recent publications

• academic article

  • Handa, M., Scheidt, K. A., Bossart, M., Zheng, N., Roush, W. R. Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment Journal of Organic Chemistry  2008 73:1031-1035  DOI:10.1021/jo702250z  PMID:18163645
  • Scheidt, K. A., Bannister, T. D., Tasaka, A., Wendt, M. D., Savall, B. M., Fegley, G. J., Roush, W. R. Total synthesis of (-)-bafilomycin A(1) Journal of the American Chemical Society  2002 124:6981-6990  DOI:10.1021/ja017885e  PMID:12059221
  • Roush, W. R., Bannister, T. D., Wendt, M. D., VanNieuwenhze, M. S., Gustin, D. J., Dilley, G. J., Lane, G. C., Scheidt, K. A., Smith, W. J. An NMR method for assigning relative stereochemistry to beta-hydroxy ketones deriving from aldol reactions of methyl ketones Journal of Organic Chemistry  2002 67:4284-4289  DOI:10.1021/jo0164148  PMID:12054964
  • Roush, W. R., Bannister, T. D., Wendt, M. D., Jablonowski, J. A., Scheidt, K. A. Studies on the synthesis of bafilomycin A(1): stereochemical aspects of the fragment assembly aldol reaction for construction of the C(13)-C25) segment Journal of Organic Chemistry  2002 67:4275-4283  DOI:10.1021/jo016413f  PMID:12054963
  • Scheidt, K. A., Tasaka, A., Bannister, T. D., Wendt, M. D., Roush, W. R. Total synthesis of (-)-bafilomycin A(1): application of diastereoselective crotylboration and methyl ketone aldol reactions Angewandte Chemie-International Edition  1999 38:1652-1655  DOI:10.1002/(sici)1521-3773(19990601)38:11<1652::aid-anie1652>3.0.co;2-k
  • Scheidt, K. A., Roush, W. R., McKerrow, J. H., Selzer, P. M., Hansell, E., Rosenthal, P. J. Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors Bioorganic & Medicinal Chemistry  1998 6:2477-2494  DOI:10.1016/s0968-0896(98)80022-9  PMID:9925304
  • Roush, W. R., Gwaltney, S. L., Cheng, J. M., Scheidt, K. A., McKerrow, J. H., Hansell, E. Vinyl sulfonate esters and vinyl sulfonamides: potent, irreversible inhibitors of cysteine proteases Journal of the American Chemical Society  1998 120:10994-10995  DOI:10.1021/ja981792o
  • Scheidt, K. A., Chen, H., Follows, B. C., Chemler, S. R., Coffey, D. S., Roush, W. R. Tris(dimethylamino)sulfonium difluorotrimethylsilicate, a mild reagent for the removal of silicon protecting groups Journal of Organic Chemistry  1998 63:6436-6437  DOI:10.1021/jo981215i