1368. 1990
  • A mutation in the small (alpha) subunit of glycyl-tRNA synthetase affects amino acid activation and subunit association parameters.  265:1005-1009. 1990
  • Deletions in the large (beta) subunit of a hetero-oligomeric aminoacyl-tRNA synthetase.  265:1000-1004. 1990
  • Identification of a site in the alpha chain of platelet glycoprotein Ib that participates in von Willebrand factor binding.  265:274-280. 1990
  • Lipopolysaccharide induces hyporesponsiveness to its own action in raw 2647 cells.  264:21951-21956. 1989
  • Hydrodynamic, electron-microscopic, and ligand-binding analysis of the epstein-barr virus c3dg receptor (cr-2).  264:20576-20582. 1989
  • Macrophage oxidation of l-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor.  264:19654-19658. 1989
  • The amino-acid sequence of the sex steroid-binding protein of rabbit serum.  264:19066-19075. 1989
  • Conversion of a golgi-apparatus sialyltransferase to a secretory protein by replacement of the nh2-terminal signal anchor with a signal peptide.  264:17619-17622. 1989
  • Glycosyltransferases - structure, localization, and control of cell type-specific glycosylation.  264:17615-17618. 1989
  • Biochemistry of interorganelle transport - a new frontier in enzymology emerges from versatile in vitro model systems.  264:16965-16968. 1989
  • The phage-t4 uvsy recombination protein stabilizes presynaptic filaments.  264:16451-16457. 1989
  • Alternative cleavage of the cachectin tumor necrosis factor propeptide results in a larger, inactive form of secreted protein.  264:16256-16260. 1989
  • Regulation of the rabbit cytochrome-P-450 3C gene - age-dependent expression and transcriptional activation by rifampicin.  264:16222-16228. 1989
  • Preliminary crystallographic data and primary sequence for anti-peptide fab' b13i2 and its complex with the c-helix peptide from myohemerythrin.  264:15721-15725. 1989
  • Alteration of terminal glycosylation sequences on n-linked oligosaccharides of chinese-hamster ovary cells by expression of beta-galactoside alpha-2,6-sialyltransferase.  264:13848-13855. 1989
  • Crystallization and preliminary-x-ray diffraction studies of a complex between interleukin-2 and a soluble form of the p55 component of the high-affinity interleukin-2 receptor.  264:12730-12736. 1989
  • Interaction of type 1 plasminogen activator inhibitor with the enzymes of the contact activation system.  264:11738-11743. 1989
  • Tissue-specific expression of sialyltransferases.  264:10931-10934. 1989
  • Identification of a lipid-a binding-site in the acute phase reactant lipopolysaccharide binding-protein.  264:10867-10871. 1989
  • Regulation of type 1 plasminogen activator inhibitor gene expression in cultured bovine aortic endothelial cells. Induction by transforming growth factor-beta, lipopolysaccharide, and tumor necrosis factor-alpha.  264:10396-10401. 1989
  • 4-O-acetyl-N-acetylneuraminic acid in the N-linked carbohydrate structures of equine and guinea pig alpha 2-macroglobulins, potent inhibitors of influenza virus infection.  264:9842-9849. 1989
  • Basis for the potent inhibition of influenza-virus infection by equine and guinea-pig alpha-2-macroglobulin.  264:9850-9858. 1989
  • Preliminary crystallographic investigations of glycinamide ribonucleotide transformylase.  264:9703-9706. 1989
  • Inhibition studies on the membrane-associated phospholipase A2 in vitro and prostaglandin E2 production in vivo of the macrophage-like P388D1 cell. Effects of manoalide, 7,7-dimethyl-5,8-eicosadienoic acid, and p-bromophenacyl bromide.  264:8520-8528. 1989
  • Several gtp-binding proteins, including p21c-h-ras, are preferred substrates of pseudomonas-aeruginosa exoenzyme-s.  264:9004-9008. 1989
  • Chemical modification of bovine pancreatic trypsin inhibitor for single site coupling of immunogenic peptides for NMR conformational analysis.  264:7882-7888. 1989
  • Binding of type 1 plasminogen activator inhibitor to the extracellular matrix of cultured bovine endothelial cells.  264:5058-5063. 1989
  • Genetically engineered polymers of human Cu Zn superoxide-dismutase - biochemistry and serum half-lives.  264:5260-5268. 1989
  • Introduction of a metal-dependent regulatory switch into an enzyme.  264:3666-3669. 1989
  • Phosphofructokinase isozyme expression during myoblast differentiation.  264:3658-3661. 1989
  • An infrared study of the binding and photodissociation of carbon-monoxide in cytochrome-ba3 from thermus-thermophilus.  264:2405-2408. 1989
  • Sequential receptor cascade for coagulation proteins on monocytes - constitutive biosynthesis and functional prothrombinase activity of a membrane form of factor v-va.  264:2969-2972. 1989
  • Post-translational addition of chondroitin sulfate glycosaminoglycans - role of n-linked oligosaccharide addition, trimming, and processing.  264:1779-1786. 1989
  • Purification of a protein from bovine plasma that binds to type 1 plasminogen activator inhibitor and prevents its interaction with extracellular matrix. Evidence that the protein is vitronectin.  264:936-939. 1989
  • Amino acid sequence analysis of two mouse calbindin-D9k isoforms by tandem mass spectrometry. Protein modification by internal insertion of a single amino acid.  264:6580-6586. 1989
  • In vitro use of monoclonal-antibodies in Escherichia-coli S-30 extracts to determine the RNA-polymerase sigma-subunit required by a promoter.  264:3794-3798. 1989
  • Isolation of the von Willebrand factor domain interacting with platelet glycoprotein Ib, heparin, and collagen and characterization of its three distinct functional sites.  264:17361-17367. 1989
  • Rationale for engineering an enzyme by introducing a mutation that compensates for a deletion.  263:18598-18600. 1988
  • Isolation and functional characterization of the von Willebrand factor-binding domain located between residues His1-Arg293 of the alpha-chain of glycoprotein Ib.  263:18473-18479. 1988
  • Structure of the von Willebrand factor domain interacting with glycoprotein Ib.  263:17901-17904. 1988
  • Positive effectors of the binding of an active site-directed amino steroid to rabbit cytochrome-P-450-3C.  263:17672-17677. 1988
  • Evidence for interaction of an aminoacyl transfer RNA synthetase with a region important for the identity of its cognate transfer RNA.  263:16527-16530. 1988
  • Preliminary crystallographic data, primary sequence, and binding data for an anti-peptide fab and its complex with a synthetic peptide from influenza-virus hemagglutinin.  263:17100-17105. 1988
  • Identification of the dicyclohexylcarbodiimide-binding subunit of nadh-ubiquinone oxidoreductase (complex-i).  263:16150-16155. 1988
  • A family of lipopolysaccharide binding-proteins involved in responses to gram-negative sepsis.  263:13479-13481. 1988
  • Localization of 2 epitopes of apolipoprotein-a-i that are exposed on human high-density lipoproteins using monoclonal-antibodies and synthetic peptides.  263:13779-13785. 1988
  • Crystallization of trimeric recombinant human-tumor necrosis factor (cachectin).  263:12816-12819. 1988
  • A human-brain glycoprotein related to the mouse-cell adhesion molecule l1.  263:11943-11947. 1988
  • Crystallization and preliminary-x-ray diffraction studies of a toxic crystal protein from a subspecies of bacillus-thuringiensis.  263:11800-11801. 1988
  • Liver (b-type) phosphofructokinase messenger-rna - cloning, structure, and expression.  263:11755-11759. 1988
  • Physiologic inhibition of human activated protein-C by alpha-1-antitrypsin.  263:11613-11616. 1988
  • The cell-binding domains of plasminogen and their function in plasma.  263:11928-11934. 1988
  • Apoprotein-e-rich high-density lipoproteins inhibit ovarian androgen synthesis.  263:10965-10973. 1988
  • 7-iron ferredoxin revisited.  263:9256-9260. 1988
  • The mechanism of homologous DNA strand exchange catalyzed by the bacteriophage-t4 uvsx and gene-32 proteins.  263:9427-9436. 1988
  • Generation and characterization of peptide-specific antibodies that inhibit von Willebrand factor binding to glycoprotein IIb-IIIa without interacting with other adhesive molecules. Selectivity is conferred by Pro1743 and other amino acid residues adjacent to the sequence Arg1744-Gly1745-Asp1746.  263:7500-7505. 1988
  • Kinetic-analysis of the ca-2+-dependent, membrane-bound, macrophage phospholipase-a2 and the effects of arachidonic-acid.  263:7506-7513. 1988
  • The saturable high-affinity association of factor-x to adp-stimulated monocytes defines a novel function of the mac-1 receptor.  263:7007-7015. 1988
  • Post-golgi apparatus localization and regional expression of rat intestinal sialyltransferase detected by immunoelectron microscopy with polypeptide epitope-purified antibody.  263:6302-6309. 1988
  • Characterization of 2 crystal forms of human defensin neutrophil cationic peptide-1, a naturally-occurring antimicrobial peptide of leukocytes.  263:5933-5935. 1988
  • Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor.  263:5797-5803. 1988
  • Kinetic and immunochemical studies of a receptor-like protein that binds aromatic hydrocarbons.  263:5825-5832. 1988
  • Lpr t-cell hyporesponsiveness to mitogens linked to deficient receptor-stimulated phosphoinositide hydrolysis.  263:3626-3631. 1988
  • Novel subunit structure observed for noncooperative hemoglobin from urechis-caupo.  263:3462-3465. 1988
  • Solubilization, purification, and characterization of a membrane-bound phospholipase-a2 from the p388d1 macrophage-like cell-line.  263:3079-3085. 1988
  • The primary structure of the mitochondrial energy-linked nicotinamide nucleotide transhydrogenase deduced from the sequence of cdna clones.  263:2761-2767. 1988
  • Isolation of a functional human gene for brain creatine kinase.  263:2442-2446. 1988
  • Human-melanoma antigen o-acetylated ganglioside-gd3 is recognized by cancer-antennarius lectin.  263:2079-2086. 1988
  • Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.  263:1665-1675. 1988
  • Iron superoxide-dismutase - nucleotide-sequence of the gene from escherichia-coli-k12 and correlations with crystal-structures.  263:1555-1562. 1988
  • Biochemical-characterization of a sulfated phosphoglycoprotein antigen expressed on human small cell lung-carcinoma.  263:806-811. 1988
  • Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells.  263:3111-3115. 1988
  • Primary structure of beta-galactoside alpha-2,6-sialyltransferase - conversion of membrane-bound enzyme to soluble forms by cleavage of the nh2-terminal signal anchor.  262:17735-17743. 1987
  • Differential transcription of Xenopus oocyte and somatic-type 5 S genes in a Xenopus oocyte extract.  262:17100-17110. 1987
  • Evidence for structural heterogeneities and a study of exchange coupling - mossbauer studies of cytochrome c1aa3 from thermus-thermophilus.  262:16328-16332. 1987
  • Lipoprotein b37, a naturally-occurring lipoprotein containing the amino-terminal portion of apolipoprotein b100, does not bind to the apolipoprotein b,e(low density lipoprotein) receptor.  262:16604-16611. 1987
  • Structural studies and isolation of cdna clones providing the complete sequence of rat-liver dihydropteridine reductase.  262:16412-16416. 1987
  • Immunological identity of heparin-dependent plasma and urinary protein C inhibitor and plasminogen activator inhibitor-3.  262:15813-15816. 1987
  • Isolation and characterization of two domains of human von Willebrand factor that interact with fibrillar collagen types I and III.  262:13835-13841. 1987
  • Identification and purification of a novel Mr 43,000 tropomyosin-binding protein from human erythrocyte membranes.  262:12792-12800. 1987
  • Site-directed chemical modification of horse cytochrome c results in changes in antigenicity due to local and long-range conformational perturbations.  262:11591-11597. 1987
  • Autoactivation of human-plasma prekallikrein.  262:11308-11314. 1987
  • Initiation of the extrinsic pathway of coagulation - association of factor-viia with a cell-line expressing tissue factor.  262:9503-9508. 1987
  • Two nuclear factors compete for the skeletal muscle actin promoter.  262:9429-9432. 1987
  • Electron-paramagnetic-res characterization of the iron-sulfur clusters in the nadh - ubiquinone oxidoreductase segment of the respiratory-chain in paracoccus-denitrificans.  262:9147-9153. 1987
  • Proliferating cell nuclear antigen/cyclin is an interleukin 2-responsive gene.  262:8447-8450. 1987
  • Characterization of a second gene product related to rabbit cytochrome P-450 1.  262:5918-5923. 1987
  • Studies of the role of the escherichia-coli heat-shock regulatory protein sigma-32 by the use of monoclonal-antibodies.  262:5404-5407. 1987
  • A heparin-binding domain of human von Willebrand factor. Characterization and localization to a tryptic fragment extending from amino acid residue Val-449 to Lys-728.  262:1734-1739. 1987
  • Identification of the 37-kda protein displaying a variable interaction with the erythroid cell-membrane as glyceraldehyde-3-phosphate dehydrogenase.  262:649-653. 1987
  • The atpase core of a clathrin uncoating protein.  262:746-751. 1987
  • Construction and analysis of deletions in the amino-terminal extension of glutamine tRNA synthetase of Saccharomyces cerevisiae.  262:10807-10813. 1987
  • Gene for yeast glutamine tRNA synthetase encodes a large amino-terminal extension and provides a strong confirmation of the signature sequence for a group of the aminoacyl-tRNA synthetases.  262:10801-10806. 1987
  • Lipoxin-a - stereochemistry and biosynthesis.  261:6340-6345. 1986
  • Crystallographic characterization of recombinant human CuZn superoxide-dismutase.  261:6215-6218. 1986
  • A sulfhydryl presumed essential is not required for catalysis by an aminoacyl-tRNA synthetase.  261:15474-15479. 1986
  • Apolipoprotein-b mediates the capacity of low-density-lipoprotein to suppress neutrophil stimulation by particulates.  261:5662-5667. 1986
  • Isolation and characterization of a collagen binding domain in human von Willebrand factor.  261:15310-15315. 1986
  • Atp-coupled transport of vesicular stomatitis virus-g protein - functional boundaries of secretory compartments.  261:4690-4696. 1986
  • Atp-coupled transport of vesicular stomatitis virus-g protein between the endoplasmic-reticulum and the golgi.  261:4681-4689. 1986
  • Differential subcompartmentation of terminal glycosylation in the golgi-apparatus of intestinal absorptive and goblet cells.  261:14307-14312. 1986
  • Crystallographic characterization of a photoactive yellow protein with photochemistry similar to sensory rhodopsin.  261:3850-3851. 1986
  • Steady-state kinetic-studies of superoxide dismutases - saturative behavior of the copper-containing and zinc-containing protein.  261:3000-3005. 1986
  • The von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Characterization by monoclonal antibodies and partial amino acid sequence analysis of proteolytic fragments.  261:2579-2585. 1986
  • Active site-directed inhibition of rabbit cytochrome P-450 1 by amino-substituted steroids.  261:10204-10209. 1986
  • Characterization of a unique glycoprotein antigen expressed on the surface of human neuroblastoma-cells.  261:299-305. 1986
  • Interaction of S-protein of complement with thrombin and antithrombin-III during coagulation - protection of thrombin by S-protein from antithrombin-III inactivation.  261:7387-7392. 1986
  • Internal structural features of E. coli glycyl-tRNA synthetase examined by subunit polypeptide chain fusions.  261:6643-6646. 1986
  • Influenza-c virus uses 9-o-acetyl-n-acetylneuraminic acid as a high-affinity receptor determinant for attachment to cells.  261:5947-5951. 1986
  • A bacterial and silkworm aminoacyl-tRNA synthetase have a common epitope which maps to the catalytic domain of each.  261:5241-5244. 1986
  • Inhibition of post-translational modification and surface expression of a melanoma-associated chondroitin sulfate proteoglycan by diethylcarbamazine or ammonium chloride.  261:5121-5129. 1986
  • Rat Sertoli cells secrete a growth factor that blocks epidermal growth factor (EGF) binding to its receptor.  261:4076-4080. 1986
  • Ammonium-chloride interferes with a distinct step in the biosynthesis and cell-surface expression of human melanoma-type chondroitin sulfate proteoglycan.  261:3600-3606. 1986
  • Assignment of methylene proton resonances in NMR-spectra of embryonic and transformed-cells to plasma-membrane triglyceride.  261:3048-3053. 1986
  • Parallel expression of the mb19 genetic-polymorphism in apoprotein b-100 and apoprotein b-48 - evidence that both apoproteins are products of the same gene.  261:2995-2998. 1986
  • Evidence for a redox-linked ionizable group associated with the 2fe-2s cluster of thermus rieske protein.  261:2768-2771. 1986
  • A novel prefusion complex formed during protein-transport between golgi cisternae in a cell-free system.  261:2202-2207. 1986
  • Physicochemical properties of the N-formyl peptide receptor on human neutrophils.  261:1854-1857. 1986
  • Reduction of 2,4,6-trinitrobenzenesulfonate by glutathione reductase and the effect of NADP+ on the electron transfer.  261:1629-1635. 1986
  • Steady-state and transient-state kinetic-studies on the oxidation of 3,4-dimethoxybenzyl alcohol catalyzed by the ligninase of phanerocheate-chrysosporium burds.  261:1687-1693. 1986
  • Simple inhibition studies for distinction between homodimeric and heterodimeric isoenzymes of glutathione transferase.  261:1048-1051. 1986
  • Receptor interconversion model of hormone action. I. ATP-mediated conversion of estrogen receptors from a high to lower affinity state and its relationship to antiestrogen action.  261:7011-7017. 1986
  • Receptor interconversion model of hormone action. II. Nucleotide-mediated conversion of estrogen receptors from nonsteroid binding to the lower affinity binding state.  261:7018-7025. 1986
  • von Willebrand factor. A reduced and alkylated 52/48-kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein Ib.  261:381-385. 1986
  • A DNA primase from yeast - purification and partial characterization.  260:4995-5002. 1985
  • A detergent-activated tyrosinase from xenopus-laevis .1. Purification and partial characterization.  260:2535-2541. 1985
  • A detergent-activated tyrosinase from xenopus-laevis .2. Detergent activation and binding.  260:2542-2546. 1985
  • A homolog of alpha-2-macroglobulin purified from the hemolymph of the horseshoe-crab limulus-polyphemus.  260:2715-2719. 1985
  • Atp catalyzes the sequestration of clathrin during enzymatic uncoating.  260:57-62. 1985
  • Binding and activation of plasminogen on the platelet surface.  260:4303-4311. 1985
  • Endothelial cells produce a latent inhibitor of plasminogen activators that can be activated by denaturants.  260:11581-11587. 1985
  • Enzymatic dissociation of clathrin cages in a 2-stage process.  260:44-49. 1985
  • Evidence for n coordination to fe in the 2fe-2s clusters of thermus rieske protein and phthalate dioxygenase from pseudomonas.  260:3251-3254. 1985
  • Host-mediated selection of influenza-virus receptor variants - sialic acid alpha-2,6gal-specific clones of a/duck/ukraine/1/63 revert to sialic acid-alpha-2,3gal-specific wild-type inovo.  260:7362-7367. 1985
  • Immunochemical heterogeneity of human-plasma high-density lipoproteins - identification with apolipoprotein a-i-specific and a-ii-specific monoclonal-antibodies.  260:2982-2993. 1985
  • Iron-sulfur cluster in aconitase - crystallographic evidence for a 3-iron center.  260:2328-2333. 1985
  • Mechanism of androgen-receptor augmentation. Analysis of receptor synthesis and degradation by the density-shift technique.  260:455-461. 1985
  • Mechanism of the glucocorticoid regulation of growth of the androgen-sensitive prostate-derived R3327H-G8-A1 tumor cell line.  260:2454-2463. 1985
  • Multiple gene-like sequences related to the rabbit hepatic progesterone 21-hydroxylase cytochrome P-450 1.  260:3347-3354. 1985
  • Phosphorylation of the nuclear lamins during interphase and mitosis.  260:624-632. 1985
  • Primary structure of histidine-tRNA synthetase and characterization of hisS transcripts.  260:10063-10068. 1985
  • Protein-protein interactions in contact activation of blood-coagulation - binding of high molecular-weight kininogen and the 5-(iodoacetamido)fluorescein-labeled kininogen light chain to prekallikrein, kallikrein, and the separated kallikrein heavy and light-chains.  260:2434-2443. 1985
  • Purification and characterization of an o-acetylsialic acid-specific lectin from a marine crab cancer-antennarius.  260:8850-8856. 1985
  • Purification and partial characterization of a nucleolar scleroderma antigen (Mr = 34,000; pI, 8.5) rich in NG,NG-dimethylarginine.  260:14304-14310. 1985
  • Regulation of the oxidative response of human granulocytes to chemoattractants. No evidence for stimulated traffic of redox enzymes between endo and plasma membranes.  260:6541-6547. 1985
  • Sialylation of glycoprotein oligosaccharides with n-acetylneuraminic, n-glycolylneuraminic, and n-o-diacetylneuraminic acids.  260:8838-8849. 1985
  • Signal transduction and ligand-receptor dynamics in the human neutrophil. Transient responses and occupancy-response relations at the formyl peptide receptor.  260:1461-1467. 1985
  • Stoichiometric binding of apolipoprotein b-specific monoclonal-antibodies to low-density lipoproteins.  260:956-960. 1985
  • The complete amino acid sequence of a constitutive form of liver microsomal cytochrome P-450.  260:5427-5434. 1985
  • Two classes of binding sites for uncoating protein in clathrin triskelions.  260:10050-10056. 1985
  • Two mutations in the dispensable part of alanine tRNA synthetase which affect the catalytic activity.  260:2226-2230. 1985
  • 2-Propylthiouracil does not replace glutathione for the glutathione transferases.  259:7409-7410. 1984
  • A monoclonal-antibody recognizes an o-acylated sialic-acid in a human melanoma-associated ganglioside.  259:7453-7459. 1984
  • Anti-apoprotein-b monoclonal-antibodies detect human low-density lipoprotein polymorphism.  259:6423-6430. 1984
  • Biosynthetic-studies of proteoglycans in human-melanoma cells with a monoclonal-antibody to a core glycoprotein of chondroitin sulfate proteoglycans.  259:2733-2741. 1984
  • Demonstration of peptide-n-glycosidase-f activity in endo-beta-n-acetylglucosaminidase f preparations.  259:700-704. 1984
  • Erythrocyte membrane tropomyosin. Purification and properties.  259:5978-5989. 1984
  • Evidence for participation of a multiprotein complex in yeast DNA replication in vitro.  259:6852-6857. 1984
  • Metal dissociation constants for glyoxalase I reconstituted with Zn2+, Co2+, Mn2+, and Mg2+.  259:11426-11429. 1984
  • NMR and computer modeling studies of the conformations of glutathione derivatives at the active site of glyoxalase I.  259:11436-11447. 1984
  • Purification and characterization of the rieske iron-sulfur protein from thermus-thermophilus - evidence for a 2fe-2s cluster having non-cysteine ligands.  259:124-133. 1984
  • Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells.  259:14914-14921. 1984
  • Rabbit muscle creatine phosphokinase. CDNA cloning, primary structure and detection of human homologues.  259:14317-14320. 1984
  • Respiratory proteins from the extremely thermophilic aerobic bacterium, thermus-thermophilus - purification procedures for cytochrome-c552, cytochrome-c555,549, and cytochrome-c1aa3 and chemical evidence for a single subunit cytochrome-aa3.  259:112-123. 1984
  • Studies on cytochrome-c oxidase activity of the cytochrome-c1aa3 complex from thermus-thermophilus.  259:1031-1036. 1984
  • The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil.  259:5661-5669. 1984
  • Three monoclonal antibodies to rabbit microsomal cytochrome P-450 1 recognize distinct epitopes that are shared to different degrees among other electrophoretic types of cytochrome P-450.  259:5887-5892. 1984
  • Yeast LEU1. Repression of mRNA levels by leucine and relationship of 5'-noncoding region to that of LEU2.  259:3714-3719. 1984
  • Yeast LEU2. Repression of mRNA levels by leucine and primary structure of the gene product.  259:8059-8062. 1984
  • 13C NMR studies of the product complex of glyoxalase I.  258:6823-6826. 1983
  • Allosteric regulation of the 16-alpha-hydroxylation of progesterone as catalyzed by rabbit microsomal cytochrome-p-450-3b.  258:2785-2788. 1983
  • An endopeptidase inhibitor, similar to mammalian alpha-2-macroglobulin, detected in the hemolymph of an invertebrate, limulus-polyphemus.  258:7903-7906. 1983
  • Characterization of 3-iron ferredoxins by means of the linear electric-field effect in electron-paramagnetic-res.  258:3014-3016. 1983
  • Comparison of the 34,000-da pp60src substrate and a 38,000-da phosphoprotein identified by monoclonal-antibodies.  258:8497-8502. 1983
  • Cyclic GMP efflux from liver slices.  258:6882-6886. 1983
  • Detection of a nucleolar 7-2 ribonucleoprotein and a cytoplasmic 8-2 ribonucleoprotein with autoantibodies from patients with scleroderma.  258:1383-1386. 1983
  • Identification of a La protein binding site in a RNA polymerase III transcript (4.5 I RNA).  258:8352-8356. 1983
  • In vitro association of a replication complex with a yeast chromosomal replicator.  258:2754-2757. 1983
  • Isolation and functional-characterization of the active light chain of activated human-blood coagulation factor-XI.  258:9669-9675. 1983
  • Leghemoglobin .6. Kinetic, nuclear magnetic-resonance, and optical studies of ph-dependence of oxygen and carbon-monoxide binding.  258:2254-2259. 1983
  • Mossbauer study of beef-heart cytochrome-oxidase - comparative-study of the bovine enzyme and cytochrome-c1aa3 from thermus-thermophilus.  258:8543-8546. 1983
  • Octahedral metal coordination in the active site of glyoxalase I as evidenced by the properties of Co(II)-glyoxalase I.  258:2091-2093. 1983
  • Photoaffinity labeling of the N-formyl peptide receptor binding site of intact human polymorphonuclear leukocytes. A label suitable for following the fate of the receptor-ligand complex.  258:649-654. 1983
  • Primary structures of both subunits of Escherichia coli glycyl-tRNA synthetase.  258:637-641. 1983
  • Reversal of the reaction catalyzed by glyoxalase I. Calculation of the equilibrium constant for the enzymatic reaction.  258:8872-8875. 1983
  • Single-crystals of cadmium, zinc metallothionein.  258:6255-6257. 1983
  • Structure of azotobacter-vinelandii 7fe ferredoxin - amino-acid-sequence and electron-density maps of residues.  258:508-522. 1983
  • Studies of the ferredoxin from thermus-thermophilus.  258:3008-3013. 1983
  • Sulfatide-dependent autoactivation of human-blood coagulation Factor-XII (Hageman-factor).  258:8215-8222. 1983
  • The fate of an N-formylated chemotactic peptide in stimulated human granulocytes. Subcellular fractionation studies.  258:1968-1977. 1983
  • The interaction of arsenite with xanthine-oxidase.  258:4849-4856. 1983
  • The primary structure of the alcohol dehydrogenase gene from the fission yeast Schizosaccharomyces pombe.  258:143-149. 1983
  • The t3-complex on human lymphocytes-t involves 4 structurally distinct glycoproteins.  258:5135-5141. 1983
  • A continuous, spectroscopic analysis of the kinetics of elastase secretion by neutrophils. The dependence of secretion upon receptor occupancy.  257:5471-5475. 1982
  • A high-yield purification procedure for alpha-chain and beta-chain of hla-dr antigens.  257:7940-7943. 1982
  • A study of the electron-paramagnetic resonance properties of single monoclinic crystals of bovine superoxide-dismutase.  257:336-344. 1982
  • Binary combinations of four protein subunits with different catalytic specificities explain the relationship between six basic glutathione S-transferases in rat liver cytosol.  257:9909-9912. 1982
  • Chemical characterization of a neural cell-adhesion molecule purified from embryonic brain membranes.  257:7720-7729. 1982
  • Differences in the carbohydrate structures of neural cell-adhesion molecules from adult and embryonic chicken brains.  257:1064-1069. 1982
  • Functional and structural polymorphism of rabbit microsomal cytochrome P-450 form 3b.  257:9315-9323. 1982
  • Gene for Escherichia coli glycyl-tRNA synthetase has tandem subunit coding regions in the same reading frame.  257:12503-12508. 1982
  • Identification of a gal-beta-1 - 3glcnac alpha-2 - 3 sialyltransferase in rat-liver.  257:4034-4037. 1982
  • Immunochemical heterogeneity of human-plasma apolipoprotein-b .1. Apolipoprotein-b binding of mouse hybridoma antibodies.  257:5213-5221. 1982
  • Immunochemical heterogeneity of human-plasma apolipoprotein-b .2. Expression of apolipoprotein-b epitopes on native lipoproteins.  257:5222-5228. 1982
  • Isolation and functional-properties of the heavy and light-chains of human-plasma kallikrein.  257:4300-4305. 1982
  • Mossbauer study of a bacterial cytochrome-oxidase - cytochrome c1aa3 from thermus-thermophilus.  257:2489-2492. 1982
  • Newcastle-disease virus contains a linkage-specific glycoprotein sialidase - application to the localization of sialic-acid residues in n-linked oligosaccharides of alpha-1 acid glycoprotein.  257:2734-2738. 1982
  • Nuclear relaxation studies of the role of the essential metal in glyoxalase I.  257:10023-10029. 1982
  • Purification of a gal-beta-1- 4glcnac alpha-2- 6 sialyltransferase and a gal-beta-1- 3(4)glcnac alpha-2- 3 sialyltransferase to homogeneity from rat-liver.  257:3835-3844. 1982
  • Sialylation of glycoprotein oligosaccharides n-linked to asparagine - enzymatic characterization of a gal-beta-1- 3(4)glcnac alpha-2- 3 sialyltransferase and a gal-beta-1- 4glcnac alpha-2- 6 sialyltransferase from rat-liver.  257:3845-3853. 1982
  • Single-crystals of the iron-sulfur enzyme aconitase.  257:9061-9063. 1982
  • Spin state and unfolding equilibria of ferricytochrome c in acidic solutions.  257:2267-2273. 1982
  • The in vitro transcription-translation of DNA and RNA templates by extracts of Rhodopseudomonas sphaeroides. Optimization and comparison of template specificity with Escherichia coli extracts and in vivo synthesis.  257:5110-5121. 1982
  • Amino acid sequence of an analogous peptide from two forms of cytochrome P-450.  256:1405-1408. 1981
  • An inhibitor of plasminogen activator in rabbit endothelial cells.  256:4142-4145. 1981
  • Characterization of crystals of tetrameric manganese superoxide-dismutase from thermus-thermophilus hb8.  256:5857-5859. 1981
  • Cloning, partial sequencing, and in vitro transcription of the gene for alanine tRNA synthetase.  256:205-211. 1981
  • Different cell-surface receptor determinants of antigenically similar influenza-virus hemagglutinins.  256:8357-8363. 1981
  • Equilibrium properties of xanthine-oxidase containing fad analogs of varying oxidation-reduction potential.  256:8933-8940. 1981
  • Immunochemical mapping of the conformation of human-fibrinogen - the gamma-95-264 segment is inaccessible to antibody in native fibrinogen but progressively exposed by plasmic cleavage.  256:8018-8023. 1981
  • In vitro transcription of the histidine operon. Identification of the his promoter and leader and readthrough transcripts.  256:10747-10750. 1981
  • Purification and properties of alanine tRNA synthetase from Escherichia coli. A tetramer of identical subunits.  256:198-204. 1981
  • Specificity in the activation and inhibition by flavonoids of benzo alpha pyrene hydroxylation by cytochrome-p-450 isozymes from rabbit liver-microsomes.  256:897-901. 1981
  • Stimulation of pituitary gonadotropin release does not require internalization of gonadotropin-releasing hormone.  256:1098-1100. 1981
  • Structure of a 7fe ferredoxin from azotobacter-vinelandii.  256:4185-4192. 1981
  • Superoxide-dismutase - examination of the metal-binding sites by electron-spin echo spectroscopy.  256:1910-1914. 1981
  • The kinetics of neutrophil activation. The response to chemotactic peptides depends upon whether ligand-receptor interaction is rate-limiting.  256:9909-9914. 1981
  • The structure of the lentil (lens-culinaris) lectin - amino-acid-sequence determination and prediction of the secondary structure.  256:5550-5560. 1981
  • Binding of 2-hydroxyestradiol to rat anterior pituitary cell membranes.  255:9838-9843. 1980
  • Immunochemical studies of human high molecular-weight kininogen and of its complexes with plasma prekallikrein or kallikrein.  255:3952-3958. 1980
  • Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in adp-induced platelet-aggregation.  255:154-161. 1980
  • Iron-sulfur clusters in azotobacter ferredoxin at 2.5 a resolution.  255:1797-1800. 1980
  • Isolation and characterization of a constitutive form of rabbit liver microsomal cytochrome P-450.  255:304-309. 1980
  • Kinetic studies on muscarinic antagonist-agonist competition.  255:2649-2651. 1980
  • Affinity labeling of creatine kinase by N-(2,3-epoxypropyl)-N-amidinoglycine.  254:1879-1886. 1979
  • Aminoacyl-tRNA synthetase-catalyzed cleavage of the glycosidic bond of 5-halogenated uridines.  254:12277-12280. 1979
  • Biosynthesis of mammalian glycoproteins - glycosylation pathways in the synthesis of the nonreducing terminal sequences.  254:2531-2541. 1979
  • Carbohydrate composition and identification of blood group A, B, and H oligosaccharide structures on human Factor VIII/von Willebrand factor.  254:754-760. 1979
  • Enzymatic characterization of beta-d-galactoside alpha-2- 3 sialytransferase from porcine sub-maxillary gland.  254:4444-4451. 1979
  • Evidence for essential disulfide bonds in beta-1-adrenergic receptors of turkey erythrocyte-membranes - inactivation by dithiothreitol.  254:4462-4469. 1979
  • Human high molecular-weight kininogen - studies of structure-function-relationships and of proteolysis of the molecule occurring during contact activation of plasma.  254:2020-2027. 1979
  • Human-platelets possess an inducible and saturable receptor specific for fibrinogen.  254:5357-5363. 1979
  • Identification of a nuclear protein (Scl-70) as a unique target of human antinuclear antibodies in scleroderma.  254:10514-10522. 1979
  • Isolation and characterization of nuclear ribonucleoprotein complexes using human anti-nuclear ribonucleoprotein antibodies.  254:3608-3616. 1979
  • Isomerization of the muscarinic receptor . antagonist complex.  254:5595-5598. 1979
  • Localization and characterization of the cleavage-associated neoantigen locus in the e-domain of fibrinogen.  254:672-678. 1979
  • Metal-free southern bean mosaic-virus crystals.  254:5243-5245. 1979
  • Purification to homogeneity of a beta-galactoside alpha-2- 3 sialytransferase and partial-purification of an alpha-n-acetylgalactosaminide alpha-2- 6 sialytransferase from porcine sub-maxillary glands.  254:4434-4442. 1979
  • Restoration of specific myxovirus receptors to asialoerythrocytes by incorporation of sialic-acid with pure sialytransferases.  254:2120-2124. 1979
  • Role of sialic-acid in the expression of human mn blood-group antigens.  254:2112-2119. 1979
  • The binding of substrates and a product of the enzymatic reaction to glutathione S-transferase A.  254:7085-7089. 1979
  • Two crystal forms of Azotobacter ferredoxin.  254:3598-3599. 1979
  • Binding and functional properties of concanavalin-a and its derivatives .1. Mono-valent, divalent, and tetravalent derivatives stable at physiological ph.  253:3000-3007. 1978
  • Binding and functional properties of concanavalin-a and its derivatives .2. Proteolytic product with saccharide-binding activity.  253:3008-3015. 1978
  • Binding and functional properties of concanavalin-a and its derivatives .3. Interactions with indoleacetic-acid and other hydrophobic ligands.  253:3016-3022. 1978
  • Carbohydrate on human factor viii von willebrand factor - impairment of function by removal of specific galactose residues.  253:7202-7206. 1978
  • Human-blood coagulation factor-IX - purification, properties, and mechanism of activation by activated factor-XI.  253:5946-5951. 1978
  • Identification of major cytochrome-P-450 form transplacentally induced in neonatal rabbits by 2,3,7,8-tetrachlorodibenzo-p-dioxin.  253:8640-8647. 1978
  • Major developmentally regulated protein complex in membranes of dictyostelium.  253:5133-5139. 1978
  • Sialyltransferases and fucosyltransferases in biosynthesis of asparaginyl-linked oligosaccharides in glycoproteins - mutually exclusive glycosylation by beta-galactoside -alpha-2- 6-sialyltransferase and n-acetylglucosaminide -alpha-1- 3-fucosyltransferase.  253:5617-5624. 1978
  • Adhesion among neural cells of chick-embryo .1. Immunological assay for molecules involved in cell-cell binding.  252:6835-6840. 1977
  • Adhesion among neural cells of chick-embryo .2. Purification and characterization of a cell-adhesion molecule from neural retina.  252:6841-6845. 1977
  • Aspartate-transcarbamylase lacking catalytic subunit interactions - study of conformational-changes by uv absorbance and circular-dichroism spectroscopy.  252:2881-2890. 1977
  • Enzymatic properties of beta-d-galactoside alpha-2- 6 sialyltransferase from bovine colostrum.  252:2363-2371. 1977
  • Human blood coagulation factor-XI - purification, properties, and mechanism of activation by activated factor-XII.  252:6432-6437. 1977
  • Immunochemical homology between a-alpha and a d.E complex-dependent site of gamma chains of fibrinogen.  252:8917-8923. 1977
  • Purification of a sialyltransferase from bovine colostrum by affinity chromatography on cdp-agarose.  252:2356-2362. 1977
  • Radioiodination of proteins in single polyacrylamide-gel slices - tryptic peptide analysis of all major members of complex multicomponent systems using microgram quantities of total protein.  252:6510-6515. 1977
  • Reactivation of asialo-rabbit liver binding-protein by resialylation with beta-d-galactoside alpha2- 6 sialyltransferase.  252:8624-8628. 1977
  • Resolution of 2 forms of cytochrome-P-450 from liver-microsomes of rabbits treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.  252:2839-2845. 1977
  • Revised amino-acid sequence of qbeta coat protein between positions 1 and 60.  252:990-993. 1977
  • Systematic purification of 5 glycosidases from streptococcus-(diplococcus)-pneumoniae.  252:8615-8623. 1977
  • Direct evidence for manganese(iii) binding to manganosuperoxide dismutase of escherichia-coli-b.  251:6157-6159. 1976
  • Formation of hybrid concanavalin-a molecules by subunit exchange.  251:4622-4628. 1976
  • Isotope labeling of free and aminoacyl transfer RNA synthetase-bound transfer RNA.  251:6823-6830. 1976
  • Muscarinic acetylcholine receptor from rat brain. Partial purification and characterization.  251:1543-1547. 1976
  • Physical and chemical studies on bacterial superoxide dismutases - purification and some anion binding properties of iron-containing protein of escherichia-coli-b.  251:5472-5477. 1976
  • Synthesis in vitro of intrinsic membrane proteins by free, membrane-bound, and golgi apparatus-associated polyribosomes from rat-liver.  251:5054-5068. 1976
  • The ovalbumin gene. Partial purification of the coding strand.  251:3868-3874. 1976
  • Cleavage-associated neoantigenic marker for a gamma chain site in nh2-terminal aspect of fibrinogen molecule.  250:3386-3392. 1975
  • Complement activation by a univalent hapten-antibody complex.  250:4918-4925. 1975
  • Conformational and structural modulation of nh2-terminal regions of fibrinogen and fibrin associated with plasmin cleavage.  250:3393-3398. 1975
  • Covalent and 3-dimensional structure of concanavalin-a .1. Amino-acid sequence of cyanogen-bromide fragments f1 and f2.  250:1490-1502. 1975
  • Covalent and 3-dimensional structure of concanavalin-a .2. Amino-acid sequence of cyanogen-bromide fragment f3.  250:1503-1512. 1975
  • Covalent and 3-dimensional structure of concanavalin-a .3. Structure of monomer and its interactions with metals and saccharides.  250:1513-1524. 1975
  • Covalent and 3-dimensional structure of concanavalin-a .4. Atomic coordinates, hydrogen-bonding, and quaternary structure.  250:1525-1547. 1975
  • Interactions of bovine neurophysins with neurohypophyseal hormones - role of tyrosine-49.  250:5215-5220. 1975
  • Isolation of lectins of different specificities on a single affinity adsorbent.  250:7535-7538. 1975
  • Progesterone binding components of chick oviduct. X. Purification by affinity chromatography.  250:4220-4228. 1975
  • Purification and characterization of the flavoenzyme glutathione reductase from rat liver.  250:5475-5480. 1975
  • Three photo-cross-linked complexes of yeast phenylalanine specific transfer ribonucleic acid with aminoacyl transfer ribonucleic acid synthetases.  250:4440-4444. 1975
  • Two photo-cross-linked complexes of isoleucine specific transfer ribonucleic acid with aminoacyl transfer ribonucleic acid synthetases.  250:4433-4439. 1975
  • Binding of steroids to progesterone receptor proteins in chick oviduct and human uterus.  249:5924-5932. 1974
  • Fibrinolysis associated with oncogenic transformation. Morphological correlates.  249:4312-4320. 1974
  • Interactions of bovine neurophysin-II with oxytocin and 8-lysine vasopressin - high-resolution proton nuclear magnetic-resonance spectroscopy studies.  249:6895-6900. 1974
  • Plasminogen, the serum proenzyme activated by factors from cells transformed by oncogenic viruses.  249:4306-4311. 1974
  • Random pathway mechanism involving parallel one- and two- substrate branches for glyoxalase i from yeast.  249:901-903. 1974
  • Rotational correlation time of concanavalin-a after interaction with a fluorescent-probe.  249:7018-7023. 1974
  • Carbamyl phosphate binding to aspartate transcarbamylase. Partial saturation and its alteration by succinate.  248:5063-5066. 1973
  • Complex-formation between bovine neurophysin-I and oxytocin, vasopressin, and tripeptide analogs of their NH2-terminal region - absorbance and circular-dichroism difference spectroscopic studies.  248:7975-7978. 1973
  • Conformational changes in aspartate transcarbamylase. II. Circular dichroism evidence for the involvement of metal ions in allosteric interactions.  248:5057-5062. 1973
  • Nuclear magnetic resonance titration curves of histidine ring protons. IV. The effects of phosphate and sulfate on ribonuclease.  248:4305-4310. 1973
  • Preliminary report on the electron paramagnetic resonance spectra of single crystals of bovine erythrocyte superoxide dismutase.  248:7617-7619. 1973
  • Studies on reconstitution of bovine erythrocyte superoxide dismutase .4. Preparation and some properties of enzyme in which co(ii) is substituted for zn(ii).  248:4229-4234. 1973
  • The stereochemistry of pyridoxal phosphate enzymes. The absolute stereochemistry of cofactor c' 4 protonation in the transamination of holoserine hydroxymethylase by d-alanine.  248:841-842. 1973
  • Conformational changes in aspartate trancarbamylase. I. Studies of ligand binding and of subunit interactions by circular dichroism spectroscopy.  247:6482-6490. 1972
  • Rapid deacylation by isoleucyl transfer ribonucleic acid synthetase of isoleucine-specific transfer ribonucleic acid aminoacylated with valine.  247:2961-2964. 1972
  • Conformational changes in concanavalin a.  246:4369-4370. 1971
  • Fluorescent probes for conformational states of proteins. Iv. The pepsinogen-pepsin conversion.  246:1185-1191. 1971
  • Location of the saccharide binding site of concanavalin a.  246:6123-6125. 1971
  • High resolution proton magnetic resonance studies of cyanoferrimyoglobins and alkylated derivatives from different species.  245:1947-1953. 1970
  • Removal of the 4,4-dimethyl carbons in the enzymic conversion of lanosterol to cholesterol. Initial loss of the 4-alpha-methyl group.  245:2667-2671. 1970
  • The purification and properties of bovine thrombin.  245:4857-4862. 1970
  • Interaction of human hemoglobin with adenine nucleotides.  244:5084-5086. 1969
  • Interaction of lysozyme with alpha-N-acetyl-D-glucosamine.  244:3643-3646. 1969
  • Properties of deoxyribonuclease 3 from mammalian tissues.  244:5014-5019. 1969
  • Dynamics of lysozyme-saccharide interactions.  243:3771-3774. 1968
  • Isolation and chemical properties of porcine thyrocalcitonin.  243:5739-5747. 1968
  • Isolation of an acidic protein from rat brain.  243:6234-6241. 1968
  • Squalene-2,3-oxide, an intermediate in the enzymatic conversion of squalene to lanosterol and cholesterol.  242:4182-4191. 1967
  • Characterization of sheep prolactin.  239:1777-1782. 1964

abbreviation

  • J Biol Chem
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Identity

International Standard Serial Number (ISSN)

  • 0021-9258

Electronic International Standard Serial Number (EISSN)

  • 1083-351X

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