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Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease

Academic Article
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Overview

authors

  • Silhar, P.
  • Alakurtti, S.
  • Caapkova, K.
  • Feng, X. C.
  • Shoemaker, C. B.
  • Yli-Kauhaluoma, J.
  • Janda, Kim

publication date

  • April 2011

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Animals
  • Botulinum Toxins
  • Botulinum Toxins, Type A
  • Neurons
  • Protease Inhibitors
  • Rats
  • Small Molecule Libraries
  • Structure-Activity Relationship
  • Succinates
  • Triterpenes
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Research

keywords

  • Betulin derivatives
  • Botulinum neurotoxin
  • Protease inhibitor
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Identity

PubMed Central ID

  • PMC3070790

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2011.02.115

PubMed ID

  • 21421315
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Additional Document Info

start page

  • 2229

end page

  • 2231

volume

  • 21

issue

  • 8

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