recent publications

• academic article

  • van Doremalen, N., Miazgowicz, K. L., Milne-Price, S., Bushmaker, T., Robertson, S., Scott, D., Kinne, J., McLellan, J. S., Zhu, J., Munster, V. J. Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4 Journal of Virology  2014 88:9220-9232  DOI:10.1128/jvi.00676-14  PMID:24899185  PMCID:PMC4136254
  • Falzarano, D., de Wit, E., Feldmann, F., Rasmussen, A. L., Okumura, A., Peng, X., Thomas, M. J., van Doremalen, N., Haddock, E., Nagy, L., LaCasse, R., Liu, T., et al. Infection with MERS-CoV causes lethal pneumonia in the common marmoset PLoS Pathogens  2014 10:e1004250  DOI:10.1371/journal.ppat.1004250  PMID:25144235  PMCID:PMC4140844
  • Pancera, M., Yang, Y. P., Louder, M. K., Gorman, J., Lu, G., McLellan, J. S., Stuckey, J., Zhu, J., Burton, D. R., Koff, W. C., Mascola, J. R., Kwong, P. D. N332-directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function PLoS One  2013 8:e55701  DOI:10.1371/journal.pone.0055701  PMID:23431362  PMCID:PMC3576407
  • Pancera, M., Shahzad-ul-Hussan, S., Doria-Rose, N. A., McLellan, J. S., Bailer, R. T., Dai, K., Loesgen, S., Louder, M. K., Staupe, R. P., Yang, Y., Zhang, B., Parks, R., et al. Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16 Nature Structural & Molecular Biology  2013 20:804-813  DOI:10.1038/nsmb.2600  PMID:23708607  PMCID:PMC4046252
  • Amin, M. N., McLellan, J. S., Huang, W., Orwenyo, J., Burton, D. R., Koff, W. C., Kwong, P. D., Wang, L. X. Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies Nature Chemical Biology  2013 9:521-526  DOI:10.1038/nchembio.1288  PMID:23831758  PMCID:PMC3730851
  • Doria-Rose, N. A., Georgiev, I., O'Dell, S., Chuang, G. Y., Staupe, R. P., McLellan, J. S., Gorman, J., Pancera, M., Bonsignori, M., Haynes, B. F., Burton, D. R., Koff, W. C., et al. A short segment of the hiv-1 gp120 v1/v2 region is a major determinant of resistance to v1/v2 neutralizing antibodies Journal of Virology  2012 86:8319-8323  DOI:10.1128/jvi.00696-12  PMID:22623764  PMCID:PMC3421697
  • Rolland, M., Edlefsen, P. T., Larsen, B. B., Tovanabutra, S., Sanders-Buell, E., Hertz, T., deCamp, A. C., Carrico, C., Menis, S., Magaret, C. A., Ahmed, H., Juraska, M., et al. Increased hiv-1 vaccine efficacy against viruses with genetic signatures in env v2 Nature  2012 490:417-20  DOI:10.1038/nature11519  PMID:22960785  PMCID:PMC3551291
  • Azoitei, M. L., Correia, B. E., Ban, Y. E. A., Carrico, C., Kalyuzhniy, O., Chen, L., Schroeter, A., Huang, P. S., McLellan, J. S., Kwong, P. D., Baker, D., Strong, R. K., et al. Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold Science  2011 334:373-376  DOI:10.1126/science.1209368  PMID:22021856
  • McLellan, J. S., Correia, B. E., Chen, M., Yang, Y. P., Graham, B. S., Schief, W. R., Kwong, P. D. Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus Journal of Molecular Biology  2011 409:853-866  DOI:10.1016/j.jmb.2011.04.044  PMID:21549714  PMCID:PMC3107930
  • McLellan, J. S., Pancera, M., Carrico, C., Gorman, J., Julien, J. P., Khayat, R., Louder, R., Pejchal, R., Sastry, M., Dai, K. F., O'Dell, S., Patel, N., et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 Nature  2011 480:336-343  DOI:10.1038/nature10696  PMID:22113616  PMCID:PMC3406929
  • Pancera, M., McLellan, J. S., Wu, X., Zhu, J., Changela, A., Schmidt, S. D., Yang, Y., Zhou, T., Phogat, S., Mascola, J. R., Kwong, P. D. Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1 Journal of Virology  2010 84:8098-8110  DOI:10.1128/jvi.00966-10  PMID:20538861  PMCID:PMC2916520