recent publications

• academic article

  • Saw, J., Bhatt, D. L., Moliterno, D. J., Brener, S. J., Steinhubl, S. R., Lincoff, A. M., Tcheng, J. E., Harrington, R. A., Simoons, M., Hu, T., Sheikh, M. A., Kereiakes, D. J., et al. The influence of peripheral arterial disease on outcomes - a pooled analysis of mortality in eight large randomized percutaneous coronary intervention trials Journal of the American College of Cardiology  2006 48:1567-1572  DOI:10.1016/j.jacc.2006.03.067  PMID:17045889
  • Grines, C., Patel, A., Zijlstra, F., Weaver, W. D., Granger, C., Simes, R. J., Ellis, S., Betriu, A., Garcia, E., Grinfeld, L., Gibbons, R., Ribeiro, E., et al. Primary coronary angioplasty compared with intravenous thrombolytic therapy for acute myocardial infarction: Six-month follow up and analysis of individual patient data from randomized trials American Heart Journal  2003 145:47-57  DOI:10.1067/mhj.2003.40  PMID:12514654
  • Topol, E. J., Califf, R. M., Van de Werf, F., Willerson, J. T., Booth, J., White, H., Clayman, M., Deckelbaum, L., Lincoff, A. M., Ohman, E. M., Bates, E., Gibler, W. B., et al. Reperfusion therapy for acute myocardial infarction with fibrinolytic therapy or combination reduced fibrinolytic therapy and platelet glycoprotein iib/iiia inhibition: The gusto randomised trial Lancet  2001 357:1905-1914  PMID:11425410
  • Hasdai, D., Holmes, D. R., Criger, D. A., Topol, E. J., Califf, R. M., Wilcox, R. G., Paolasso, E., Simoons, M., Deckers, J., Harrington, R. A., investigators, Pursuit trial Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent st-segment elevation: Effect of inhibition of platelet glycoprotein iib/iiia with eptifibatide American Heart Journal  2000 139:454-460  DOI:10.1067/mhj.2000.103847  PMID:10689260
  • McClure, M. W., Berkowitz, S. D., Sparapani, R., Tuttle, R., Kleiman, N. S., Berdan, L. G., Lincoff, A. M., Deckers, J., Diaz, R., Karsch, K. R., Gretler, D., Kitt, M., et al. Clinical significance of thrombocytopenia during a non-st-elevation acute coronary syndrome - the platelet glycoprotein iib iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial experience Circulation  1999 99:2892-2900  PMID:10359733
  • Topol, E., Califf, R., Simoons, M., Diaz, R., Paolasso, E., Klein, W., Boland, J., DeBacker, G., Armstrong, P., Corbalan, R., Isaza, D., Widimsky, P., et al. Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes New England Journal of Medicine  1998 339:436-443  PMID:9705684
  • Berkowitz, S. D., Granger, C. B., Peiper, K. S., Lee, K. L., Gore, J. M., Simoons, M., Armstrong, P. W., Topol, E. J., Califf, R. M. Incidence and predictors of bleeding after contemporary thrombolytic therapy for myocardial infarction Circulation  1997 95:2508-2516  PMID:9184581
  • Topol, E. J., Califf, R. M., VandeWerf, F., Simoons, M., Hampton, J., Lee, K. L., White, H., Simes, J., Armstrong, P. W. Perspectives on large-scale cardiovascular clinical trials for the new millennium Circulation  1997 95:1072-1082  PMID:9054772
  • Betriu, A., Phillips, H., Ellis, S., Topol, E., Califf, R., VanderWerf, F., Ardissino, D., Armstrong, P. W., Aylward, P., Bates, E., Beatt, K., Cheseboro, J., et al. A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute myocardial infarction New England Journal of Medicine  1997 336:1621-1628  PMID:9173270
  • Topol, E. J., Califf, R., Granger, C., VandeWerf, F., Aylward, P., Simes, J., Col, J., Armstrong, P., Vahanian, A., Neuhaus, K., Rutsch, W., Ardissino, D., et al. A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes New England Journal of Medicine  1996 335:775-782  DOI:10.1056/NEJM199609123351103  PMID:8778585
  • Lee, K. L., Woodlief, L. H., Topol, E. J., Weaver, W. D., Betriu, A., Col, J., Simoons, M., Aylward, P., Vandewerf, F., Califf, R. M. Predictors of 30-day mortality in the era of reperfusion for acute myocardial-infarction - results from an international trial of 41 021 patients Circulation  1995 91:1659-1668  PMID:7882472
  • Topol, E., Califf, R., Vandewerf, F., Ardissino, D., Armstrong, P., Aylward, P., Barbash, G., Bates, E., Beatt, K., Betriu, A., Chesebro, J., Col, J., et al. Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes Circulation  1994 90:1631-1637  PMID:7923645
  • Topol, E., Califf, R., Vandewerf, F., Armstrong, P. W., Aylward, P., Barbash, G., Bates, E., Betriu, A., Boissel, J. P., Chesebro, J., Col, J., Debono, D., et al. An international randomized trial comparing 4 thrombolytic strategies for acute myocardial-infarction New England Journal of Medicine  1993 329:673-682  PMID:8204123
  • Topol, E. J., Armstrong, P., Vandewerf, F., Kleiman, N., Lee, K., Morris, D., Simoons, M., Barbash, G., White, H., Califf, R. M. Confronting the issues of patient safety and investigator conflict-of-interest in an international clinical-trial of myocardial reperfusion Journal of the American College of Cardiology  1992 19:1123-1128  PMID:1564212