recent publications

• academic article

  • Chen, C. H., Schork, A. J., Lo, M. T., Fan, C. C., Wang, Y., Desikan, R. S., Bettella, F., Hagler, D. J., Pediatric Imaging, Neurocognition, Alzheimer's Disease Neuroimaging Initiative, Westlye, L. T., Kremen, W. S. Large-scale genomics unveil polygenic architecture of human cortical surface area Nature Communications  2015 6:7549  DOI:10.1038/ncomms8549  PMID:26189703  PMCID:PMC4518289
  • Boraska, V., Franklin, C. S., Floyd, J. A. B., Thornton, L. M., Huckins, L. M., Southam, L., Rayner, N. W., Tachmazidou, I., Klump, K. L., Treasure, J., Lewis, C. M., Schmidt, U., et al. A genome-wide association study of anorexia nervosa Molecular Psychiatry  2014 19:1085-1094  DOI:10.1038/mp.2013.187  PMID:24514567  PMCID:PMC4325090
  • Schork, A. J., Thompson, W. K., Pham, P., Torkamani, A., Roddey, J. C., Sullivan, P. F., Kelsoe, J. R., O'Donovan, M. C., Furberg, H., The Tobacco & Genetics Consortium, The Bipolar Disorder Psychiatric Genomics Consortium, Schizophrenia Psychiatric Genomics Consortium, et al. All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs PLoS Genetics  2013 9:e1003449  DOI:10.1371/journal.pgen.1003449  PMID:23637621  PMCID:PMC3636284
  • Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs Nature Genetics  2013 45:984-994  DOI:10.1038/ng.2711  PMID:23933821  PMCID:PMC3800159
  • Carlstrom, E. L., Saetre, P., Rosengren, A., Thygesen, J. H., Djurovic, S., Melle, I., Andreassen, O. A., Werge, T., Agartz, I., Hall, H., Terenius, L., Jonsson, E. G. Association between a genetic variant in the serotonin transporter gene (slc6a4) and suicidal behavior in patients with schizophrenia Behavioral and Brain Functions  2012 8:24  DOI:10.1186/1744-9081-8-24  PMID:22594806  PMCID:PMC3527134
  • Bakken, T. E., Roddey, J. C., Djurovic, S., Akshoomoff, N., Amaral, D. G., Bloss, C. S., Casey, B. J., Chang, L., Ernst, T. M., Gruen, J. R., Jernigan, T. L., Kaufmann, W. E., et al. Association of common genetic variants in gpcpd1 with scaling of visual cortical surface area in humans Proceedings of the National Academy of Sciences of the United States of America  2012 109:3985-3990  DOI:10.1073/pnas.1105829109  PMID:22343285  PMCID:PMC3309762
  • Andreou, D., Saetre, P., Werge, T., Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L., Jonsson, E. G. D-amino acid oxidase activator gene (daoa) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy caucasians European Archives of Psychiatry and Clinical Neuroscience  2012 262:549-556  DOI:10.1007/s00406-012-0313-z  PMID:22454242  PMCID:PMC3464385
  • Holtze, M., Saetre, P., Engberg, G., Schwieler, L., Werge, T., Andreassen, O. A., Hall, H., Terenius, L., Agartz, I., Jonsson, E. G., Schalling, M., Erhardt, S. Kynurenine 3-monooxygenase polymorphisms: Relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls Journal of Psychiatry and Neuroscience  2012 37:53-57  DOI:10.1503/jpn.100175  PMID:21693093  PMCID:PMC3244499
  • Saetre, P., Grove, J., Borglum, A. D., Mors, O., Werge, T., Andreassen, O. A., Vares, M., Agartz, I., Terenius, L., Jonsson, E. G. Methylenetetrahydrofolate reductase (mthfr) c677t polymorphism and age at onset of schizophrenia: No consistent evidence for an association in the nordic population American Journal of Medical Genetics Part B-Neuropsychiatric Genetics  2012 159B:981-986  DOI:10.1002/ajmg.b.32104  PMID:23076983  PMCID:PMC3739001
  • Bakken, T. E., Bloss, C. S., Roddey, J. C., Joyner, A. H., Rimol, L. M., Djurovic, S., Melle, I., Sundet, K., Agartz, I., Andreassen, O. A., Dale, A. M., Schork, N. J. Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia Archives of General Psychiatry  2011 68:781-790  DOI:10.1001/archgenpsychiatry.2011.81  PMID:21810643  PMCID:PMC3375053
  • Steinberg, S., de Jong, S., Andreassen, O. A., Werge, T., Borglum, A. D., Mors, O., Mortensen, P. B., Gustafsson, O., Costas, J., Pietilainen, O. P. H., Demontis, D., Papiol, S., et al. Common variants at VRK(2) and TCF(4) conferring risk of schizophrenia Human Molecular Genetics  2011 20:4076-4081  DOI:10.1093/hmg/ddr325  PMID:21791550  PMCID:PMC3298077
  • Andreou, D., Saetre, P., Kahler, A. K., Werge, T., Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L., Jonsson, E. G. Dystrobrevin-binding protein 1 gene (dtnbp1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers European Neuropsychopharmacology  2011 21:700-704  DOI:10.1016/j.euroneuro.2010.12.008  PMID:21295953
  • Steinberg, S., Mors, O., Borglum, A. D., Gustafsson, O., Werge, T., Mortensen, P. B., Andreassen, O. A., Sigurdsson, E., Thorgeirsson, T. E., Bottcher, Y., Olason, P., Ophoff, R. A., et al. Expanding the range of ZNF804A variants conferring risk of psychosis Molecular Psychiatry  2011 16:59-66  DOI:10.1038/mp.2009.149  PMID:20048749  PMCID:PMC3242031
  • Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D. Y., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., et al. Genome-wide association study identifies five new schizophrenia loci Nature Genetics  2011 43:969-76  DOI:10.1038/ng.940  PMID:21926974  PMCID:PMC3303194
  • Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., Blackwood, D., Corvin, A., Flickinger, M., et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near odz4 Nature Genetics  2011 43:977-983  DOI:10.1038/ng.943  PMID:21926972  PMCID:PMC3637176
  • Saetre, P., Vares, M., Werge, T., Andreassen, O. A., Arinami, T., Ishiguro, H., Nanko, S., Tan, E. C., Han, D. H., Roffman, J. L., Muntjewerff, J. W., Jagodzinski, P. P., et al. Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples American Journal of Medical Genetics Part B-Neuropsychiatric Genetics  2011 156B:215-224  DOI:10.1002/ajmg.b.31160  PMID:21302350
  • Vares, M., Saetre, P., Deng, H., Cai, G. Q., Liu, X. H., Hansen, T., Rasmussen, H. B., Werge, T., Melle, I., Djurovic, S., Andreassen, O. A., Agartz, I., et al. Association between methylenetetrahydrofolate reductase (mthfr) c677t polymorphism and age of onset in schizophrenia American Journal of Medical Genetics Part B-Neuropsychiatric Genetics  2010 153B:610-618  DOI:10.1002/ajmg.b.31030  PMID:19746410
  • Rimol, L. M., Agartz, I., Djurovic, S., Brown, A. A., Roddey, J. C., Kahler, A. K., Mattingsdal, M., Athanasiu, L., Joyner, A. H., Schork, N. J., Halgren, E., Sundet, K., et al. Sex-dependent association of common variants of microcephaly genes with brain structure Proceedings of the National Academy of Sciences of the United States of America  2010 107:384-388  DOI:10.1073/pnas.0908454107  PMID:20080800  PMCID:PMC2806758
  • Saetre, P., Lundmark, P., Wang, A., Hansen, T., Rasmussen, H. B., Djurovic, S., Melle, I., Andreassen, O. A., Werge, T., Agartz, I., Hall, H., Terenius, L., et al. The tryptophan hydroxylase 1 (tph1) gene, schizophrenia susceptibility, and suicidal behavior: A multi-centre case-control study and meta-analysis American Journal of Medical Genetics Part B-Neuropsychiatric Genetics  2010 153B:387-396  DOI:10.1002/ajmg.b.30991  PMID:19526457
  • Andreou, D., Saetre, P., Werge, T., Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L., Jonsson, E. G. Tryptophan hydroxylase gene 1 (tph1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers Psychiatry Research  2010 180:63-67  DOI:10.1016/j.psychres.2009.11.018  PMID:20580984
  • Joyner, A. H., Roddey, J. C., Bloss, C. S., Bakken, T. E., Rimol, L. M., Melle, I., Agartz, I., Djurovic, S., Topol, E. J., Schork, N. J., Andreassen, O. A., Dale, A. M. A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations Proceedings of the National Academy of Sciences of the United States of America  2009 106:15483-15488  DOI:10.1073/pnas.0901866106  PMID:19717458  PMCID:PMC2741277
  • Stefansson, H., Ophoff, R. A., Steinberg, S., Andreassen, O. A., Cichon, S., Rujescu, D., Werge, T., Pietilainen, O. P. H., Mors, O., Mortensen, P. B., Sigurdsson, E., Gustafsson, O., et al. Common variants conferring risk of schizophrenia Nature  2009 460:744-7  DOI:10.1038/nature08186  PMID:19571808  PMCID:PMC3077530
  • Jonsson, E. G., Saetre, P., Vares, M., Andreou, D., Larsson, K., Timm, S., Rasmussen, H. B., Djurovic, S., Melle, I., Andreassen, O. A., Agartz, I., Werge, T., et al. Dtnbp1, nrg1, daoa, dao and grm3 polymorphisms and schizophrenia: An association study Neuropsychobiology  2009 59:142-150  DOI:10.1159/000218076  PMID:19439994
  • Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S., Andreassen, O. A., Werge, T., Hall, H., Agartz, I., Terenius, L., et al. Tyrosine hydroxylase val81met polymorphism: Lack of association with schizophrenia Psychiatric Genetics  2009 19:273-274  DOI:10.1097/YPG.0b013e32832a4fcd  PMID:19491717
  • Saetre, P., Agartz, I., De Franciscis, A., Lundmark, P., Djurovic, S., Kahler, A., Andreassen, O. A., Jakobsen, K. D., Rasmussen, H. B., Werge, T., Hall, H., Terenius, L., et al. Association between a disrupted-in-schizophrenia 1 (disc1) single nucleotide polymorphism and schizophrenia in a combined scandinavian case-control sample Schizophrenia Research  2008 106:237-241  DOI:10.1016/j.schres.2008.08.024  PMID:18818052
  • Jonsson, E. G., Larsson, K., Vares, M., Hansen, T., Wang, A. G., DjuroviC, S., Ronningen, K. S., Andreassen, O. A., Agartz, I., Werge, T., Terenius, L., Hall, H. Two methylenetetrahydrofolate reductase gene (mthfr) polymorphisms, schizophrenia and bipolar disorder: An association study American Journal of Medical Genetics Part B-Neuropsychiatric Genetics  2008 147B:976-982  DOI:10.1002/ajmg.b.30671  PMID:18165967