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Total synthesis of tovophyllin b

Academic Article
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Overview

related to degree

  • Jeso, Valer, Ph.D. in Chemistry, Scripps Research 2003 - 2008

authors

  • Jeso, Valer
  • Nicolaou, K.C.

publication date

  • March 2009

journal

  • Tetrahedron Letters  Journal

abstract

  • The first total synthesis of tovophyllin B (2), an antimicrobial xanthone derived from mangosteen, has been accomplished through a convergent strategy from building blocks 6 and 7 involving lithium-mediated coupling, dehydrative cyclization, and 6π electrocyclization as key steps.
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Identity

PubMed Central ID

  • PMC2683023

International Standard Serial Number (ISSN)

  • 0040-4039

Digital Object Identifier (DOI)

  • 10.1016/j.tetlet.2008.12.096

PubMed ID

  • 20161287
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Additional Document Info

start page

  • 1161

end page

  • 1163

volume

  • 50

issue

  • 11

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