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Structural basis for amide hydrolysis catalyzed by the 43C9 antibody

Academic Article
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  • Research
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Overview

authors

  • Thayer, M. M.
  • Olender, E. H.
  • Arvai, A. S.
  • Koike, C. K.
  • Canestrelli, I. L.
  • Stewart, J. D.
  • Benkovic, S. J.
  • Getzoff, Elizabeth
  • Roberts, V. A.

publication date

  • August 1999

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Amides
  • Amino Acid Sequence
  • Antibodies, Catalytic
  • Binding Sites, Antibody
  • Catalysis
  • Cell Line, Transformed
  • Complementarity Determining Regions
  • Computer Simulation
  • Crystallography, X-Ray
  • Hydrolysis
  • Immunoglobulin Fragments
  • Immunoglobulin Variable Region
  • Models, Molecular
  • Molecular Sequence Data
  • Nitrophenols
  • Protein Conformation
  • Structure-Activity Relationship
  • Substrate Specificity
  • Tryptophan
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Research

keywords

  • X-ray crystallography
  • amide hydrolysis
  • antibody structure
  • antibody-antigen interactions
  • catalytic antibody
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1006/jmbi.1999.2960

PubMed ID

  • 10438624
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Additional Document Info

start page

  • 329

end page

  • 345

volume

  • 291

issue

  • 2

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