recent publications

• academic article

  • Yates III, J. R., Kelleher, N. L. Top down proteomics Analytical Chemistry  2013 85:6151  DOI:10.1021/ac401484r  PMID:23705843  PMCID:PMC4418644
  • Zhang, J., Van Lanen, S. G., Ju, J. H., Liu, W., Dorrestein, P. C., Li, W. L., Kelleher, N. L., Shen, B. A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis Proceedings of the National Academy of Sciences of the United States of America  2008 105:1460-1465  DOI:10.1073/pnas.0711625105  PMID:18223152  PMCID:PMC2234166
  • Hwang, Y., Thompson, P. R., Wang, L., Jiang, L., Kelleher, N. L., Cole, P. A. A selective chemical probe for coenzyme a - requiring enzymes Angewandte Chemie-International Edition  2007 46:7621-7624  DOI:10.1002/anie.200702485  PMID:17768748
  • Astle, J., Ferguson, J. T., German, J. B., Harrigan, G. G., Kelleher, N. L., Kodadek, T., Parks, B. A., Roth, M. J., Singletary, K. W., Wenger, C. D., Mahady, G. B. Characterization of proteomic and metabolomic responses to dietary factors and supplements Journal of Nutrition  2007 137:2787-2793  PMID:18029500
  • Van Lanen, S. G., Lin, S. J., Dorrestein, P. C., Kelleher, N. L., Shen, B. Substrate specificity of the adenylation enzyme sgcc1 involved in the biosynthesis of the enediyne antitumor antibiotic c-1027 Journal of Biological Chemistry  2006 281:29633-29640  DOI:10.1074/jbc.M605887200  PMID:16887797
  • Dorrestein, P. C., Van Lanen, S. G., Li, W. L., Zhao, C. H., Deng, Z. X., Shen, B., Kelleher, N. L. The bifunctional glyceryl transferase/phosphatase ozmb belonging to the had superfamily that diverts 1,3-bisphosphoglycerate into polyketide biosynthesis Journal of the American Chemical Society  2006 128:10386-10387  DOI:10.1021/ja0639362  PMID:16895402
  • Van Lanen, S. G., Dorrestein, P. C., Christenson, S. D., Liu, W., Ju, J. H., Kelleher, N. L., Shen, B. Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic c-1027 featuring beta-amino acyl-s-carrier protein intermediates Journal of the American Chemical Society  2005 127:11594-11595  DOI:10.1021/ja052871k  PMID:16104723