recent publications

• academic article

  • Phad, G. E., Vázquez Bernat, N., Feng, Y., Ingale, J., Martinez Murillo, P. A., O'Dell, S., Li, Y., Mascola, J. R., Sundling, C., Wyatt, R. T., Karlsson Hedestam, G. B. Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization Journal of Immunology  2015 194:5903-5914  DOI:10.4049/jimmunol.1500122  PMID:25964491  PMCID:PMC4458414
  • Martinez, P., Sundling, C., O'Dell, S., Mascola, J. R., Wyatt, R. T., Hedestam, G. B. K. Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation Scientific Reports  2015 5:8925  DOI:10.1038/srep08925  PMID:25762407  PMCID:PMC4356977
  • Navis, M., Tran, K., Bale, S., Phad, G. E., Guenaga, J., Wilson, R., Soldemo, M., McKee, K., Sundling, C., Mascola, J., Li, Y., Wyatt, R. T., et al. HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization PLoS Pathogens  2014 10:e1004337  DOI:10.1371/journal.ppat.1004337  PMID:25166308  PMCID:PMC4148451
  • Sundling, C., Zhang, Z., Phad, G. E., Sheng, Z., Wang, Y., Mascola, J. R., Li, Y., Wyatt, R. T., Shapiro, L., Hedestam, G. B. K. Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization Journal of Immunology  2014 192:3637-3644  DOI:10.4049/jimmunol.1303334  PMID:24623130  PMCID:PMC3993955
  • Tran, K., Poulsen, C., Guenaga, J., de Val, N., Wilson, R., Sundling, C., Li, Y., Stanfield, R. L., Wilson, I. A., Ward, A. B., Hedestam, G. B. K., Wyatt, R. T. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign Proceedings of the National Academy of Sciences of the United States of America  2014 111:E738-E747  DOI:10.1073/pnas.1319512111  PMID:24550318  PMCID:PMC3932900
  • Sundling, C., Li, Y. X., Huynh, N., Poulsen, C., Wilson, R., O'Dell, S., Feng, Y., Mascola, J. R., Wyatt, R. T., Hedestam, G. B. K. High-resolution definition of vaccine-elicited b cell responses against the hiv primary receptor binding site Science Translational Medicine  2012 4:142ra96  DOI:10.1126/scitranslmed.3003752  PMID:22786681
  • Sundling, C., O'Dell, S., Douagi, I., Forsell, M. N., Morner, A., Lore, K., Mascola, J. R., Wyatt, R. T., Hedestam, G. B. K. Immunization with wild-type or cd4-binding-defective hiv-1 env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus Journal of Virology  2010 84:9086-9095  DOI:10.1128/jvi.01015-10  PMID:20610729  PMCID:PMC2937612
  • Douagi, I., Forsell, M. N. E., Sundling, C., O'Dell, S., Feng, Y., Dosenovic, P., Li, Y. X., Seder, R., Lore, K., Mascola, J. R., Wyatt, R. T., Hedestam, G. B. K. Influence of novel cd4 binding-defective hiv-1 envelope glycoprotein immunogens on neutralizing antibody and t-cell responses in nonhuman primates Journal of Virology  2010 84:1683-1695  DOI:10.1128/jvi.01896-09  PMID:19955308  PMCID:PMC2812383
  • Sundling, C., Forsell, M. N. E., O'Dell, S., Feng, Y., Chakrabarti, B., Rao, S. S., Lore, K., Mascola, J. R., Wyatt, R. T., Douagi, I., Hedestam, G. B. K. Soluble hiv-1 env trimers in adjuvant elicit potent and diverse functional b cell responses in primates Journal of Experimental Medicine  2010 207:2003-2017  DOI:10.1084/jem.20100025  PMID:20679401  PMCID:PMC2931166
  • Morner, A., Douagi, I., Forsell, M. N. E., Sundling, C., Dosenovic, P., O'Dell, S., Dey, B., Kwong, P. D., Voss, G., Thorstensson, R., Mascola, J. R., Wyatt, R. T., et al. Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein Journal of Virology  2009 83:540-551  DOI:10.1128/jvi.01102-08  PMID:19004960  PMCID:PMC2612354
  • Sundling, C., Schon, K., Morner, A., Forsell, M. N. E., Wyatt, R. T., Thorstensson, R., Hedestam, G. B. K., Lycke, N. Y. Cta1-dd adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization Journal of General Virology  2008 89:2954-2964  DOI:10.1099/vir.0.2008/005470-0  PMID:19008380