recent publications

• academic article

  • Boger, D. L., Santillan, A., Searcey, M., Brunette, S. R., Wolkenberg, S. E., Hedrick, M. P., Jin, Q. Synthesis and evaluation of 1,2,8, 8a-Tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: impact of the alkylation subunit substituents and its implications for DNA alkylation catalysis Journal of Organic Chemistry  2000 65:4101-4111  DOI:10.1021/jo000297j  PMID:10866627
  • Boger, D. L., Santillan, A., Searcey, M., Jin, Q. Synthesis and evaluation of duocarmycin and CC-1065 analogues containing modifications in the subunit linking amide Journal of Organic Chemistry  1999 64:5241-5244  DOI:10.1021/jo990452y
  • Boger, D. L., Santillan, A., Searcey, M., Jin, Q. Critical role of the linking amide in CC-1065 and the duocarmycins: implications on the source of DNA alkylation catalysis Journal of the American Chemical Society  1998 120:11554-11557  DOI:10.1021/ja9818093