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Therapy of chronic idiopathic thrombocytopenic purpura in adults

Academic Article
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Overview

authors

  • Berchtold, P.
  • Mc Millan, Robert

publication date

  • November 1989

journal

  • Blood  Journal

abstract

  • Chronic ITP is a common hematologic illness. Approximately three fourths of the patients respond to corticosteroids or splenectomy and need no further treatment. Patients refractory to these two therapeutic approaches are relatively resistant to present forms of treatment and are at much greater risk for morbidity and mortality. Future clinical studies evaluating therapy in this refractory group would be best performed in a cooperative group setting in which large numbers of patients could be treated in a prospective randomized manner.

subject areas

  • Adrenal Cortex Hormones
  • Adult
  • Antibodies, Monoclonal
  • Ascorbic Acid
  • Autoimmune Diseases
  • Azathioprine
  • Colchicine
  • Cyclophosphamide
  • Cyclosporins
  • Danazol
  • Female
  • Humans
  • Methylprednisolone
  • Plasmapheresis
  • Platelet Transfusion
  • Pregnancy
  • Pregnancy Complications, Hematologic
  • Purpura, Thrombocytopenic
  • Splenectomy
  • Vinca Alkaloids
  • gamma-Globulins
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Identity

International Standard Serial Number (ISSN)

  • 0006-4971

PubMed ID

  • 2478227
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Additional Document Info

start page

  • 2309

end page

  • 2317

volume

  • 74

issue

  • 7

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