recent publications

• academic article

  • He, W., Scharadin, T. M., Saldana, M., Gellner, C., Hoang-Phou, S., Takanishi, C., Hura, G. L., Tainer, J. A., Carraway III, K. L., Henderson, P. T., Coleman, M. A. Cell-free expression of functional receptor tyrosine kinases Scientific Reports  2015 5:012896  DOI:10.1038/srep12896  PMID:26274523  PMCID:PMC4929682
  • Lai, Y. T., Reading, E., Hura, G. L., Tsai, K. L., Laganowsky, A., Asturias, F. J., Tainer, J. A., Robinson, C. V., Yeates, T. O. Structure of a designed protein cage that self-assembles into a highly porous cube Nature Chemistry  2014 6:1065-1071  DOI:10.1038/nchem.2107  PMID:25411884  PMCID:PMC4239666
  • Hura, G. L., Budworth, H., Dyer, K. N., Rambo, R. P., Hammel, M., McMurray, C. T., Tainer, J. A. Comprehensive macromolecular conformations mapped by quantitative SAXS analyses Nature Methods  2013 10:453-454  DOI:10.1038/nmeth.2453  PMID:23624664  PMCID:PMC3728378
  • Hura, G. L., Tsai, C. L., Claridge, S. A., Mendillo, M. L., Smith, J. M., Williams, G. J., Mastroianni, A. J., Alivisatos, A. P., Putnam, C. D., Kolodner, R. D., Tainer, J. A. DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals Proceedings of the National Academy of Sciences of the United States of America  2013 110:17308-17313  DOI:10.1073/pnas.1308595110  PMID:24101514  PMCID:PMC3808630
  • Classen, S., Hura, G. L., Holton, J. M., Rambo, R. P., Rodic, I., McGuire, P. J., Dyer, K., Hammel, M., Meigs, G., Frankel, K. A., Tainer, J. A. Implementation and performance of SIBYLS: A dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source Journal of Applied Crystallography  2013 46:1-13  DOI:10.1107/s0021889812048698  PMID:23396808  PMCID:PMC3547225
  • Hammel, M., Yu, Y. P., Mahaney, B. L., Cai, B., Ye, R. Q., Phipps, B. M., Rambo, R. P., Hura, G. L., Pelikan, M., So, S., Abolfath, R. M., Chen, D. J., et al. Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex Journal of Biological Chemistry  2010 285:1414-1423  DOI:10.1074/jbc.M109.065615  PMID:19893054  PMCID:PMC2801267
  • Classen, S., Rodic, I., Holton, J., Hura, G. L., Hammel, M., Tainer, J. A. Software for the high-throughput collection of saxs data using an enhanced blu-ice/dcs control system Journal of Synchrotron Radiation  2010 17:774-781  DOI:10.1107/s0909049510028566  PMID:20975223  PMCID:PMC2964114
  • Aleshin, A. E., Gramatikova, S., Hura, G. L., Bobkov, A., Strongin, A. Y., Stec, B., Tainer, J. A., Liddington, R. C., Smith, J. W. Crystal and solution structures of a prokaryotic m16b peptidase: An open and shut case Structure  2009 17:1465-1475  DOI:10.1016/j.str.2009.09.009  PMID:19913481  PMCID:PMC3615642
  • Hura, G. L., Menon, A. L., Hammel, M., Rambo, R. P., Poole, F. L., 2nd, Tsutakawa, S. E., Jenney, F. E., Jr., Classen, S., Frankel, K. A., Hopkins, R. C., Yang, S. J., Scott, J. W., et al. Robust, high-throughput solution structural analyses by small angle x-ray scattering (saxs) Nature Methods  2009 6:606-612  DOI:10.1038/nmeth.1353  PMID:19620974  PMCID:PMC3094553
  • Shin, D. S., DiDonato, M., Barondeau, D. P., Hura, G. L., Hitomi, C., Berglund, J. A., Getzoff, E. D., Cary, S. C., Tainer, J. A. Superoxide dismutase from the eukaryotic thermophile alvinella pompejana: Structures, stability, mechanism, and insights into amyotrophic lateral sclerosis Journal of Molecular Biology  2009 385:1534-1555  DOI:10.1016/j.jmb.2008.11.031  PMID:19063897  PMCID:PMC2669833
  • Chrencik, J. E., Brooun, A., Zhang, H., Mathews, II, Hura, G. L., Foster, S. A., Perry, J. J. P., Streiff, M., Ramage, P., Widmer, H., Bokoch, G. M., Tainer, J. A., et al. Structural basis of guanine nucleotide exchange mediated by the t-cell essential vav1 Journal of Molecular Biology  2008 380:828-843  DOI:10.1016/j.jmb.2008.05.024  PMID:18589439  PMCID:PMC2620086
  • Tsutakawa, S. E., Hura, G. L., Frankel, K. A., Cooper, P. K., Tainer, J. A. Structural analysis of flexible proteins in solution by small angle x-ray scattering combined with crystallography Journal of Structural Biology  2007 158:214-223  DOI:10.1016/j.jsb.2006.09.008  PMID:17182256
  • Putnam, C. D., Hammel, M., Hura, G. L., Tainer, J. A. X-ray solution scattering (saxs) combined with crystallography and computation: Defining accurate macromolecular structures, conformations and assemblies in solution Quarterly Reviews of Biophysics  2007 40:191-285  DOI:10.1017/s0033583507004635  PMID:18078545
  • Pascal, J. M., Tsodikov, O. V., Hura, G. L., Song, W., Cotner, E. A., Classen, S., Tomkinson, A. E., Tainer, J. A., Ellenberger, T. A flexible interface between DNA ligase and pcna supports conformational switching and efficient ligation of DNA Molecular Cell  2006 24:279-291  DOI:10.1016/j.molcel.2006.08.015  PMID:17052461