recent publications

• academic article

  • Tyagi, N. K., Fenton, W. A., Deniz, A. A., Horwich, A. L. Double mutant MBP refolds at same rate in free solution as inside the GroEL/GroES chaperonin chamber when aggregation in free solution is prevented FEBS Letters  2011 585:1969-1972  DOI:10.1016/j.febslet.2011.05.031  PMID:21609718  PMCID:PMC3144026
  • Chapman, E., Farr, G. W., Fenton, W. A., Johnson, S. M., Horwich, A. L. Requirement for binding multiple ATPs to convert a GroEL ring to the folding-active state Proceedings of the National Academy of Sciences of the United States of America  2008 105:19205-19210  DOI:10.1073/pnas.0810657105  PMID:19050077  PMCID:PMC2592988
  • Horst, R., Fenton, W. A., Englander, S. W., Wuthrich, K., Horwich, A. L. Folding trajectories of human dihydrofolate reductase inside the GroEL GroES chaperonin cavity and free in solution Proceedings of the National Academy of Sciences of the United States of America  2007 104:20788-20792  DOI:10.1073/pnas.0710042105  PMID:18093916  PMCID:PMC2410080
  • Chapman, E., Farr, G. W., Usaite, R., Furtak, K., Fenton, W. A., Chaudhuri, T. K., Hondorp, E. R., Matthews, R. G., Wolf, S. G., Yates, J. R., Pypaert, M., Horwich, A. L. Global aggregation of newly translated proteins in an Escherichia coli strain deficient of the chaperonin GroEL Proceedings of the National Academy of Sciences of the United States of America  2006 103:15800-15805  DOI:10.1073/pnas.0607534103  PMID:17043235  PMCID:PMC1613232