recent publications
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academic article
- Phad, G. E., Vázquez Bernat, N., Feng, Y., Ingale, J., Martinez Murillo, P. A., O'Dell, S., Li, Y., Mascola, J. R., Sundling, C., Wyatt, R. T., Karlsson Hedestam, G. B. Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization Journal of Immunology 2015 194:5903-5914 DOI:10.4049/jimmunol.1500122 PMID:25964491 PMCID:PMC4458414
- Martinez, P., Sundling, C., O'Dell, S., Mascola, J. R., Wyatt, R. T., Hedestam, G. B. K. Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation Scientific Reports 2015 5:8925 DOI:10.1038/srep08925 PMID:25762407 PMCID:PMC4356977
- Navis, M., Tran, K., Bale, S., Phad, G. E., Guenaga, J., Wilson, R., Soldemo, M., McKee, K., Sundling, C., Mascola, J., Li, Y., Wyatt, R. T., et al. HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization PLoS Pathogens 2014 10:e1004337 DOI:10.1371/journal.ppat.1004337 PMID:25166308 PMCID:PMC4148451
- Sundling, C., Zhang, Z., Phad, G. E., Sheng, Z., Wang, Y., Mascola, J. R., Li, Y., Wyatt, R. T., Shapiro, L., Hedestam, G. B. K. Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization Journal of Immunology 2014 192:3637-3644 DOI:10.4049/jimmunol.1303334 PMID:24623130 PMCID:PMC3993955
- Tran, K., Poulsen, C., Guenaga, J., de Val, N., Wilson, R., Sundling, C., Li, Y., Stanfield, R. L., Wilson, I. A., Ward, A. B., Hedestam, G. B. K., Wyatt, R. T. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign Proceedings of the National Academy of Sciences of the United States of America 2014 111:E738-E747 DOI:10.1073/pnas.1319512111 PMID:24550318 PMCID:PMC3932900
- Sundling, C., Li, Y. X., Huynh, N., Poulsen, C., Wilson, R., O'Dell, S., Feng, Y., Mascola, J. R., Wyatt, R. T., Hedestam, G. B. K. High-resolution definition of vaccine-elicited b cell responses against the hiv primary receptor binding site Science Translational Medicine 2012 4:142ra96 DOI:10.1126/scitranslmed.3003752 PMID:22786681
- Sundling, C., O'Dell, S., Douagi, I., Forsell, M. N., Morner, A., Lore, K., Mascola, J. R., Wyatt, R. T., Hedestam, G. B. K. Immunization with wild-type or cd4-binding-defective hiv-1 env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus Journal of Virology 2010 84:9086-9095 DOI:10.1128/jvi.01015-10 PMID:20610729 PMCID:PMC2937612
- Douagi, I., Forsell, M. N. E., Sundling, C., O'Dell, S., Feng, Y., Dosenovic, P., Li, Y. X., Seder, R., Lore, K., Mascola, J. R., Wyatt, R. T., Hedestam, G. B. K. Influence of novel cd4 binding-defective hiv-1 envelope glycoprotein immunogens on neutralizing antibody and t-cell responses in nonhuman primates Journal of Virology 2010 84:1683-1695 DOI:10.1128/jvi.01896-09 PMID:19955308 PMCID:PMC2812383
- Sundling, C., Forsell, M. N. E., O'Dell, S., Feng, Y., Chakrabarti, B., Rao, S. S., Lore, K., Mascola, J. R., Wyatt, R. T., Douagi, I., Hedestam, G. B. K. Soluble hiv-1 env trimers in adjuvant elicit potent and diverse functional b cell responses in primates Journal of Experimental Medicine 2010 207:2003-2017 DOI:10.1084/jem.20100025 PMID:20679401 PMCID:PMC2931166
- Morner, A., Douagi, I., Forsell, M. N. E., Sundling, C., Dosenovic, P., O'Dell, S., Dey, B., Kwong, P. D., Voss, G., Thorstensson, R., Mascola, J. R., Wyatt, R. T., et al. Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein Journal of Virology 2009 83:540-551 DOI:10.1128/jvi.01102-08 PMID:19004960 PMCID:PMC2612354
- Sundling, C., Schon, K., Morner, A., Forsell, M. N. E., Wyatt, R. T., Thorstensson, R., Hedestam, G. B. K., Lycke, N. Y. Cta1-dd adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization Journal of General Virology 2008 89:2954-2964 DOI:10.1099/vir.0.2008/005470-0 PMID:19008380