Chemical synthesis and biological properties of pyridine epothilones

Academic Article

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• Research
• Identity
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Overview

authors

• Nicolaou, K.C.
• Scarpelli, R.
• Bollbuck, B.
• Werschkun, B.
• Pereira, M. M. A.
• Wartmann, M.
• Altmann, K. H.
• Zaharevitz, D.
• Gussio, R.
• Giannakakou, P.

publication date

• August 2000

journal

• Chemistry & Biology  Journal

subject areas

• Antineoplastic Agents
• Cell Division
• Drug Design
• Drug Evaluation, Preclinical
• Drug Resistance, Neoplasm
• Epothilones
• Epoxy Compounds
• Humans
• Inhibitory Concentration 50
• Macrolides
• Models, Molecular
• Molecular Structure
• Pyridines
• Structure-Activity Relationship
• Thiazoles
• Tubulin
• Tumor Cells, Cultured

Research

keywords

• antitumor activity
• chemical synthesis
• epothilones
• molecular modeling
• pyridine epothilones

Identity

International Standard Serial Number (ISSN)

• 1074-5521

Digital Object Identifier (DOI)

• 10.1016/s1074-5521(00)00006-5

PubMed ID

• 11048950

Additional Document Info

start page

• 593

end page

• 599

volume

• 7

issue

• 8