Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acids

Academic Article
uri icon

related to degree

  • Wang, Donghui, Ph.D., Scripps Research , transferred from Brandeis Univeristy 2007 - 2010

publication date

  • January 2010

abstract

  • Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acid substrates has been achieved through the use of monoprotected chiral amino acid ligands. The absolute configuration of the resulting olefinated products is consistent with that of a proposed C-H insertion intermediate.