Prodrug activation gated by a molecular "or" logic trigger

Academic Article

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• Research
• Identity
• Additional Document Info
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Overview

authors

• Amir, R. J.
• Popkov, M.
• Lerner, Richard
• Barbas III, Carlos
• Shabat, Doron

publication date

• 2005

journal

• Angewandte Chemie-International Edition  Journal

subject areas

• Antibiotics, Antineoplastic
• Cell Line, Tumor
• Cell Proliferation
• Chromatography, High Pressure Liquid
• Doxorubicin
• Drug Screening Assays, Antitumor
• Fructose-Bisphosphate Aldolase
• Humans
• Immunoglobulin Fab Fragments
• Logic
• Models, Biological
• Penicillin Amidase
• Prodrugs

Research

keywords

• catalytic antibodies
• drug delivery
• enzymes
• logic gates
• prodrugs

Identity

International Standard Serial Number (ISSN)

• 1433-7851

Digital Object Identifier (DOI)

• 10.1002/anie.200500842

PubMed ID

• 15942963

Additional Document Info

start page

• 4378

end page

• 4381

volume

• 44

issue

• 28