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Relation of an elevated white blood cell count after percutaneous coronary intervention to long-term mortality

Academic Article
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Overview

authors

  • Rajagopal, V.
  • Gurm, H. S.
  • Bhatt, D. L.
  • Lincoff, A. M.
  • Tcheng, J. E.
  • Kereiakes, D. J.
  • Kleiman, N. S.
  • Jia, G.
  • Topol, Eric

publication date

  • July 2004

journal

  • American Journal of Cardiology  Journal

abstract

  • Increased inflammatory markers are associated with a poor prognosis after percutaneous coronary intervention. Leukocytes play a key role in inflammation, and an increase in white blood cell (WBC) counts is a nonspecific marker of inflammation. In patients undergoing percutaneous coronary intervention, baseline WBC counts independently predict long-term mortality. In a pooled cohort of patients from the Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC), the Evaluation in PTCA to Improve Long-term Outcome with abciximab Glycoprotein IIb/IIIa blockade (EPILOG), and Evaluation of Platelet IIb/IIIa inhibitor for STENTing (EPISTENT) trials, postprocedural WBC counts were also found to be an independent predictor of long-term mortality.

subject areas

  • Aged
  • Angioplasty, Balloon, Coronary
  • Coronary Disease
  • Female
  • Humans
  • Leukocyte Count
  • Male
  • Middle Aged
  • Multicenter Studies as Topic
  • Multivariate Analysis
  • Prognosis
  • Randomized Controlled Trials as Topic
  • Retrospective Studies
  • Survival Analysis
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Identity

International Standard Serial Number (ISSN)

  • 0002-9149

Digital Object Identifier (DOI)

  • 10.1016/j.amjcard.2004.03.060

PubMed ID

  • 15246898
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Additional Document Info

start page

  • 190

end page

  • 192

volume

  • 94

issue

  • 2

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