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Developing soluble polymers for high-throughput synthetic chemistry

Academic Article
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Overview

authors

  • Spanka, C.
  • Wentworth Jr., Paul
  • Janda, Kim

publication date

  • May 2002

journal

  • Combinatorial Chemistry & High Throughput Screening  Journal

abstract

  • Soluble polymers have emerged as viable alternatives to resin supports across the broad spectrum of high-throughput organic chemistry. As the application of these supports become more widespread, issues such as broad-spectrum solubility and loading are becoming limiting factors and therefore new polymers are required to overcome such limitations. This article details the approach made within our group to new soluble polymer supports and specifically focuses on parallel libraries of block copolymers, de novo poly(styrene-co-chloromethylstyrene), PEG- stealth stars, and substituted poly(norbornylene)s.

subject areas

  • Combinatorial Chemistry Techniques
  • Indicators and Reagents
  • Magnetic Resonance Spectroscopy
  • Molecular Weight
  • Norbornanes
  • Polymers
  • Resins, Plant
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Spectrophotometry, Infrared
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Identity

International Standard Serial Number (ISSN)

  • 1386-2073

PubMed ID

  • 11966431
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Additional Document Info

start page

  • 233

end page

  • 240

volume

  • 5

issue

  • 3

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