recent publications

• academic article

  • Lysek, D. A., Schorn, C., Nivon, L. G., Esteve-Moya, V., Christen, B., Calzolai, L., von Schroetter, C., Fiorito, F., Herrmann, T., Guntert, P., Wuthrich, K. Prion protein NMR structures of cats, dogs, pigs, and sheep Proceedings of the National Academy of Sciences of the United States of America  2005 102:640-645  DOI:10.1073/pnas.0408937102  PMID:15647367  PMCID:PMC545531
  • Calzolai, L., Lysek, D. A., Perez, D. R., Guntert, P., Wuthrich, K. Prion protein NMR structures of chickens, turtles, and frogs Proceedings of the National Academy of Sciences of the United States of America  2005 102:651-655  DOI:10.1073/pnas.0408939102  PMID:15647366  PMCID:PMC545536
  • Fernandez, C., Hilty, C., Wider, G., Guntert, P., Wuthrich, K. NMR structure of the integral membrane protein OmpX Journal of Molecular Biology  2004 336:1211-1221  DOI:10.1016/j.jmb.2003.09.014  PMID:15037080
  • Luhrs, T., Riek, R., Guntert, P., Wuthrich, K. NMR structure of the human doppel protein Journal of Molecular Biology  2003 326:1549-1557  DOI:10.1016/s0022-2836(02)01471-7  PMID:12595265
  • Zahn, R., Guntert, P., von Schroetter, C., Wuthrich, K. Nmr structure of a variant human prion protein with two disulfide bridges Journal of Molecular Biology  2003 326:225-234  DOI:10.1016/s0022-2836(02)01332-3  PMID:12547204
  • Lee, D., Damberger, F. F., Peng, G. H., Horst, R., Guntert, P., Nikonova, L., Leal, W. S., Wuthrich, K. Nmr structure of the unliganded bombyx mori pheromone-binding protein at physiological ph FEBS Letters  2002 531:314-318  DOI:10.1016/s0014-5793(02)03548-2  PMID:12417333
  • Ellgaard, L., Bettendorff, P., Braun, D., Herrmann, T., Fiorito, F., Jelesarov, M., Guntert, P., Helenius, A., Wuthrich, K. Nmr structures of 36 and 73-residue fragments of the calreticulin p-domain Journal of Molecular Biology  2002 322:773-784  DOI:10.1016/s0022-2936(02)00812-4  PMID:12270713
  • Herrmann, T., Guntert, P., Wuthrich, K. Protein NMR structure determination with automated noe assignment using the new software candid and the torsion angle dynamics algorithm dyana Journal of Molecular Biology  2002 319:209-227  DOI:10.1016/s0022-2836(02)00241-3  PMID:12051947
  • Herrmann, T., Guntert, P., Wuthrich, K. Protein NMR structure determination with automated noe-identification in the noesy spectra using the new software atnos Journal of Biomolecular NMR  2002 24:171-189  DOI:10.1023/a:1021614115432  PMID:12522306
  • Ellgaard, L., Riek, R., Herrmann, T., Guntert, P., Braun, D., Helenius, A., Wuthrich, K. NMR structure of the calreticulin p-domain Proceedings of the National Academy of Sciences of the United States of America  2001 98:3133-3138  DOI:10.1073/pnas.051630098  PMID:11248044  PMCID:PMC30619
  • Horst, R., Damberger, F., Luginbuhl, P., Guntert, P., Peng, G., Nikonova, L., Leal, W. S., Wuthrich, K. Nmr structure reveals intramolecular regulation mechanism for pheromone binding and release Proceedings of the National Academy of Sciences of the United States of America  2001 98:14374-14379  DOI:10.1073/pnas.251532998  PMID:11724947  PMCID:PMC64689
  • Riek, R., Guntert, P., Dobeli, H., Wipf, B., Wuthrich, K. Nmr studies in aqueous solution fail to identify significant conformational differences between the monomeric forms of two alzheimer peptides with widely different plaque-competence, a beta(1-40)(ox) and a beta(1-42)(ox) European Journal of Biochemistry  2001 268:5930-5936  DOI:10.1046/j.0014-2956.2001.02537.x  PMID:11722581
  • Guntert, P., Wuthrich, K. Sampling of conformation space in torsion angle dynamics calculations Computer Physics Communications  2001 138:155-169  DOI:10.1016/s0010-4655(01)00204-1
  • Calzolai, L., Lysek, D. A., Guntert, P., von Schroetter, C., Riek, R., Zahn, R., Wuthrich, K. Nmr structures of three single-residue variants of the human prion protein Proceedings of the National Academy of Sciences of the United States of America  2000 97:8340-8345  DOI:10.1073/pnas.97.15.8340  PMID:10900000
  • Guntert, P., Salzmann, M., Braun, D., Wuthrich, K. Sequence-specific NMR assignment of proteins by global fragment mapping with the program mapper Journal of Biomolecular NMR  2000 18:129-137  DOI:10.1023/a:1008318805889  PMID:11101217
  • Riek, R., Precheur, B., Wang, Y. Y., Mackay, E. A., Wider, G., Guntert, P., Liu, A. Z., Kagi, J. H. R., Wuthrich, K. Nmr structure of the sea urchin (strongylocentrotus purpuratus) metallothionein mta Journal of Molecular Biology  1999 291:417-428  DOI:10.1006/jmbi.1999.2967  PMID:10438629
  • Koradi, R., Billeter, M., Engeli, M., Guntert, P., Wuthrich, K. Automated peak picking and peak integration in macromolecular NMR spectra using autopsy Journal of Magnetic Resonance  1998 135:288-297  DOI:10.1006/jmre.1998.1570  PMID:9878459
  • Guntert, P., Billeter, M., Ohlenschlager, O., Brown, L. R., Wuthrich, K. Conformational analysis of protein and nucleic acid fragments with the new grid search algorithm found Journal of Biomolecular NMR  1998 12:543-548  DOI:10.1023/a:1008391403193  PMID:20012763
  • Banci, L., Bertini, I., Cremonini, M. A., Gori-Savellini, G., Luchinat, C., Wuthrich, K., Guntert, P. Pseudyana for NMR structure calculation of paramagnetic metalloproteins using torsion angle molecular dynamics Journal of Biomolecular NMR  1998 12:553-557  DOI:10.1023/a:1008388614638  PMID:20012764
  • Pellecchia, M., Guntert, P., Glockshuber, R., Wuthrich, K. Sequence-specific h-1, n-15 and c-13 assignments of the periplasmic chaperone fimc from escherichia coli Journal of Biomolecular NMR  1998 11:229-230  DOI:10.1023/a:1008207111214  PMID:9679298
  • Mumenthaler, C., Guntert, P., Braun, W., Wuthrich, K. Automated combined assignment of noesy spectra and three-dimensional protein structure determination Journal of Biomolecular NMR  1997 10:351-362  DOI:10.1023/a:1018383106236  PMID:9460241
  • Bartels, C., Guntert, P., Billeter, M., Wuthrich, K. Garant - a general algorithm for resonance assignment of multidimensional nuclear magnetic resonance spectra Journal of Computational Chemistry  1997 18:139-149  DOI:10.1002/(sici)1096-987x(19970115)18:1<139::aid-jcc13>3.0.co;2-h
  • Ottiger, M., Zerbe, O., Guntert, P., Wuthrich, K. The NMR solution conformation of unligated human cyclophilin A Journal of Molecular Biology  1997 272:64-81  DOI:10.1006/jmbi.1997.1220  PMID:9299338
  • Luginbuhl, P., Guntert, P., Billeter, M., Wuthrich, K. The new program opal for molecular dynamics simulations and energy refinements of biological macromolecules Journal of Biomolecular NMR  1997 9:212-212
  • Guntert, P., Mumenthaler, C., Wuthrich, K. Torsion angle dynamics for NMR structure calculation with the new program dyana Journal of Molecular Biology  1997 273:283-298  DOI:10.1006/jmbi.1997.1284  PMID:9367762
  • Bartels, C., Billeter, M., Guntert, P., Wuthrich, K. Automated sequence-specific NMR assignment of homologous proteins using the program garant Journal of Biomolecular NMR  1996 7:207-213  PMID:22911044
  • Berndt, K. D., Guntert, P., Wuthrich, K. Conformational sampling by NMR solution structures calculated with the program diana evaluated by comparison with long-time molecular dynamics calculations in explicit water Proteins-Structure Function and Genetics  1996 24:304-313  DOI:10.1002/(sici)1097-0134(199603)24:3<304::aid-prot3>3.0.co;2-g  PMID:8778777
  • Billeter, M., Guntert, P., Luginbuhl, P., Wuthrich, K. Hydration and DNA recognition by homeodomains Cell  1996 85:1057-1065  DOI:10.1016/s0092-8674(00)81306-9  PMID:8674112
  • Wuthrich, K., Billeter, M., Guntert, P., Luginbuhl, P., Riek, R., Wider, G. NMR studies of the hydration of biological macromolecules Faraday Discussions  1996 103:245-253  DOI:10.1039/fd9960300245
  • Luginbuhl, P., Guntert, P., Billeter, M., Wuthrich, K. The new program opal for molecular dynamics simulations and energy refinements of biological macromolecules Journal of Biomolecular NMR  1996 8:136-146  PMID:8914272
  • Bartels, C., Guntert, P., Wuthrich, K. Iflat - a new automatic baseline-correction method for multidimensional NMR spectra with strong solvent signals Journal of Magnetic Resonance Series A  1995 117:330-333  DOI:10.1006/jmra.1995.0780
  • Brunne, R. M., Berndt, K. D., Guntert, P., Wuthrich, K., Vangunsteren, W. F. Structure and internal dynamics of the bovine pancreatic trypsin-inhibitor in aqueous-solution from long-time molecular-dynamics simulations Proteins-Structure Function and Genetics  1995 23:49-62  DOI:10.1002/prot.340230107  PMID:8539250
  • Bartels, C., Xia, T. H., Billeter, M., Guntert, P., Wuthrich, K. The program xeasy for computer-supported NMR spectral-analysis of biological macromolecules Journal of Biomolecular NMR  1995 6:1-10  DOI:10.1007/bf00417486  PMID:22911575
  • Antuch, W., Guntert, P., Billeter, M., Hawthorne, T., Grossenbacher, H., Wuthrich, K. Nmr solution structure of the recombinant tick anticoagulant protein (rtap), a factor xa inhibitor from the tick ornithodoros-moubata FEBS Letters  1994 352:251-257  DOI:10.1016/0014-5793(94)00941-4  PMID:7925983
  • Berndt, K. D., Guntert, P., Wuthrich, K. Nuclear-magnetic-resonance solution structure of dendrotoxin-k from the venom of dendroaspis-polylepis-polylepis Journal of Molecular Biology  1993 234:735-750  DOI:10.1006/jmbi.1993.1623  PMID:8254670
  • Guntert, P., Schaefer, N., Otting, G., Wuthrich, K. Poma - a complete mathematica implementation of the NMR product-operator formalism Journal of Magnetic Resonance Series A  1993 101:103-105  DOI:10.1006/jmra.1993.1016
  • Szyperski, T., Luginbuhl, P., Otting, G., Guntert, P., Wuthrich, K. Protein dynamics studied by rotating frame n-15 spin relaxation-times Journal of Biomolecular NMR  1993 3:151-164  PMID:7682879
  • Guntert, P., Berndt, K. D., Wuthrich, K. The program asno for computer-supported collection of noe upper distance constraints as input for protein-structure determination Journal of Biomolecular NMR  1993 3:601-606
  • Berndt, K. D., Guntert, P., Orbons, L. P. M., Wuthrich, K. Determination of a high-quality nuclear-magnetic-resonance solution structure of the bovine pancreatic trypsin-inhibitor and comparison with 3 crystal-structures Journal of Molecular Biology  1992 227:757-775  DOI:10.1016/0022-2836(92)90222-6  PMID:1383552
  • Szyperski, T., Guntert, P., Otting, G., Wuthrich, K. Determination of scalar coupling-constants by inverse fourier transformation of in-phase multiplets Journal of Magnetic Resonance  1992 99:552-560  DOI:10.1016/0022-2364(92)90209-p
  • Guntert, P., Wuthrich, K. Flatt - a new procedure for high-quality base-line correction of multidimensional NMR-spectra Journal of Magnetic Resonance  1992 96:403-407  DOI:10.1016/0022-2364(92)90095-o
  • Szyperski, T., Guntert, P., Stone, S. R., Tulinsky, A., Bode, W., Huber, R., Wuthrich, K. Impact of protein protein contacts on the conformation of thrombin-bound hirudin studied by comparison with the nuclear-magnetic-resonance solution structure of hirudin(1-51) Journal of Molecular Biology  1992 228:1206-1211  DOI:10.1016/0022-2836(92)90326-f  PMID:1474586
  • Szyperski, T., Guntert, P., Stone, S. R., Wuthrich, K. Nuclear-magnetic-resonance solution structure of hirudin(1-51) and comparison with corresponding 3-dimensional structures determined using the complete 65-residue hirudin polypeptide-chain Journal of Molecular Biology  1992 228:1193-1205  DOI:10.1016/0022-2836(92)90325-e  PMID:1335515
  • Guntert, P., Dotsch, V., Wider, G., Wuthrich, K. Processing of multidimensional NMR data with the new software prosa Journal of Biomolecular NMR  1992 2:619-629  DOI:10.1007/bf02192850
  • Guntert, P., Braun, W., Wuthrich, K. Efficient computation of 3-dimensional protein structures in solution from nuclear-magnetic-resonance data using the program diana and the supporting programs caliba, habas and glomsa Journal of Molecular Biology  1991 217:517-530  DOI:10.1016/0022-2836(91)90754-t  PMID:1847217
  • Guntert, P., Qian, Y. Q., Otting, G., Muller, M., Gehring, W., Wuthrich, K. Structure determination of the antp(c39- s) homeodomain from nuclear-magnetic-resonance data in solution using a novel strategy for the structure calculation with the programs diana, caliba, habas and glomsa Journal of Molecular Biology  1991 217:531-540  DOI:10.1016/0022-2836(91)90755-u  PMID:1671604
  • Guntert, P., Braun, W., Billeter, M., Wuthrich, K. Automated stereospecific h-1-NMR assignments and their impact on the precision of protein-structure determinations in solution Journal of the American Chemical Society  1989 111:3997-4004