recent publications

• academic article

  • Boger, D. L., Brunette, S. R., Garbaccio, R. M. Synthesis and evaluation of a series of C3-substituted CBI analogues of CC-1065 and the duocarmycins Journal of Organic Chemistry  2001 66:5163-5173  DOI:10.1021/jo010309g  PMID:11463270
  • Boger, D. L., Fink, B. E., Brunette, S. R., Tse, W. C., Hedrick, M. P. A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity Journal of the American Chemical Society  2001 123:5878-5891  DOI:10.1021/ja010041a  PMID:11414820
  • Boger, D. L., Santillan, A., Searcey, M., Brunette, S. R., Wolkenberg, S. E., Hedrick, M. P., Jin, Q. Synthesis and evaluation of 1,2,8, 8a-Tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: impact of the alkylation subunit substituents and its implications for DNA alkylation catalysis Journal of Organic Chemistry  2000 65:4101-4111  DOI:10.1021/jo000297j  PMID:10866627