recent publications

• academic article

  • Moon, E., Han, J. E., Jeon, S., Ryu, J. H., Choi, J. W., Chun, J. Exogenous S1P exposure potentiates ischemic stroke damage that is reduced possibly by inhibiting S1P receptor signaling Mediators of Inflammation  2015 492659  DOI:10.1155/2015/492659  PMID:26576074  PMCID:PMC4630407
  • Kim, D. G., Lee, J. Y., Kwon, N. H., Fang, P., Zhang, Q., Wang, J., Young, N. L., Guo, M., Cho, H. Y., Mushtaq, A. U., Jeon, Y. H., Choi, J. W., et al. Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction Nature Chemical Biology  2014 10:29-34  DOI:10.1038/nchembio.1381  PMID:24212136  PMCID:PMC4021855
  • Anliker, B., Choi, J. W., Lin, M. E., Gardell, S. E., Rivera, R. R., Kennedy, G., Chun, J. Lysophosphatidic acid (LPA) and its receptor, LPA1 , influence embryonic schwann cell migration, myelination, and cell-to-axon segregation Glia  2013 61:2009-2022  DOI:10.1002/glia.22572  PMID:24115248  PMCID:PMC3941654
  • Choi, J. W., Chun, J. Lysophospholipids and their receptors in the central nervous system Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids  2013 1831:20-32  DOI:10.1016/j.bbalip.2012.07.015  PMID:22884303  PMCID:PMC3693945
  • Yung, Y. C., Mutoh, T., Lin, M. E., Noguchi, K., Rivera, R. R., Choi, J. W., Kingsbury, M. A., Chun, J. Lysophosphatidic acid signaling may initiate fetal hydrocephalus Science Translational Medicine  2011 3:99ra87  DOI:10.1126/scitranslmed.3002095  PMID:21900594  PMCID:PMC3653407
  • Choi, J. W., Gardell, S. E., Herr, D. R., Rivera, R., Lee, C. W., Noguchi, K., Teo, S. T., Yung, Y. C., Lu, M., Kennedy, G., Chun, J. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation Proceedings of the National Academy of Sciences of the United States of America  2011 108:751-756  DOI:10.1073/pnas.1014154108  PMID:21177428  PMCID:PMC3021041
  • Lee, C. W., Choi, J. W., Chun, J. Neurological S1P signaling as an emerging mechanism of action of oral FTY720 (fingolimod) in multiple sclerosis Archives of Pharmacal Research  2010 33:1567-1574  DOI:10.1007/s12272-010-1008-5  PMID:21052934
  • Choi, J. W., Herr, D. R., Noguchi, K., Yung, Y. C., Lee, C. W., Mutoh, T., Lin, M. E., Teo, S. T., Park, K. E., Mosley, A. N., Chun, J. LPA receptors: subtypes and biological actions Annual Review of Pharmacology and Toxicology  2010 50:157-186  DOI:10.1146/annurev.pharmtox.010909.105753  PMID:20055701
  • Choi, J. W., Lee, C. W., Chun, J. Biological roles of lysophospholipid receptors revealed by genetic null mice: An update Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids  2008 1781:531-539  DOI:10.1016/j.bbalip.2008.03.004  PMID:18407842  PMCID:PMC2657083
  • Lim, S., Choi, J. W., Kim, H. S., Kim, Y. H., Yea, K., Heo, K., Kim, J. H., Kim, S. H., Song, M., Kim II, J., Ryu, S. H., Suh, P. G. A myristoylated pseudosubstrate peptide of PKC-ζ induces degranulation in HMC-1 cells independently of PKC-ζ activity Life Sciences  2008 82:733-740  DOI:10.1016/j.lfs.2008.01.005  PMID:18289606
  • Spohr, Tcdse, Choi, J. W., Gardell, S. E., Herr, D. R., Rehen, S. K., Gomes, F. C. A., Chun, J. Lysophosphatidic acid receptor-dependent secondary effects via astrocytes promote neuronal differentiation Journal of Biological Chemistry  2008 283:7470-7479  DOI:10.1074/jbc.M707758200  PMID:18198181  PMCID:PMC2276323