recent publications

• academic article

  • Kissner, T. L., Ruthel, G., Alam, S., Mann, E., Ajami, D., Rebek, M., Larkin, E., Fernandez, S., Ulrich, R. G., Ping, S., Waugh, D. S., Rebek, J., et al. Therapeutic inhibition of pro-inflammatory signaling and toxicity to staphylococcal enterotoxin b by a synthetic dimeric bb-loop mimetic of myd88 PLoS One  2012 7:e40773  DOI:10.1371/journal.pone.0040773  PMID:22848400  PMCID:PMC3407147
  • Kissner, T. L., Moisan, L., Mann, E., Alam, S., Ruthel, G., Ulrich, R. G., Rebek, M., Rebek, J., Saikh, K. U. A small molecule that mimics the BB-loop in the Toll Interleukin-1 (IL-1) receptor domain of MyD88 attenuates Staphylococcal enterotoxin B-induced pro-inflammatory cytokine production and toxicity in mice Journal of Biological Chemistry  2011 286:31385-31396  DOI:10.1074/jbc.M110.204982  PMID:21693701  PMCID:PMC3173059
  • Mann, E., Rebek, J. Deepened chiral cavitands Tetrahedron  2008 64:8484-8487  DOI:10.1016/j.tet.2008.05.136
  • Mann, E., Moisan, L., Hou, J. L., Rebek, J. Synthesis of pyridazines functionalized with amino acid side chains Tetrahedron Letters  2008 49:903-905  DOI:10.1016/j.tetlet.2007.11.149
  • Moisan, L., Dale, T. J., Gombosuren, N., Biros, S. M., Mann, E., Hou, J. L., Crisostomo, F. P., Rebek, J. Facile synthesis of pyridazine-based α-helix mimetics Heterocycles  2007 73:661-671  DOI:10.3987/COM-07-S(U)45
  • Biros, S. M., Moisan, L., Mann, E., Carella, A., Zhai, D., Reed, J. C., Rebek, J. Heterocyclic alpha-helix mimetics for targeting protein-protein interactions Bioorganic & Medicinal Chemistry Letters  2007 17:4641-4645  DOI:10.1016/j.bmcl.2007.05.075  PMID:17555961  PMCID:PMC2699934
  • Iwasawa, T., Mann, E., Rebek, J. A reversible reaction inside a self-assembled capsule Journal of the American Chemical Society  2006 128:9308-9309  DOI:10.1021/ja062768a  PMID:16848447
  • Davis, C. N., Mann, E., Behrens, M. M., Gaidarova, S., Rebek, M., Rebek, J., Bartfai, T. MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics Proceedings of the National Academy of Sciences of the United States of America  2006 103:2953-2958  DOI:10.1073/pnas.0510802103  PMID:16477040  PMCID:PMC1413805