Structural basis for amide hydrolysis catalyzed by the 43C9 antibody

Academic Article

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• Research
• Identity
• Additional Document Info
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Overview

authors

• Thayer, M. M.
• Olender, E. H.
• Arvai, A. S.
• Koike, C. K.
• Canestrelli, I. L.
• Stewart, J. D.
• Benkovic, S. J.
• Getzoff, Elizabeth
• Roberts, V. A.

publication date

• August 1999

journal

• Journal of Molecular Biology  Journal

subject areas

• Amides
• Amino Acid Sequence
• Antibodies, Catalytic
• Binding Sites, Antibody
• Catalysis
• Cell Line, Transformed
• Complementarity Determining Regions
• Computer Simulation
• Crystallography, X-Ray
• Hydrolysis
• Immunoglobulin Fragments
• Immunoglobulin Variable Region
• Models, Molecular
• Molecular Sequence Data
• Nitrophenols
• Protein Conformation
• Structure-Activity Relationship
• Substrate Specificity
• Tryptophan

Research

keywords

• X-ray crystallography
• amide hydrolysis
• antibody structure
• antibody-antigen interactions
• catalytic antibody

Identity

International Standard Serial Number (ISSN)

• 0022-2836

Digital Object Identifier (DOI)

• 10.1006/jmbi.1999.2960

PubMed ID

• 10438624

Additional Document Info

start page

• 329

end page

• 345

volume

• 291

issue

• 2