recent publications
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academic article
- Moon, E., Han, J. E., Jeon, S., Ryu, J. H., Choi, J. W., Chun, J. Exogenous S1P exposure potentiates ischemic stroke damage that is reduced possibly by inhibiting S1P receptor signaling Mediators of Inflammation 2015 492659 DOI:10.1155/2015/492659 PMID:26576074 PMCID:PMC4630407
- Kim, D. G., Lee, J. Y., Kwon, N. H., Fang, P., Zhang, Q., Wang, J., Young, N. L., Guo, M., Cho, H. Y., Mushtaq, A. U., Jeon, Y. H., Choi, J. W., et al. Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction Nature Chemical Biology 2014 10:29-34 DOI:10.1038/nchembio.1381 PMID:24212136 PMCID:PMC4021855
- Anliker, B., Choi, J. W., Lin, M. E., Gardell, S. E., Rivera, R. R., Kennedy, G., Chun, J. Lysophosphatidic acid (LPA) and its receptor, LPA1 , influence embryonic schwann cell migration, myelination, and cell-to-axon segregation Glia 2013 61:2009-2022 DOI:10.1002/glia.22572 PMID:24115248 PMCID:PMC3941654
- Choi, J. W., Chun, J. Lysophospholipids and their receptors in the central nervous system Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids 2013 1831:20-32 DOI:10.1016/j.bbalip.2012.07.015 PMID:22884303 PMCID:PMC3693945
- Yung, Y. C., Mutoh, T., Lin, M. E., Noguchi, K., Rivera, R. R., Choi, J. W., Kingsbury, M. A., Chun, J. Lysophosphatidic acid signaling may initiate fetal hydrocephalus Science Translational Medicine 2011 3:99ra87 DOI:10.1126/scitranslmed.3002095 PMID:21900594 PMCID:PMC3653407
- Choi, J. W., Gardell, S. E., Herr, D. R., Rivera, R., Lee, C. W., Noguchi, K., Teo, S. T., Yung, Y. C., Lu, M., Kennedy, G., Chun, J. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation Proceedings of the National Academy of Sciences of the United States of America 2011 108:751-756 DOI:10.1073/pnas.1014154108 PMID:21177428 PMCID:PMC3021041
- Lee, C. W., Choi, J. W., Chun, J. Neurological S1P signaling as an emerging mechanism of action of oral FTY720 (fingolimod) in multiple sclerosis Archives of Pharmacal Research 2010 33:1567-1574 DOI:10.1007/s12272-010-1008-5 PMID:21052934
- Choi, J. W., Herr, D. R., Noguchi, K., Yung, Y. C., Lee, C. W., Mutoh, T., Lin, M. E., Teo, S. T., Park, K. E., Mosley, A. N., Chun, J. LPA receptors: subtypes and biological actions Annual Review of Pharmacology and Toxicology 2010 50:157-186 DOI:10.1146/annurev.pharmtox.010909.105753 PMID:20055701
- Choi, J. W., Lee, C. W., Chun, J. Biological roles of lysophospholipid receptors revealed by genetic null mice: An update Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids 2008 1781:531-539 DOI:10.1016/j.bbalip.2008.03.004 PMID:18407842 PMCID:PMC2657083
- Lim, S., Choi, J. W., Kim, H. S., Kim, Y. H., Yea, K., Heo, K., Kim, J. H., Kim, S. H., Song, M., Kim II, J., Ryu, S. H., Suh, P. G. A myristoylated pseudosubstrate peptide of PKC-ζ induces degranulation in HMC-1 cells independently of PKC-ζ activity Life Sciences 2008 82:733-740 DOI:10.1016/j.lfs.2008.01.005 PMID:18289606
- Spohr, Tcdse, Choi, J. W., Gardell, S. E., Herr, D. R., Rehen, S. K., Gomes, F. C. A., Chun, J. Lysophosphatidic acid receptor-dependent secondary effects via astrocytes promote neuronal differentiation Journal of Biological Chemistry 2008 283:7470-7479 DOI:10.1074/jbc.M707758200 PMID:18198181 PMCID:PMC2276323